Results 21 to 30 of about 591,278 (261)
Cost Estimation Tool for Metallic Parts Made by Casting: A Case Study
Metals, 2023 This work presents a mathematical tool to estimate the cost of fabricating pumps by traditional casting. The drivers that most affect the cost of the process are identified in each step of the procedure, i.e., material, labour, energy, tools and general ...
Itziar Iraola-Arregui +2 more
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High‐Throughput SNP Genotyping [PDF]
ChemInform, 2002 AbstractWhole genome approaches using single nucleotide polymorphism (SNP) markers have the potential to transform complex disease genetics and expedite pharmacogenetics research. This has led to a requirement for high‐throughput SNP genotyping platforms. Development of a successful high‐throughput genotyping platform depends on coupling reliable assay
Jenkins, Suzanne, Gibson, Neil
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SLAS DiscoveryAnimal testing for drug discovery is expensive and the decision to test a compound in an in vivo model should be carefully considered. In addition, the FDA Modernization Act has resulted in the allowance of alternatives to animal models for testing the ...
N. Miranda Nebane +7 more
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High throughput drug profiling [PDF]
Journal of Analytical Methods in Chemistry, 2000 High throughput screening has significantly contributed to advances in drug discovery. The great increase in the number of samples screened has been accompanied by increases in costs and in the data required for the investigated compounds. High throughput profiling addresses the issues of compound selectivity and specificity.
Entzeroth, Michael +3 more
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Decentralized Throughput Scheduling [PDF]
, 2013 Motivated by the organization of distributed service systems, we study models for throughput scheduling in a decentralized setting. In throughput scheduling, a set of jobs $j$ with values $w_j$, processing times $p_{ij}$ on machine $i$, release dates $r_j$ and deadlines $d_j$ , is to be processed non-preemptively on a set of unrelated machines.
de Jong, Jasper +2 more
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BMC Genomics, 2023 Background Chlamydia (C.) psittaci, the causative agent of avian chlamydiosis and human psittacosis, is a genetically heterogeneous species. Its broad host range includes parrots and many other birds, but occasionally also humans (via zoonotic ...
Konrad Sachse +7 more
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High-throughput detection of metal contamination in HTS outputs
SLAS Discovery, 2022 Large compound libraries utilised for HTS often include metal contaminated compounds which can interfere with assay signal or target biology, and therefore appear as hits.
Corinne Molyneux +5 more
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High-throughput tetrad analysis [PDF]
Nature Methods, 2013 Tetrad analysis has been a gold-standard genetic technique for several decades. Unfortunately, the need to manually isolate, disrupt and space tetrads has relegated its application to small-scale studies and limited its integration with high-throughput DNA sequencing technologies.
Ludlow, Catherine L. +9 more
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Protein synthesis rate is the predominant regulator of protein expression during differentiation
Molecular Systems Biology, 2013 External perturbations, by forcing cells to adapt to a new environment, often elicit large‐scale changes in gene expression resulting in an altered proteome that improves the cell's fitness in the new conditions.
Anders R Kristensen +2 more
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Critical Review on Zeolite Clinoptilolite Safety and Medical Applications in vivo
Frontiers in Pharmacology, 2018 Unique and outstanding physical and chemical properties of zeolite materials make them extremely useful in a variety of applications including agronomy, ecology, manufacturing, and industrial processes.
Sandra Kraljević Pavelić +6 more
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