Results 81 to 90 of about 5,025 (225)

Impact of High Serum Lysozyme Activity on Renal Function and Survival Outcomes in Transplant‐Eligible and Ineligible Acute Myeloid Leukemia

Cancer Medicine, Volume 15, Issue 3, March 2026.
At AML initial diagnosis, the lysozyme and creatinine levels were positively correlated. However, the effect of lysozyme levels on AML prognosis is limited, because renal function recovers in many patients with high‐lysozyme levels after chemotherapy. ABSTRACT Lysozyme‐induced nephropathy is a complication of chronic myelomonocytic leukemia and acute ...
Takafumi Tsushima, Kosuke Matsuo, Akihiro Shoji, Chiharu Kimeda, Rena Matsumoto, Sonoko Shimoji, Yoshikazu Utsu, Shin‐Ichi Masuda, Nobuyuki Aotsuka   +8 more
wiley   +1 more source

Hereditary Thrombotic Thrombocytopenic Purpura Associated With Recurrent Strokes and Prominent Nervous System Involvement in a Young Chinese Female

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Hereditary thrombotic thrombocytopenic purpura (TTP) is a rare autosomal recessive inherited disease caused by an ADAMTS1 gene mutation, resulting in absence or severe deficiency of plasma ADAMTS13 activity. The common causes include infection, inflammation, or pregnancy.
Wanying Liu, Jiaying Wu, Xi Ming, Qi Zhang, Delian Zhou, Rubing Zheng, Mi Zhou, Zhen Shang, Liting Chen, Xiaojian Zhu, Yi Xiao   +10 more
wiley   +1 more source

Acute Kidney Injury in Pregnancy: The Changing Landscape for the 21st Century

Kidney International Reports, 2018
Pregnancy-related acute kidney injury (Pr-AKI) remains a large public health problem, with decreasing incidences in developing countries but seemingly increasing incidences in the United States and Canada.
Swati Rao, Belinda Jim
doaj   +1 more source

Renal‐Limited Thrombotic Microangiopathy due to Anti‐VEGF/TKI Immunotherapy for Metastatic Renal Cell Carcinoma Presenting as Nephrotic Syndrome: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Vascular endothelial growth factor (VEGF) inhibition may result in proteinuria, worsening hypertension, chronic kidney injury, or glomerular disease. Recently, systemic VEGF inhibition has been reported to cause nephrotic disorders and thrombotic microangiopathy (TMA).
Sundus Sardar, Ahmad Matarneh, Omar K. Salameh, Abdel‐Rauof M. Akkari, Monika Joshi, Erik Washburn, Nasrollah Ghahramani, Naman Trivedi   +7 more
wiley   +1 more source

A patient with SLE-associated thrombotic microangiopathy and non-neutralizing antibodies against ADAMTS13 [PDF]

, 2017
In this case report, we describe for the first time a patient with thrombotic thrombocytopaenic purpura (TTP) accompanying highly active systemic lupus erythematosus (SLE) that was associated with non-neutralizing antibodies against the plasma ...
Ferrari, Silvia, Knecht, Margrith E., Mayr, Michael, Scheiflinger, Friedrich, Trendelenburg, Marten   +4 more
core  

Degradation of two novel congenital TTP ADAMTS13 mutants by the cell proteasome prevents ADAMTS13 secretion [PDF]

, 2016
INTRODUCTION: Over 150 mutations have been identified in the ADAMTS13 gene in patients with congenital thrombotic thrombocytopenic purpura (TTP). The majority of these (86%), lead to reduced (
Garagiola, I, Machin, S, Mackie, I, Peyvandi, F, Underwood, M   +4 more
core   +1 more source

From Hemolysis to Lupus: A Case of Evans Syndrome Revealing Systemic Autoimmunity

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Evans syndrome (ES), the coexistence of autoimmune hemolytic anemia and immune thrombocytopenia, can unmask systemic autoimmune disease. We report a 30‐year‐old woman who presented with fatigue, jaundice, pallor, and mucocutaneous bleeding.
Biruk T. Mengistie, Chernet T. Mengistie, Mikiyas G. Teferi, Daniel C. Teka, Alefe Kedame Godifey, Abel G. Wubie, Bruke Z. Abenet   +6 more
wiley   +1 more source

Thrombotic Thrombocytopenic Purpura in a Patient With Triple‐Negative Breast Cancer Treated With PD‐L1 Inhibition and Taxane Chemotherapy

Clinical Case Reports, Volume 14, Issue 3, March 2026.
PET imaging of a 56 year old woman with HIV and advanced triple negative breast cancer with regional lymph node and bone metastases. ABSTRACT Thrombocytopenic purpura (TTP) is a hematologic emergency that may occur with PD‐L1 immunotherapy. New or worsening anemia and thrombocytopenia in patients started on PD‐L1 inhibitors should raise suspicion for ...
Jason Ke, Albert C. Chong, Robert Hsu, Anastasia Martynova, Noah Wald‐Dickler, Anishka D'Souza, Caroline Piatek, Gino K. In   +7 more
wiley   +1 more source

ADAMTS-13 in the Diagnosis and Management of Thrombotic Microangiopathies

Rambam Maimonides Medical Journal, 2014
Thrombotic microangiopathies (TMAs) comprise a group of distinct disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microvascular thrombosis.
Galit Sarig
doaj   +1 more source

Idiopathic combined, autoantibody-mediated ADAMTS-13/factor H deficiency in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in a 17-year-old woman: a case report [PDF]

, 2011
Introduction Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome is a life-threatening condition with various etiopathogeneses. Without therapy approximately 90% of all patients die from the disease. Case presentation We report the case of a 17-
Daniel Patschan, Peter Korsten, Arne Behlau, Radovan Vasko, Malte Heeg, Nadera Sweiss, Gerhard A Müller, Michael Koziolek   +7 more
core   +1 more source