Results 151 to 160 of about 2,994 (188)
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Thrombotic microangiopathy in pregnancy
Thrombosis Research, 2009Following the initial reports by Moschowitz in 1925 [1] and by Baehr et al. in 1936 [2], Singer [3] and Gasser [4] suggested the terms of “thrombotic thrombocytopenic purpura, TTP” and of “hemolytic uremic syndrome, HUS” to describe related disorders consisting of Coombs’ negative hemolytic anemia, thrombocytopenia, and renal failure.
Armando, D'Angelo +2 more
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2019
Abstract The thrombotic microangioapathy (TMA) syndromes are characterized by concomitant occurrence of severe thrombocytopenia, microangiopathic hemolytic anemia, and ischemic end organ dysfunction often of the kidneys. While several of their features overlap in terms of clinical presentation, the pathophysiology and underlying causes ...
Harpreet Singh +2 more
+4 more sources
Abstract The thrombotic microangioapathy (TMA) syndromes are characterized by concomitant occurrence of severe thrombocytopenia, microangiopathic hemolytic anemia, and ischemic end organ dysfunction often of the kidneys. While several of their features overlap in terms of clinical presentation, the pathophysiology and underlying causes ...
Harpreet Singh +2 more
+4 more sources
Syndromes of Thrombotic Microangiopathy
Medical Clinics of North America, 2017Thrombotic thrombocytopenia purpura (TTP) and the hemolytic uremic syndrome (HUS) are rare thrombotic microangiopathies that can be rapidly fatal. Although the acquired versions of TTP and HUS are generally highest on this broad differential, multiple rarer entities can produce a clinical picture similar to TTP/HUS, including microangiopathic hemolysis,
Joseph J, Shatzel, Jason A, Taylor
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Thrombotic Microangiopathy in Cancer
Seminars in Thrombosis and Hemostasis, 2018AbstractThrombotic microangiopathy (TMA) is a rare but often devastating complication of cancer and cancer treatment. The syndrome is defined by thrombocytopenia (i.e., a platelet count of < 150,000/mcL or > 30% decrease from baseline), microangiopathic hemolytic anemia, and some evidence of organ damage.
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Thrombotic Microangiopathy in the Cancer Patient
Acta Haematologica, 2001Thrombotic microangiopathy, manifesting as thrombotic thrombocytopenic purpura (TTP) or hemolytic uremic syndrome, is a common complication in cancer patients. It shares the pathogenic microvascular occlusive lesion and many clinical manifestations as the classical TTP, but the spectrum of complications varies widely.
H C, Kwaan, L I, Gordon
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Gemcitabine‐induced thrombotic microangiopathy
Internal Medicine Journal, 2013AbstractThrombotic microangiopathy (TMA) is a microvascular occlusive disorder characterised by platelet aggregation, thrombocytopenia and end‐organ damage. It is commonly idiopathic, although several drug classes, including cytotoxic chemotherapy, have been implicated.
Richmond, J., Gilbar, P., Abro, E.
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Thrombotic Microangiopathies and the Kidney
Advances in Kidney Disease and HealthThrombotic microangiopathy (TMA) is a pathological lesion that occurs due to endothelial injury. It can be seen in a heterogenous group of disorders, typically characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ ischemia. TMA can also be renal limited with no systemic manifestations.
Anuja Java +2 more
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Der Internist, 2013
Thrombotic microangiopathy should be suspected every time the combination of microangiopathic hemolytic anemia without a coexisting cause, thrombocytopenia as well as renal and/or neurologic abnormalities occurs. The general term thrombotic microangiopathy includes different subtypes of the disease leading to abnormalities in multiple organ systems by ...
Ganser, A., Kielstein, J. T., Beutel, G.
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Thrombotic microangiopathy should be suspected every time the combination of microangiopathic hemolytic anemia without a coexisting cause, thrombocytopenia as well as renal and/or neurologic abnormalities occurs. The general term thrombotic microangiopathy includes different subtypes of the disease leading to abnormalities in multiple organ systems by ...
Ganser, A., Kielstein, J. T., Beutel, G.
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Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2023
In the emergency room, patients with anemia and thrombocytopenia are common. Although these findings can often be explained by the medical situation, thrombotic microangiopathy is an important differential diagnosis. In this case, occlusion of the smallest vessels consequently leads to functional impairment of the affected organs.
Tilman, Schmidt, Tobias B, Huber
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In the emergency room, patients with anemia and thrombocytopenia are common. Although these findings can often be explained by the medical situation, thrombotic microangiopathy is an important differential diagnosis. In this case, occlusion of the smallest vessels consequently leads to functional impairment of the affected organs.
Tilman, Schmidt, Tobias B, Huber
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Der nephrologe
Thrombotic microangiopathy (TMA) is characterized by an endothelium injury-associated formation of platelet clots in arterial and venous microvessels. Concomitant ischemia causes severe organ dysfunction and can be acutely life threatening. The underlying etiology of TMA shows a very heterogeneous disease spectrum.
Anja, Gäckler, Oliver, Witzke
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Thrombotic microangiopathy (TMA) is characterized by an endothelium injury-associated formation of platelet clots in arterial and venous microvessels. Concomitant ischemia causes severe organ dysfunction and can be acutely life threatening. The underlying etiology of TMA shows a very heterogeneous disease spectrum.
Anja, Gäckler, Oliver, Witzke
openaire +3 more sources