Results 51 to 60 of about 633,830 (310)
Critique of Hirsch's citation index: a combinatorial Fermi problem [PDF]
, 2014 The h-index was introduced by the physicist J.E. Hirsch in 2005 as measure of a researcher's productivity. We consider the "combinatorial Fermi problem" of estimating h given the citation count.
Yong, Alexander
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Osseous bilateral pseudotumour of the thumb in severe haemophilia A – A case report
The Journal of Haemophilia Practice, 2022 Pseudotumour is a rare complication of haemophilia, categorised as osseous or non-osseous (soft tissue) lesions based on anatomic location. The bones most frequently involved are the larger ones; pseudotumours of small bones are rare.
Mandal Prakas K +2 more
doaj +1 more source
Telephone multiline signaling using common signal pair [PDF]
, 1979 An operator can rapidly and automatically produce coded electrical signals by manipulating mechanical thumb wheel switches so as to instruct a service center to connect any number of telephone lines to the console thus enabling the operator to listen and/
Belt, J. L. +3 more
core +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
The Surgery Journal, 2019 Background Numerous surgeries have been described for osteoarthritis of the trapeziometacarpal (TMC) joint. We describe the senior author's experience with his technique of concurrent arthroplasty of the TMC joint, and carpal tunnel release (CTR) via a ...
Chung Ming Chan +2 more
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message We describe an immunocompromised 73‐year‐old male with a history of neurofibromatosis type 1 (NF1) who presented with a lesion on the thumb concerning for malignancy that was found to be histoplasmosis.
Joshua Marc Levine +2 more
doaj +1 more source
Rule Of Thumb: Deep derotation for improved fingertip detection [PDF]
, 2015 We investigate a novel global orientation regression approach for articulated objects using a deep convolutional neural network. This is integrated with an in-plane image derotation scheme, DeROT, to tackle the problem of per-frame fingertip detection in
Kimmel, Ron +2 more
core +1 more source