Results 121 to 130 of about 4,567,849 (254)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Residual cell types, molecular expression profiles and quality assessment of in vitro cultured human thymic slices

陆军军医大学学报
Objective‍　‍‍To analyze the composition and function of residual cells in pre-transplantation human thymic slices by single-cell transcriptomics sequencing (scRNA-seq), and established a quality assessment method for thymic slices based on the expression
GUAN Wanqing, LUO Guihua, HAN Jingxuan
doaj   +1 more source

Large-Scale Isolation of Mouse Thymic Epithelial Cells. [PDF]

Methods Mol Biol, 2023
Ohigashi I, Matsuda-Lennikov M, Takahama Y.   +2 more
europepmc   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development. [PDF]

Sci Adv, 2023
Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A.   +18 more
europepmc   +1 more source

Antiresorptive therapy influence on peri‐implant diseases: Clinical implications and osteoimmunological perspectives

Periodontology 2000, EarlyView.
Abstract Background/Aim Antiresorptive therapy represents a cornerstone in the management of osteoporosis and cancer‐related bone disease through suppression of osteoclast‐mediated bone resorption. As implant therapy becomes more common in aging populations, clinicians increasingly encounter patients receiving these medications, thus making their ...
Emilio A. Cafferata, Frank Schwarz, Reinhard Gruber   +2 more
wiley   +1 more source

Comprehensive Transcriptomic Analysis for Thymic Epithelial Cells of Aged Mice and Humans. [PDF]

Immune Netw, 2023
Lee S, Song SG, Chung DH.
europepmc   +1 more source

Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells. [PDF]

Sci Immunol, 2023
Taves MD, Donahue KM, Bian J, Cam MC, Ashwell JD.   +4 more
europepmc   +1 more source

Immunohistochemical Characterisation of Mismatch Repair Proteins in Feline Cancers: A Pilot Study Using Validated Cross‐Reactive Antibodies

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT DNA mismatch repair (MMR) deficiency is a clinically important biomarker in human oncology, yet its relevance in feline neoplasia remains poorly understood due to limited characterisation and the absence of validated reagents. In this study, we established a practical immunohistochemistry (IHC) approach for evaluating feline MMR proteins by ...
Shoma Nishibori, Masashi Sakurai, Yumiko Kagawa, Kazuo Nishigaki, Takayuki Nakagawa, Sakuya Inanaga, Masaya Igase, Takuya Mizuno   +7 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source