Results 111 to 120 of about 12,710 (220)
Difference in the expression of IL-9 and IL-17 correlates with different histological pattern of vascular wall injury in giant cell arteritis [PDF]
, 2015 OBJECTIVE: GCA is a large- and medium-vessel arteritis characterized by a range of histological patterns of vascular wall injury. The aim of this study was to immunologically characterize the various histological patterns of GCA.
ALESSANDRO, Riccardo +10 more
core +2 more sources
World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 124-135, February 2026.ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu +7 more
wiley +1 more source
Thymic Stromal Lymphopoietin (TSLP)
Current allergy and asthma reportsPurpose of the Review: Thymic stromal lymphopoietin (TSLP) is increasingly recognized for its pivotal role in the pathogenesis of various epithelial-driven chronic inflammatory diseases. This review navigates the existing evidence on TSLP, with a particular focus on asthma, before delving into the current understanding of its role in chronic ...
de Corso, Eugenio +8 more
openaire +1 more source
, 2015 Delivering vaccine antigens to mucosal surfaces is potentially very attractive, especially as protection from mucosal infections may be mediated by local immune responses.
Buffa, V +8 more
core +2 more sources
Distinct Roles of IL‐4, IL‐13, and IL‐22 in Human Skin Barrier Dysfunction and Atopic Dermatitis
Allergy, Volume 81, Issue 2, Page 480-497, February 2026.This study reports the distinct effects of IL‐4, IL‐13, and IL‐22 on bio‐stabilized human skin with intact barriers and immune cells. IL‐4, IL‐13, and IL‐22 upregulate inflammatory mediators, disrupt skin barrier integrity, and reciprocally modulate IL‐4Rα and IL‐22Rα1 receptors.
Paolo D'Avino +12 more
wiley +1 more source
Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions
Allergy, Volume 81, Issue 2, Page 326-344, February 2026.ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller +9 more
wiley +1 more source
Monoclonal antibodies in type 2 asthma : a systematic review and network meta-analysis [PDF]
, 2019 Since novel treatments to target eosinophilic inflammation in Type 2 asthma are emerging, we aimed to evaluate and meta-analyze the efficacy of monoclonal antibodies to reduce exacerbation rate.
De Feyter, Silke +4 more
core +1 more source
International Journal of Dermatology, Volume 65, Issue 2, Page 257-272, February 2026.ABSTRACT Mesenchymal stromal cells (MSCs) exert their effects primarily through paracrine signaling via soluble factors and extracellular vesicles (EVs), especially exosomes. These acellular components offer regenerative and immunomodulatory benefits with fewer safety and logistical constraints than cell‐based therapies.
Marcela da Costa Pereira Cestari +2 more
wiley +1 more source
Thymic Stromal Lymphopoietin (TSLP), Its Isoforms and the Interplay with the Epithelium in Allergy and Asthma. [PDF]
Int J Mol Sci, 2023 Smolinska S +3 more
europepmc +1 more source
Genetic and epigenetic studies of atopic dermatitis [PDF]
, 2016 Additional file 2: References.
Donald Y. M. Leung, Lianghua Bin
core +3 more sources