Results 61 to 70 of about 27,505 (253)

A rare case of hereditary thrombotic thrombocytopenic purpura in a toddler

Liječnički vjesnik, 2023
Hereditary thrombotic thrombocytopenic purpura (hTTP) is a thrombotic microangiopathy caused by pathogenic variants in the ADAMTS13 gene resulting in highly reduced activity of von Willebrand factor-cleaving metalloprotease.
Ozana Jakšić, Jana Jelčić, Maša Davidović   +2 more
doaj   +1 more source

Elevated plasma neutrophil elastase concentration is associated with disease activity in patients with thrombotic thrombocytopenic purpura. [PDF]

, 2015
INTRODUCTION: Genetic and autoimmune risk factors contribute to the development of thrombotic thrombocytopenic purpura (TTP) but triggers are needed to bring about acute disease.
Brill, Brinkmann, Brinkmann, Bálint Mikes, Chapman, Chaturvedi, Chen, Clark, Clark, Derzsy, Dorottya Csuka, Falter, Fitzpatrick, Fuchs, Fujimura, Gombos, Gyula Domján, György Sinkovits, Hung, Ishikawa, Jagels, Judit Demeter, Karpman, Katalin Rázsó, Kessenbrock, Kremer Hovinga, Leffler, Marienn Réti, Massberg, Moatti-Cohen, Noris, Papayannopoulos, Peng, Peyvandi, Péter Farkas, Raife, Reti, Tsai, Urban, van Montfoort, Walters, Westwood1, Xu, Zoltán Prohászka, Ágota Schlammadinger   +44 more
core   +1 more source

Anti‐ADAMTS13 Antibodies Trajectory is Associated With ADAMTS13 Recovery in Immune‐Mediated TTP

American Journal of Hematology, Volume 100, Issue 10, Page 1736-1746, October 2025.
Anti‐ADAMTS13 IgG antibodies titer trajectory from baseline to day 7–14 post‐TPE as a reliable approach to identify iTTP patients at risk of late response to the triplet therapy regimen. ABSTRACT Current triplet regimens associating therapeutic plasma exchange (TPE), immunosuppression with corticosteroids and rituximab, and caplacizumab have ...
Marie Robert, Arthur Mageau, Ygal Benhamou, François Provôt, Jehane Fadlallah, Lionel Galicier, Elie Azoulay, Hafid Ait‐Oufella, Tomas Urbina, Pascale Poullin, Alain Wynckel, Coralie Poulain, Nihal Martis, Pierre Perez, Virginie Rieu, Yahsou Delmas, Jean‐Michel Halimi, Christelle Barbet, Amélie Seguin, Valérie Chatelet, Jean‐François Augusto, Mathieu Legendre, Olivier Moranne, Carole Philipponnet, Bérengère Cador, Raïda Bouzid, Bérangère S. Joly, Agnès Veyradier, Paul Coppo, on behalf of the French Reference Center for Thrombotic Microangiopathies, Augusto Jean‐François, Azoulay Elie, Barbay Virginie, Benhamou Ygal, Charasse Christophe, Charvet‐Rumpler Anne, Chauveau Dominique, Ribes Davis, Choukroun Gabriel, Coindre Jean‐Philippe, Coppo Paul, Delmas Yahsou, Kwon Theresa, Salanoubat Célia, Dossier Antoine, Fain Olivier, Ville Simon, Frémeaux‐Bacchi Véronique, Galicier Lionel, Grangé Steven, Guidet Bertrand, Halimi Jean‐Michel, Hamidou Mohamed, Neel Antoine, Fornecker Luc‐Matthieu, Hié Miguel, Jacobs Frédéric, Joly Bérangère, Kanouni Tarik, Kaplanski Gilles, Rieu Claire, Le Guern Véronique, Moulin Bruno, Rebibou Jean‐Michel, Ojeda Uribe Mario, Parquet Nathalie, Pène Frédéric, Perez Pierre, Poullin Pascale, Marie Manon, Presne Claire, Provôt François, Mesnard Laurent, Saheb Samir, Seguin Amélie, Servais Aude, Stépanian Alain, Veyradier Agnès, Vigneau Cécile, Wynckel Alain, Zunic Patricia   +80 more
wiley   +1 more source

Sunitinib Induced Thrombotic Thrombocytopenic Purpura in addition to Severe Hypothyroidism: A Case Report and Review of the Literature

Case Reports in Medicine, 2014
Introduction. Sunitinib malate is an oral multitargeting tyrosine kinase inhibitor approved for the first line treatment of metastatic renal cell carcinoma.
Imane El Dika, Deborah Mukherji, Sally Temraz, Rita Assi, Ali Shamseddine   +4 more
doaj   +1 more source

Thrombotic Thrombocytopenic Purpura and Gemcitabine [PDF]

Case Reports in Oncology, 2011
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening complication of gemcitabine treatment. Since the approval of this nucleoside analog for the treatment of pancreatic cancer by the FDA in 1996, reported incidence varies from 0.015 to 1.4%.
openaire   +4 more sources

Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK [PDF]

, 2018
Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased
Cardwell, J M, Holm, L P, Jepson, R E, O'Neill, D G, Stevens, K B, Walker, D J   +5 more
core   +2 more sources

Trastuzumab Deruxtecan for Human Epidermal Growth Factor Receptor 2‐Low Breast Cancer With Cancer‐Related Microangiopathic Hemolytic Anemia: A Case Report

Cancer Innovation, Volume 4, Issue 5, October 2025.
The diagnosis and treatment of acquired hemolytic anemia can be challenging. In breast cancer patients, it may be directly associated with the underlying malignancy (as an initial presentation or during disease progression). The diagnosis of cancer‐related microangiopathic hemolytic anemia (CR‐MAHA) is often delayed, and patients have a high mortality ...
Mengyuan Li, Mao Ding, Yukun Hou, Xuening Duan, Yuanjia Cheng, Ling Xu   +5 more
wiley   +1 more source

Presumptive thrombotic thrombocytopenic purpura following a hump-nosed viper (Hypnale hypnale) bite: a case report

Journal of Venomous Animals and Toxins including Tropical Diseases, 2014
Hump-nosed viper bites are frequent in southern India and Sri Lanka. However, the published literature on this snakebite is limited and its venom composition is not well characterized.
Milinda Withana, Chaturaka Rodrigo, Ariaranee Gnanathasan, Lallindra Gooneratne   +3 more
doaj   +1 more source

Diagnosis of thrombotic thrombocytopenic purpura

Terapevticheskii arkhiv, 2020
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disease, disease, characterised by microangiopathic hemolytic anaemia, consumption thrombocytopenia, and organ dysfunction. The pathogenesis of TTP is attributed to the deficiency in the activity of the metalloproteinase ADAMTS13, specific von Willebrand factor cleaving protease. TTP
G. M. Galstyan, E. E. Klebanova
openaire   +4 more sources

BMQ [PDF]

, 1963
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Antuna, Juan, Bagnoli, Thomas, Barber, Doris E., Cocchiarella, John P., Duke, Martin, Estes, J. Worth, Friedlander, Walter J., Goldsmith, Harry S., Gooding, Gretchen W., Goofman, Max L., Haseotes, Hytho V., Hass, Gerald, Hastings, A. Baird, Jackson, David R., Johnson, David S., Kechejian, Sarkis J., Kramer, Philip, Litman, George I., Madoff, Irving M., McLellan, Patricia A., O'Hara, Vincent S., Peabody, C. Newton, Pryles, Charles V., Small, Donald M., Tedeschi, Luke G., Walker, Sydney, III   +25 more
core