Results 101 to 110 of about 47,275 (224)
Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys
, 1986 Twenty-four hours of complete unilateral ureteral obstruction (UUO) produces intense renal vasconstriction in the rat even after release of obstruction.
S. R. Smith +4 more
core +1 more source
Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management
MedComm, Volume 7, Issue 10, October 2026.Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi +9 more
wiley +1 more source
PAR-4 Agonist AYPGKF Stimulates Thromboxane Production by Human Platelets
, 2002 Previous reports have indicated that thrombin-induced thromboxane production by human platelets occurs through two types of interaction between thrombin and the platelet surface.
Vallere K. Hanks, Ruth Ann Henriksen
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi +13 more
wiley +1 more source
Characterization of thromboxane and prostacyclin effects on pulmonary vascular resistance
, 1992 Although thromboxane and prostacyclin (PGI2) have long been described as major controllers of pulmonary vascular resistance, little has been reported on the characteristics of the interactions between the two arachidonic acid products. The current study
A. E. Taylor +3 more
core +1 more source
Effect of Glucose or Fat Challenge on Aspirin Resistance in Diabetes
International Journal of Endocrinology, 2010 Aspirin has lower antiplatelet activity in diabetic patients. Our aim is to study the roles of acute hyperglycemia and hyperlipidemia on aspirin function in diabetic subjects with and without cardiovascular disease.
Hussein N. Yassine +5 more
doaj +1 more source
British Journal of Pharmacology, Volume 183, Issue 20, Page 5999-6006, October 2026.Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley +1 more source
Journal of Fish Diseases, Volume 49, Issue 10, October 2026.ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English +4 more
wiley +1 more source
Thromboxane-induced pulmonary vasoconstriction: involvement of calcium
, 1985 Infusion of tert-butyl hydroperoxide (t-bu-OOH) or arachidonic acid into rabbit pulmonary arteries stimulated thromboxane B2 (TxB2) production and caused pulmonary vasoconstriction.
N. F. Adkinson +4 more
core +1 more source
Preservation of ischemic myocardium by pinane thromboxane A2
, 1980 Pinane thromboxane A2 (PTA2), a thromboxane A2 analog has been shown to antagonize the vasoconstriction and platelet aggregation induced by thromboxane A2, in addition to specifically inhibiting thromboxane synthetase.
M. Bickerton +6 more
core +1 more source