Results 111 to 120 of about 199,261 (304)

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

open access: yesAging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang   +8 more
wiley   +1 more source

Chemical Eluates from Ultra-High Molecular Weight Polyethylene and Fibroblast Proliferation

open access: yesJournal of Orthopaedic Surgery, 2001
Although polyethylene wear particles have been implicated in osteolysis and implant loosening, this study is the first to test whether chemical eluates extracted from ultra-high molecular weight polyethylene (UHMWPE) could also be involved in this ...
Kate Y Wang   +4 more
doaj   +1 more source

Pregnancy in women with mitochondrial disease—A literature review and suggested guidance for preconception and pregnancy care

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, Volume 65, Issue 1, Page 30-36, February 2025.
Mitochondrial donation to reduce the risk of primary mitochondrial disease transmission from mother to child is now permitted under Australian law as part of a clinical trial. The energy demands of pregnancy have the potential to worsen mitochondrial disease symptoms and severity in affected women.
Lisa Hui   +9 more
wiley   +1 more source

Simultaneous Determination of Ten Nucleosides in New Selenium-enriched Bamboo Shoots by HPLC-FP

open access: yesShipin gongye ke-ji
Objective: To establish a method for simultaneous determination of cytosine, uracil, cytidine, hypoxanthine, uridine, thymidine, adenine, guanosine, thymidine and adenosine in different selenium-rich bamboo shoots.
Xinrui QIN   +9 more
doaj   +1 more source

Higher Efficiency of Retrovirus Transduction in the Late Stage of Primary Culture of Hepatocytes from Nontreated than from Partially Hepatectomized Rat

open access: yesCell Transplantation, 1998
The aim of this investigation was to optimize the conditions for gene transduction by a retroviral vector into primary cultured hepatocytes. Because a retrovirus infection is dependent upon the proliferative activity of the target cells, we examined the ...
Shin Enosawa   +5 more
doaj   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

open access: yesAndrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy