Results 91 to 100 of about 695,872 (210)
Nonlinear Aging of the Human TCR Repertoire Is Influenced by Sex, CMV, and Cancer
Aging is associated with a nonlinear decline in peripheral blood TCR repertoire diversity, with an accelerated decline after ~50 years, while sex, CMV infection, and cancer further shape TCR diversity. The age‐associated decrease in diversity was accompanied by shifts in clonal and T cell subtype composition.
Naja Lange +9 more
wiley +1 more source
Thymomas are thymic epithelial tumors. The term thymoma has been customarily restricted to those neoplasms arising from or exhibiting differentiation toward thymic epithelial cells.
張金池;張逸良;李元麒 +1 more
core +1 more source
Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley +1 more source
: Background: Our knowledge of thymic malignancies has largely been derived from small, single-institution series. Recognition of the need for broad collaboration led to the creation of the International Thymic Malignancy Interest Group (ITMIG) and the ...
Ahmad, Usman +4 more
core
When a thymic carcinoma " becomes" a GIST
Thymic carcinoma (TC) is a rare intrathoracic malignancy that it can be invasive and refractory to conventional treatment. Comprehensive genomic analysis evidenced a molecularly distinct subset of thymic carcinoma with high prevalence of c-kit mutation ...
Passalacqua R. +5 more
core +1 more source
Extracellular Vesicles in Dermatology: Where Are We and What Lies Ahead?
ABSTRACT Extracellular vesicles (EVs) have emerged as key players in skin biology, mediating intercellular communication across diverse physiological and pathological contexts. In this review, we critically assess the current understanding of EVs in dermatology, highlighting their roles in skin homeostasis, ageing, inflammation, wound healing and ...
Ines Martic +14 more
wiley +1 more source
Genetic testing considerations for hereditary duodenopancreatic neuroendocrine tumors
Abstract The incidence of duodenal and pancreatic neuroendocrine tumors (dpNETs) has increased substantially in recent years. These tumors may be due to syndromic hereditary predisposition syndromes: multiple endocrine neoplasia type 1 (MEN1) or 4 (MEN4), Von Hippel–Lindau disease (VHL), neurofibromatosis type 1 (NF1), or tuberous sclerosis complex ...
Théo Charnay +13 more
wiley +1 more source
NUT Midline Carcinoma Masquerading As a Thymic Carcinoma
Thymic carcinomas are rare tumors that arise from the epithelium of the thymus gland and characterized by cytologic atypia, invasiveness, and high risk of relapse and death.1–3 The current WHO schema recognizes at least 11 histologic subtypes.4–7 ...
Loehrer, Patrick J., Sr. +3 more
core +1 more source
Thymic Carcinoma: Current Staging Does Not Predict Prognosis
Background: Thymic carcinomas are currently staged by Masaoka classification, a staging system for thymomas. We retrospectively evaluated surgical patients with thymic carcinoma to determine prognostic factors and to evaluate the usefulness of Masaoka ...
Ginsberg, Robert J. +6 more
core +1 more source
Thymic lymphoepithelial carcinoma (TLEC) is a primary thymic carcinoma that accounts for about 14% of all thymic epithelial tumors and is classified into 14 types.
Kenji Kimura +7 more
core +1 more source

