Results 71 to 80 of about 695,872 (210)

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang   +4 more
wiley   +1 more source

Trends in the incidence of thymoma, thymic carcinoma, and thymic neuroendocrine tumor in the United States.

open access: yesPLoS ONE, 2019
This study aimed to identify the trends in the incidence of thymic cancer, i.e., thymoma, thymic carcinoma, and thymic neuroendocrine tumor, in the United States.
Chun-Hsiang Hsu   +5 more
doaj   +1 more source

S‐1 plus cisplatin with concurrent radiotherapy for locally advanced thymic carcinoma: Study protocol of LOGIK1605/JART‐1501

open access: yesThoracic Cancer, 2020
Thymic carcinoma is a rare epithelial tumor of the thymus with a poor prognosis, and multimodal approaches are important for its treatment. Recently, a number of studies have indicated that S‐1 treatment is effective against thymic carcinoma.
Minoru Fukuda   +13 more
doaj   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

Carcinoma tímico: a propósito de um caso clínico

open access: yesRevista Portuguesa de Pneumologia, 2000
RESUMO: Os autores apresentam um caso clinico de carcinoma timico, num bomem de 57 anos, préviamente saudável, que foi enviado á consulta externa de Pneumologia do Hospital de S. João.
Iolanda Mota   +3 more
doaj   +1 more source

Immunohistochemical Characterisation of Mismatch Repair Proteins in Feline Cancers: A Pilot Study Using Validated Cross‐Reactive Antibodies

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT DNA mismatch repair (MMR) deficiency is a clinically important biomarker in human oncology, yet its relevance in feline neoplasia remains poorly understood due to limited characterisation and the absence of validated reagents. In this study, we established a practical immunohistochemistry (IHC) approach for evaluating feline MMR proteins by ...
Shoma Nishibori   +7 more
wiley   +1 more source

Paraneoplastic dermatomyositis as presentation of thymic carcinoma

open access: yes, 2013
Thymic carcinomas are very rare and heterogeneous groups of anterior mediastinum neoformations with an extremely aggressive behavior. Often, the diagnosis is made in the advanced stages.
Andrea Dell’Amore   +11 more
core   +1 more source

Radiotherapy for Thymic Carcinoma: Adjuvant, Inductive, and Definitive [PDF]

open access: yes, 2014
Although historically thymoma and thymic carcinoma have been treated surgically, radiation therapy also has an important role, either as postoperative therapy to reduce the risk of mediastinal recurrence or as part of definitive treatment for patients ...
Ritsuko Komaki   +3 more
core   +1 more source

Durable Response to Lenvatinib in Platinum-Refractory Metastatic High-Grade Thymic Mucoepidermoid Carcinoma: A Case Report

open access: yesJTO Clinical and Research Reports
Thymic mucoepidermoid carcinoma (MEC) is a rare thymic carcinoma subtype. Current metastatic thymic carcinoma guidelines recommend first-line platinum-based chemotherapy.
Noa Amin, PhD, MRCP   +5 more
doaj   +1 more source

Cancer‐associated fibroblast heterogeneity across solid and haematological malignancies: Lessons from colorectal cancer and multiple myeloma

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend CAF origins and plasticity give rise to distinct phenotypes with immunosuppressive functions in colorectal cancer and multiple myeloma. These distinct CAF phenotypes contribute to immunosuppressive tumour microenvironments through ECM remodelling, cytokine signalling and immune regulation.
Hui Mo   +4 more
wiley   +1 more source

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