Results 71 to 80 of about 26,298 (212)
Small, EarlyView.Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley +1 more source
Relationship of possible biomarkers with malignancy of thymic tumors: a meta-analysis
BMC Cancer, 2020 Background Role of biomarkers for promotion of tumor proliferation (BPTPs) and for promotion of apoptosis (BPAs) in thymic malignant tumors is still unclear.
Huilan Zeng +7 more
doaj +1 more source
Cancer Science, EarlyView.Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley +1 more source
Thymic carcinoma: A rare cancer requiring special attention [PDF]
, 2011 SummaryThymic carcinoma is a rare but highly aggressive, easily metastasizing cancer derived from thymic epithelial cells and has a very poor prognosis. Unlike thymoma, which is usually found because it is associated with paraneoplastic syndrome, thymic ...
Yau-Lin Tseng, Tseng, Yau-Lin
core +1 more source
Salvage surgery for stage IVa thymic carcinoma combined with aortic arch resection – case report
Journal of Cardiothoracic Surgery, 2020 Background Although complete surgical resection of thymic carcinoma is a prognostic factor, extended surgery combined with a major blood vessel procedure remains controversial because of the increased risk of mortality.
Hiroyuki Yamato +6 more
doaj +1 more source
MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy
Cancer Science, EarlyView.MTAP deletion creates a therapeutically actionable metabolic vulnerability through MTA accumulation and PRMT5 dependency. This review summarizes the biochemical basis of MTAP‐directed synthetic lethality, emerging PRMT5/MAT2A inhibitors, clinicogenomic features of MTAP‐deleted tumors, and future strategies for precision oncology.
Hiroaki Ikushima, Hidenori Kage
wiley +1 more source
Prognostic Factors of Thymic Carcinoma [PDF]
, 2017 Background: Thymic carcinoma is a rare malignant disease with sparse data for treatment and prognosis. We intended to investigate the prognostic factors of thymic carcinoma.
박인규, 김대준, 정경영
core
Thymic Carcinoma: Current Staging Does Not Predict Prognosis [PDF]
, 1998 Background: Thymic carcinomas are currently staged by Masaoka classification, a staging system for thymomas. We retrospectively evaluated surgical patients with thymic carcinoma to determine prognostic factors and to evaluate the usefulness of Masaoka ...
Ginsberg, Robert J. +6 more
core +1 more source
JTO Clinical and Research ReportsThymic mucoepidermoid carcinoma (MEC) is a rare thymic carcinoma subtype. Current metastatic thymic carcinoma guidelines recommend first-line platinum-based chemotherapy.
Noa Amin, PhD, MRCP +5 more
doaj +1 more source
Thoracic Cancer, 2020 Thymic carcinoma is a rare epithelial tumor of the thymus with a poor prognosis, and multimodal approaches are important for its treatment. Recently, a number of studies have indicated that S‐1 treatment is effective against thymic carcinoma.
Minoru Fukuda +13 more
doaj +1 more source