Radiation-induced myeloid leukemia in murine models. [PDF]
, 2014 The use of radiation therapy is a cornerstone of modern cancer treatment. The number of patients that undergo radiation as a part of their therapy regimen is only increasing every year, but this does not come without cost.
Davoren, Michael +2 more
core +2 more sources
Synchronous Bilateral Breast Cancer and Thymoma: A Rare Case of Multiple Primary Malignancies
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Synchronous bilateral breast cancer and thymoma is rare, requiring vigilant surveillance and multidisciplinary management. This case highlights the importance of distinguishing multiple primary malignancies from metastases, emphasizing tailored multimodal therapy and long‐term follow‐up to address immune dysregulation and cancer predisposition.
Gholamreza Toogeh +5 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT We report a rare case of thymic metastasis of ovarian serous carcinoma. A 72‐year‐old woman who had undergone surgery for low‐grade serous carcinoma of the ovary and had been free of disease for 25 years was noted to have rising CA‐125 levels. Further workup revealed a mediastinal mass on imaging.
Nicole Fye +3 more
wiley +1 more source
Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia. [PDF]
, 2018 The role of Hedgehog signaling in normal and malignant T-cell development is controversial. Recently, Hedgehog pathway mutations have been described in T-ALL, but whether mutational activation of Hedgehog signaling drives T-cell transformation is unknown,
A Dagklis +54 more
core +1 more source
A Rare Giant Pleural Thymoma in Posterior Mediastinum. [PDF]
, 2012 Thymoma is an epithelial neoplasm of the thymus, which commonly lies in the anterior mediastinum. Unusually, thymomas can also be found in other locations. Surgical excision, when feasible, appears to provide good results. We encountered a rare case of a
Kalloli, M +3 more
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The influence of season, photoperiod, and pineal melatonin on immune function. [PDF]
, 1995 In addition to the well-documented seasonal cycles of mating and birth, there are also significant seasonal cycles of illness and death among many animal populations.
Demas, G +3 more
core +1 more source
Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard [PDF]
, 2018 Purpose: Aim of the study was to: 1) present MDCT characteristics of different mediastinal mass lesions, 2) estimate proportion of benign and malignant mediastinal mass lesions based on MDCT findings, and 3) find out the diagnostic accuracy with ...
Jaipal, Usha +3 more
core +1 more source
Age-related changes in blood-brain barrier integrity in C57BL/6J mice [PDF]
, 2013 The blood-brain barrier (BBB) is formed by the endothelial cells of the brain microvasculature, which control the molecular traffic between the blood and brain to maintain the neural ...
Romero, I. A., Saffrey, M. J., Wang, C.
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Ectopic Cervical Thymoma:A Case Report with 18F-fluorodeoxyglucose Positron Emission Tomography Findings [PDF]
, 2012 Ectopic thymoma is considered to arise from ectopic thymus tissue deposited as a result of the abnormal mislocalization of thymus tissue during the embryonic stage. An 86-year-old man visited our hospital with chief complaints of hoarseness and a mass in
Doihara, Hiroyoshi +7 more
core +1 more source
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
, 2020 Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima +18 more
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