Results 21 to 30 of about 1,097,810 (322)
Nature Communications, 2021 Inhibitor of Differentiation 1 (ID1) is an oncogene for colorectal cancer. Here, the authors show a complex interplay between nuclear receptor Nur77 and Transforming Growth Factor-β (TGFβ) to regulate ID1 expression at both transcriptional and post ...
Boning Niu +9 more
doaj +1 more source
Cutadapt removes adapter sequences from high-throughput sequencing reads
, 2011 When small RNA is sequenced on current sequencing machines, the resulting reads are usually longer than the RNA and therefore contain parts of the 3' adapter.
Marcel Martin
semanticscholar +1 more source
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
Nature Neuroscience, 2009 The Cre/lox system is widely used in mice to achieve cell-type-specific gene expression. However, a strong and universally responding system to express genes under Cre control is still lacking.
L. Madisen +11 more
semanticscholar +1 more source
Cost Estimation Tool for Metallic Parts Made by Casting: A Case Study
Metals, 2023 This work presents a mathematical tool to estimate the cost of fabricating pumps by traditional casting. The drivers that most affect the cost of the process are identified in each step of the procedure, i.e., material, labour, energy, tools and general ...
Itziar Iraola-Arregui +2 more
doaj +1 more source
Journal of biomolecular screening, 1999 The ability to identify active compounds ("hits") from large chemical libraries accurately and rapidly has been the ultimate goal in developing high-throughput screening (HTS) assays.
Ji-Hu Zhang, T. Chung, K. Oldenburg
semanticscholar +1 more source
A perspective on the discovery of enzyme activators
SLAS Discovery, 2022 Enzyme activation remains a largely under-represented and poorly exploited area of drug discovery despite some key literature examples of the successful application of enzyme activators by various mechanisms and their importance in a wide range of ...
Antonia Turberville +4 more
doaj
Ribosomal Database Project: data and tools for high throughput rRNA analysis
Nucleic Acids Res., 2013 Ribosomal Database Project (RDP; http://rdp.cme.msu.edu/) provides the research community with aligned and annotated rRNA gene sequence data, along with tools to allow researchers to analyze their own rRNA gene sequences in the RDP framework.
J. Cole +9 more
semanticscholar +1 more source
High-throughput proteomics: a methodological mini-review
Laboratory Investigation, 2022 Proteomics plays a vital role in biomedical research in the post-genomic era. With the technological revolution and emerging computational and statistic models, proteomic methodology has evolved rapidly in the past decade and shed light on solving ...
Miao Cui, Chao Cheng, Lanjing Zhang
semanticscholar +1 more source
Throughput-Outage Scaling Behaviors for Wireless Single-Hop D2D Caching Networks with Physical Model -- Analysis and Derivations [PDF]
arXiv, 2021 Throughput-Outage scaling laws for single-hop cache-aided device-to-device (D2D) communications have been extensively investigated under the assumption of the protocol model. However, the corresponding performance under physical models has not been explored; in particular it remains unclear whether link-level power control and scheduling can improve ...
arxiv
Bioinform., 2012 Heterogeneity and latent variables are now widely recognized as major sources of bias and variability in high-throughput experiments. The most well-known source of latent variation in genomic experiments are batch effects-when samples are processed on ...
J. Leek +4 more
semanticscholar +1 more source