Results 141 to 150 of about 6,430 (168)

Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase in Bladder Cancer

Urologia Internationalis, 2002
Thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) levels in transitional cell carcinoma of the bladder resected from 38 patients were examined by ELISA. TP levels in high-grade and invasive cancer were significantly higher than those in low-grade and superficial cancer, respectively.
Tatsuo, Iizumi, Kyouichi, Hariu, Mika, Sato, Satoshi, Sato, Hirofumi, Shimizu, Hiroshi, Tomomasa, Takashi, Umeda   +6 more
openaire   +2 more sources

Expression of thymidine phosphorylase and cyclooxygenase-2 in melanoma

Melanoma Research, 2013
Several studies have reported an increase in vascular structures in malignant melanoma. Neovascularization can be enhanced by several factors. Among them, thymidine phosphorylase (TP) and cyclooxygenase-2 (COX-2) have been reported to play a role. The expressions of TP and COX-2 were evaluated trough immunohistochemistry in a series of 78 primary ...
Minisini AM, Pascoletti G, Intersimone D, Poletto E, Driol P, Spizzo R, SCOTT, Cathryn Anne, PUGLISI, Fabio, Fasola G, DI LORETO, Carla   +9 more
openaire   +3 more sources

Localization of thymidine phosphorylase in breast cancer tissue

Medical Molecular Morphology, 2005
Thymidine phosphorylase levels are higher in some human cancer tissues than in adjacent normal tissue. However, the ultrastructural localization of thymidine phosphorylase in cancer tissue has been demonstrated only in advanced gastric and colorectal cancer.
Michiya, Kobayashi, Takeki, Sugimoto, Takehiro, Okabayashi, Ken, Okamoto, Tsutomu, Namikawa, Naoshige, Tochika, Toshiaki, Moriki, Keijiro, Araki   +7 more
openaire   +2 more sources

Substrate specificity of Escherichia coli thymidine phosphorylase

Biochemistry (Moscow), 2007
Substrate specificity of Escherichia coli thymidine phosphorylase to thymidine derivatives modified at 5' -, 3' -, and 2' ,3' - positions of the sugar moiety was studied. Equilibrium and kinetic constants (K(m), K(I), k(cat)) of the phosphorolysis reaction have been determined for 20 thymidine analogs.
N G, Panova, C S, Alexeev, A S, Kuzmichov, E V, Shcheveleva, S A, Gavryushov, K M, Polyakov, A M, Kritzyn, S N, Mikhailov, R S, Esipov, A I, Miroshnikov   +9 more
openaire   +2 more sources

[Thymidine phosphorylase and angiogenesis].

Gan to kagaku ryoho. Cancer & chemotherapy, 2000
Thymidine phosphorylase (TP) is identical to platelet-derived endothelial cell growth factor (PD-ECGF). TP has an angiogenic activity and confers resistance to hypoxia-induced apoptosis on cells. TP expression is correlated with microvessel count, invasion and poor prognosis in many solid tumors.
openaire   +1 more source

[Expression of thymidine phosphorylase in cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology], 2005
To study the thymidine phosphorylase (TP) expression in different types of cancer and its correlation with tumor microvessel density (MVD).The expression of TP and MVD was detected by immunohistochemistry method. In a series of 251 cancer patients there were 48 patients with gastric cancer, 53 with colorectal cancer, 47 with breast cancer, 56 with ...
Li-na, Jiang, Shi-ying, Yu, Hui-hua, Xiong, Meng-xian, Zhang   +3 more
openaire   +1 more source

Thymidine phosphorylase and breast carcinoma.

Anticancer research, 2002
Thymidine phosphorylase (TP), also known as platelet-derived endothelial-cell growth factor (PD-ECGF), is an enzyme that catalyzes the reversible dephosphorylation of thymidine, deoxyguridine and their analogs. TP also has angiogenic properties, although the precise mechanism by which it promotes angiogenesis is not known.
Qifeng, Yang, Goro, Yoshimura, Ichiro, Mori, Takeo, Sakurai, Kennichi, Kakudo   +4 more
openaire   +1 more source

Thymidine phosphorylase

1996
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source

Thymidine Phosphorylase Deficiency

2009
Satish R. Raj, S. R. Wayne Chen, Robert S. Sheldon, Arti N. Shah, Bharat K. Kantharia, Ulrich Salzer, Bodo Grimbacher, Alexander K. C. Leung, Deepak Kamat, Genovefa D. Kolovou, Katherine K. Anagnostopoulou, Dennis V. Cokkinos, Takahiro Shinkai, Rosaline C. M. Quinlivan, Robert Beynon, Thomas Kolter, Ute Schepers, Konrad Sandhoff, Christophe Nicot, Werner Kempf, Reinhard Dummer, Günter Burg, Urban W. Geisthoff, Deborah Bartholdi, Albert Schinzel, Deborah Bartholdi, Albert Schinzel, Deborah Bartholdi, Albert Schinzel, Stefan R. Bornstein, Nenad Blau, Elizabeth Goldmuntz, John-John B. Schnog, Victor E. A. Gerdes, Jacky Bonaventure, Donatus Nohr, Anthony M. Marinaki, Monica Arenas, Robert F. Groff IV, Jason H. Huang, Hugo Ten Cate, Ayalew Tefferi, Han-Mou Tsai, Mofid Ibraheim, Amaj Ikomi, Bob Olsson, Hans Wadenvik, Julian Ilcheff, Hugo Ten Cate, Henri Bounameaux, Marc Righini, Christopher J. Boos, Gregory Y. H. Lip, Hugo Ten Cate, Hugo Ten Cate, Yuval Ramot, Neta Goldschmidt, Abraham Nyska, Hugo Ten Cate, Hugo Ten Cate, Hugo Ten Cate, Hugo Ten Cate, André B. P. Van Kuilenburg, Albert H. Van Gennip*, Alexander K. C. Leung, Christian A. Koch, Nicholas J. Sarlis, Douglas Forrest, Peter Kopp, Seda Sancak, Markus Eszlinger, Ralf Paschke, Seda Sancak, Ralf Paschke, Antonella Fioravanti, Maria Antonietta Mazzei, Giuseppina Coppola, Luca Volterrani, Hans-Peter Zenner, Ilse Maria Zalaman, Ulrike Schumacher, Ingo B. Autenrieth, Nitin Wadhani, Hari Red, Shah Azmoon, Harpreet Singh, Bramah N. Singh, David W. Brown, Tal Geva, Claudio Guarneri, Francesco Borgia, Mario Vaccaro, Norbert Müller, Jürgen Kohlhase, Andreas Erhardt, Freddy Mboti, Karina Yazdanbakhsh, Millicent Sutton, Jan-Luuk Hillebrands, Roel de Weger, Jan Rozing, Linda Leatherbury, Cecilia Lo, Jutta Engel, Elan D. Louis, Fabrizio Guarneri, Mario Vaccaro, Mark Berneburg, Thomas Schwarz, Gabriele A. Krombach, Alfonso Baldi, Koichiro Niwa, Sefik Guran, Trevor J. Pugh, Marco A. Marra, Deborah Bartholdi, Albert Schinzel, John Wolstenholme, Deborah Bartholdi, Albert Schinzel, Alexander K. C. Leung, Hardally R. Hegde, Joachim Richter, Hiroyuki Yamagishi, Keiichi Fukuda, Maximilian Ledochowski, Dietmar Fuchs, Pushpa Agrawal, Md. Suhail Alam†, Saurabh K. Garg†, Ralf Wienecke, Giovambattista Capasso, Mauro Bernardi, Franco Trevisani, Kimitoshi Nakamura, Shiro Matsumoto, Hiroshi Mitsubuchi, Fumio Endo, Kimitoshi Nakamura, Shiro Matsumoto, Hiroshi Mitsubuchi, Fumio Endo, Kimitoshi Nakamura, Shiro Matsumoto, Hiroshi Mitsubuchi, Fumio Endo   +145 more
openaire   +3 more sources

Thymidine Kinase (thymidine phosphorylase)

2008
openaire   +1 more source