Results 21 to 30 of about 10,319 (186)
Haematologica, 2016 Thymic stromal lymphopoietin (TSLP) stimulates in vitro proliferation of human fetal B-cell precursors. However, its in vivo role during normal human B lymphopoiesis is unknown.
Olivia L. Francis +22 more
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Thymic stromal lymphopoietin and allergic disease [PDF]
Journal of Allergy and Clinical Immunology, 2012 The importance of the epithelium in initiating and controlling immune responses is becoming more appreciated. For example, allergen contact first occurs at mucosal sites exposed to the external environment, such as the skin, airways, and gastrointestinal tract.
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Acta Dermato-Venereologica, 2019 Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong +9 more
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Thymic stromal lymphopoietin and the pathophysiology of atopic disease [PDF]
Expert Review of Clinical Immunology, 2009 Thymic stromal lymphopoietin (TSLP) is an IL-7-related cytokine expressed predominantly by barrier epithelial cells. TSLP is a potent activator of several cell types, including myeloid-derived dendritic cells, monocytes/macrophages and mast cells. Recent studies have revealed an important role for TSLP in the initiation and progression of allergic ...
Michael M, Miazgowicz +3 more
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Lignans from Machilus thunbergii as Thymic Stromal Lymphopoietin Inhibitors
Molecules, 2021 Thymic stromal lymphopoietin (TSLP) plays an important role in the pathophysiology of various allergic diseases that are mediated by T helper cell type-2 (Th2) responses, including asthma and atopic dermatitis.
Hyeji Shin +4 more
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Thymic Stromal Lymphopoietin Is Produced by Dendritic Cells [PDF]
The Journal of Immunology, 2011 Abstract Thymic stromal lymphopoietin (TSLP) is a type 1 cytokine that contributes to lymphopoiesis and the development of asthma and atopic dermatitis. TSLP acts on multiple lineages, including dendritic cells (DCs), T cells, NKT cells, eosinophils, and mast cells, mediating proliferation and survival and linking innate and adaptive ...
Mohit, Kashyap +4 more
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Exacerbation of Allergic Diseases by Chemicals: Role of TSLP
Journal of Pharmacological Sciences, 2014 Environmental chemicals, such as cigarette smoke and diesel exhaust, have been reported as risk factors that exacerbate allergic diseases. However, the exacerbation mechanisms induced by these chemicals are not yet fully understood.
Ryosuke Segawa, Noriyasu Hirasawa
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Functions of thymic stromal lymphopoietin in immunity and disease [PDF]
Immunologic Research, 2012 Thymic stromal lymphopoietin (TSLP) is an interleukin 7-like cytokine expressed mainly by epithelial cells. Current studies provide compelling evidence that TSLP is capable of activating dendritic cells to promote T helper (Th) 2 immune responses. TSLP has also been shown to directly promote Th2 differentiation of naïve CD4(+) T cell and activate ...
Yanlu, Zhang, Baohua, Zhou
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Elevated Plasma Thymic Stromal Lymphopoietin After Acute Myocardial Infarction
Frontiers in Cardiovascular Medicine, 2022 BackgroundThymic stromal lymphopoietin (TSLP), a distant paralog of the cytokine IL-7, has been shown to be associated with atherosclerosis. However, the effect of plasma TSLP level after acute myocardial infarction (AMI) remains largely unclear.
Yuhao Zhao +7 more
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Thymic Stromal Lymphopoietin: To Cut a Long Story ShortSummary
Cellular and Molecular Gastroenterology and Hepatology, 2017 Thymic stromal lymphopoietin (TSLP) was identified more than 20 years ago as a secreted factor of a mouse thymic stromal cell line; later, a human orthologue was also identified.
Katerina Tsilingiri +2 more
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