Results 91 to 100 of about 695,872 (210)

Nonlinear Aging of the Human TCR Repertoire Is Influenced by Sex, CMV, and Cancer

open access: yesAging Cell, Volume 25, Issue 11, November 2026.
Aging is associated with a nonlinear decline in peripheral blood TCR repertoire diversity, with an accelerated decline after ~50 years, while sex, CMV infection, and cancer further shape TCR diversity. The age‐associated decrease in diversity was accompanied by shifts in clonal and T cell subtype composition.
Naja Lange   +9 more
wiley   +1 more source

Thymic carcinoma associated with Sjögren's syndrome and syndrome of inappropriate antidiuretic hormone

open access: yes, 2011
Thymomas are thymic epithelial tumors. The term thymoma has been customarily restricted to those neoplasms arising from or exhibiting differentiation toward thymic epithelial cells.
張金池;張逸良;李元麒   +1 more
core   +1 more source

Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar

open access: yesAging Cell, Volume 25, Issue 11, November 2026.
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley   +1 more source

Development of the International Thymic Malignancy Interest Group International Database: An Unprecedented Resource for the Study of a Rare Group of Tumors

open access: yes, 2014
: Background: Our knowledge of thymic malignancies has largely been derived from small, single-institution series. Recognition of the need for broad collaboration led to the creation of the International Thymic Malignancy Interest Group (ITMIG) and the ...
Ahmad, Usman   +4 more
core  

When a thymic carcinoma " becomes" a GIST

open access: yes, 2013
Thymic carcinoma (TC) is a rare intrathoracic malignancy that it can be invasive and refractory to conventional treatment. Comprehensive genomic analysis evidenced a molecularly distinct subset of thymic carcinoma with high prevalence of c-kit mutation ...
Passalacqua R.   +5 more
core   +1 more source

Extracellular Vesicles in Dermatology: Where Are We and What Lies Ahead?

open access: yesExperimental Dermatology, Volume 35, Issue 11, November 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as key players in skin biology, mediating intercellular communication across diverse physiological and pathological contexts. In this review, we critically assess the current understanding of EVs in dermatology, highlighting their roles in skin homeostasis, ageing, inflammation, wound healing and ...
Ines Martic   +14 more
wiley   +1 more source

Genetic testing considerations for hereditary duodenopancreatic neuroendocrine tumors

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract The incidence of duodenal and pancreatic neuroendocrine tumors (dpNETs) has increased substantially in recent years. These tumors may be due to syndromic hereditary predisposition syndromes: multiple endocrine neoplasia type 1 (MEN1) or 4 (MEN4), Von Hippel–Lindau disease (VHL), neurofibromatosis type 1 (NF1), or tuberous sclerosis complex ...
Théo Charnay   +13 more
wiley   +1 more source

NUT Midline Carcinoma Masquerading As a Thymic Carcinoma

open access: yes, 2016
Thymic carcinomas are rare tumors that arise from the epithelium of the thymus gland and characterized by cytologic atypia, invasiveness, and high risk of relapse and death.1–3 The current WHO schema recognizes at least 11 histologic subtypes.4–7 ...
Loehrer, Patrick J., Sr.   +3 more
core   +1 more source

Thymic Carcinoma: Current Staging Does Not Predict Prognosis

open access: yes, 1998
Background: Thymic carcinomas are currently staged by Masaoka classification, a staging system for thymomas. We retrospectively evaluated surgical patients with thymic carcinoma to determine prognostic factors and to evaluate the usefulness of Masaoka ...
Ginsberg, Robert J.   +6 more
core   +1 more source

Thymic Lymphoepithelial Carcinoma Associated with Epstein-Barr Virus: Experiences and Literature Review

open access: yes, 2021
Thymic lymphoepithelial carcinoma (TLEC) is a primary thymic carcinoma that accounts for about 14% of all thymic epithelial tumors and is classified into 14 types.
Kenji Kimura   +7 more
core   +1 more source

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