Results 111 to 120 of about 9,969 (239)

Urotensin II Receptor Deletion Mitigates Kidney Injury and Renal Lipid Remodeling in Mice Fed a Long‐Term High‐Fat Diet

open access: yesFASEB BioAdvances, Volume 8, Issue 9, September 2026.
Urotensin II receptor deletion mitigates high‐fat diet‐induced kidney injury and renal lipid remodeling. Male wild‐type (WT) and urotensin II receptor–knockout (UT KO) mice were fed a high‐fat diet (HFD; 60% kcal from fat) for 33 weeks. In cultured mouse podocytes, urotensin II (UII)–UT signaling enhanced transient receptor potential canonical 6 (TRPC6)
Praghalathan Kanthakumar   +1 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, Volume 81, Issue 9, Page 3039-3070, September 2026.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter   +20 more
wiley   +1 more source

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 17, Page 5389-5406, September 2026.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi   +10 more
wiley   +1 more source

Thromboxan [PDF]

open access: yes, 2017
A. M. Gressner, O. A. Gressner
openaire   +1 more source

Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1445-1453, September 2026.
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers   +2 more
wiley   +1 more source

Urinary thromboxane and isoprostane levels are elevated in symptom-high T2-biomarker-low severe asthma

open access: yesERJ Open Research
Background ∼5–10% of patients with asthma have severe disease. A proportion remain symptomatic despite suppression of T2-related inflammation but what drives persistent symptoms remains unclear.
Matthew Chad Eastwood   +23 more
doaj   +1 more source

On the History of Hepatic Vein Catheterization

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five years passed before pressure measurements were performed and routine HVCs were
Jens Henrik Henriksen   +2 more
wiley   +1 more source

Xenotransplantation of the Porcine Lung—From Immunological Barriers to Emerging Experimental Strategies

open access: yesXenotransplantation, Volume 33, Issue 5, September/October 2026.
ABSTRACT Lung transplantation is the only long‐lasting life‐saving treatment for patients with end‐stage pulmonary disease, but the ever‐growing shortage of suitable donor organs leads to high mortality rates of the afflicted patients. Xenotransplantation, the transplantation of organs across species, has emerged as a promising alternative. This review
Nathalie Roters   +6 more
wiley   +1 more source

Role of eicosanoids in airway smooth muscle tone

open access: yes, 1988
LR: 20061115; PUBM: Print; JID: 7605701; 0 (Prostaglandins); 0 (Receptors, Prostaglandin); 0 (Thromboxanes); RF: 36; ppublish Monograph title: Airways: pharmacology, physiology, management.Source type: Electronic ...

core  

Long-chain n-3 fatty acids and inflammation: potential application in surgical and trauma patients

open access: yesBrazilian Journal of Medical and Biological Research, 2003
Lipids used in nutritional support of surgical or critically ill patients have been based on soybean oil, which is rich in the n-6 fatty acid linoleic acid (18:2n-6). Linoleic acid is the precursor of arachidonic acid (20:4n-6). In turn, arachidonic acid
Calder P.C.
doaj  

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