Results 141 to 150 of about 576,830 (232)

Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts.

, 2006
Cellular models of mitochondrial thymidine kinase (TK2) deficiency require a reliable method to measure TK2 activity in whole cell extracts containing two interfering deoxyribonucleoside kinases, thymidine kinase 1 (TK1) and deoxycytidine kinase.
PEREZ PEREZ MJ, FRANZOLIN, ELISA, RAMPAZZO, CHIARA, BALZARINI J, BIANCHI, VERA, HERNANDEZ AI   +5 more
core  

Thymidine kinase as a biomarker of chemoresistance in epithelial ovarian cancer using the KELIM model. [PDF]

Front Pharmacol
Lukanović D, Osredkar J, Škof E, Cviič D, Jerin A, Lešnik K, Matjašič M, Meglič L.   +7 more
europepmc   +1 more source

Variant Analysis of the Thymidine Kinase and DNA Polymerase Genes of Herpes Simplex Virus in Korea: Frequency of Acyclovir Resistance Mutations. [PDF]

Viruses, 2023
Hyun J, Lee SK, Kim JH, Cho EJ, Kim HS, Kim JS, Song W, Kim HS.   +7 more
europepmc   +1 more source

Hiding Human Thymidine Kinase 1 from Apc/C-Mediated Destruction by Thymidine Binding

, 2008
Thymidine kinase 1 (TK1) is a key cytosolic enzyme in the salvage pathway for dTTP synthesis. In mitotic exit, human TK1 (hTK1) is degraded via the anaphase-promoting complex/ cyclosome (APC/C)-Cdh1 pathway to limit dTTP production.
柯博元;張益昌;張智芬, KE, PO-YUAN;CHANG, YI-CHANG;CHANG, ZEE- FEN   +1 more
core  

Nucleoside therapy for thymidine kinase 2 deficiency: Long-term outcomes from a Brazilian cohort. [PDF]

J Neuromuscul Dis
Moreno CAM, Fernandes TR, Camelo CG, Keller G, Di Pace F, Dousseau GC, Fonseca ATQSM, Campos ED, Anjos Lança APD, Artilheiro MC, Serafim da Silva AM, Paiva MA, Nascimento A, Zanoteli E.   +13 more
europepmc   +1 more source

Association of thymidine kinase-1 with prostate cancer

Asian Journal of Surgery
Changyi Jiang, Wenting Zhou, Linhui Wang, Changxing Ke   +3 more
doaj   +1 more source

Green silver nanoparticles of Khaya senegalensis as dual inhibitors of viral thymidine kinase and 3 C protease: metabolomics, and computational insights. [PDF]

Sci Rep
El Gizawy HA, El-Aleam RHA, Hassan NH.
europepmc   +1 more source

A monoclonal antibody-based sandwich ELISA for measuring canine Thymidine kinase 1 protein and its role as biomarker in canine lymphoma. [PDF]

Front Vet Sci, 2023
Sharif H, Saellström S, Kolli B, Jagarlamudi KK, Wang L, Rönnberg H, Eriksson S.   +6 more
europepmc   +1 more source

Transforming the natural course of infantile onset thymidine kinase 2 deficiency through early nucleoside replacement therapy. [PDF]

J Neuromuscul Dis
Akinci G, Sardarzada J, Topaloglu H.
europepmc   +1 more source

Mutation and Interaction Analysis of the Glycoprotein D and L and Thymidine Kinase of Pseudorabies Virus. [PDF]

Int J Mol Sci, 2022
Li X, Chen S, Zhang L, Zheng J, Niu G, Yang L, Zhang X, Ren L.   +7 more
europepmc   +1 more source