Results 91 to 100 of about 286,478 (209)

Modulation of Human Monocyte Leukotactic Responsiveness by Thromboxane A2 and 12-Hydroxyheptadecatrienoic Acid (12-HHT)

open access: yes, 1988
The leukotactic responsiveness of human peripheral blood monocytes is regulated by the cell-directed inhibitor of monocyte leukotaxis, CDI-MLx. The actions of CDI-MLx on normal monocytes in vitro were abrogated by co-incubation with inhibitors of ...
Timothy A Tolson, Peter B Campbell
core   +1 more source

Evidence of a thromboxane A2-Ca2+ complex: a conformational approach. [PDF]

open access: yes, 1984
Thromboxane A2 has been proposed as an ionophore capable to transport calcium from the platelet dense tubular system to the cytoplasm to activate the contractile proteins.
Ruysschaert, Jean-Marie   +2 more
core  

Inhibition of thromboxane A2 production does not improve post-ischemic brain hypoperfusion in the dog.

open access: yes, 1986
In a canine model of global brain ischemia, six dogs received a selective thromboxane A2 synthetase inhibitor, UK 38,485 (dazmagrel) before the ischemic event; six received a saline placebo.
W C Beamer   +5 more
core   +1 more source

Mechanism of coronary vasoconstriction induced by carbocyclic thromboxane A2

open access: yes, 1981
The mechanism of carbocyclic thromboxane A2 (CTA2) vasoconstriction was studied in thoracic aortic strips and isolated perfused cat coronary arteries. CTA2, a stable thromboxane analog, produced coronary constriction at 50 pg/ml or greater.
E. F. Smith, K. C. Nicolaou, A. M. Lefer
core   +1 more source

Sex differences in middle cerebral artery reactivity and hemodynamics independent from changes in systemic arterial stiffness in Sprague–Dawley rats

open access: yesPhysiological Reports
The mechanisms of sex differences in cerebrovascular function are not well understood. In this study, we determined whether sex differences in middle cerebral artery (MCA) reactivity are accompanied with changes in cerebral or systemic arterial ...
Jonathan W. Ray   +4 more
doaj   +1 more source

Thromboxane A2 induces cell signaling but requires platelet-derived growth factor to act as a mitogen

open access: yes, 1997
Grosser T, Zucker T-P, Weber A-A, et al. Thromboxane A2 induces cell signaling but requires platelet-derived growth factor to act as a mitogen. European Journal of Pharmacology.
Grosser, Tilo ; https://orcid.org/   +13 more
core   +1 more source

Selective modulation of the platelet thromboxane A2/prostaglandin H2 receptor by omega-3 fatty acids.

open access: yes, 1992
Selective modulation of the platelet thromboxane A2/prostaglandin H2 receptor by omega-3 fatty ...
Carole Anne. Parent (7998806)
core   +2 more sources

Development of original 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as thromboxane A2 receptor antagonists

open access: yes, 2012
A series of novel 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas were synthesized. The newly synthesized compounds were tested in vitro and ex vivo as thromboxane A2 receptor antagonists.
Bambi Nyanguile, Sylvie-Mireille   +3 more
core   +1 more source

Effects of Fatty Acid Metabolites on Adipocytes Britening: Role of Thromboxane A2. [PDF]

open access: yesCells, 2023
Colson C   +14 more
europepmc   +1 more source

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