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Thymidine Phosphorylase Expression in Gastric Cancer Tissues is Associated with Thrombocytosis but not with Serum Thymidine Phosphorylase Concentration

Thymidine Phosphorylase Expression in Gastric Cancer Tissues is Associated with Thrombocytosis but not with Serum Thymidine Phosphorylase Concentration
ORIGINAL ARTICLE Background: The relationship of thymidine phosphorylase (TP) expression and patient outcomes has been investigated in various cancers. This study investigated the association of TP expression, serum TP, and platelet counts in patients with gastric cancer. Methods: A series of 77 patients with gastric adenocarcinoma were enrolled in the
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Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study. [PDF]

Sci Rep, 2019
Zaman K, Rahim F, Taha M, Wadood A, Shah SAA, Ahmed QU, Zakaria ZA.   +6 more
europepmc   +1 more source

Thymidine phosphorylase: A potential new target for treating cardiovascular disease. [PDF]

Trends Cardiovasc Med, 2018
Li W, Yue H.
europepmc   +1 more source

Natural compounds as angiogenic enzyme thymidine phosphorylase inhibitors: In vitro biochemical inhibition, mechanistic, and in silico modeling studies. [PDF]

PLoS One, 2019
Javaid S, Shaikh M, Fatima N, Choudhary MI.   +3 more
europepmc   +1 more source

Mitochondrial Neurogastrointestinal Encephalomyopathy: Novel Pathogenic Mutation in Thymidine Phosphorylase Gene in a Patient from Cape Verde Islands. [PDF]

Case Rep Neurol Med, 2019
Falcão de Campos C, Oliveira Santos M, Roque R, Conceição I, de Carvalho M.   +4 more
europepmc   +1 more source

Thymidine phosphorylase promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect. [PDF]

Cell Death Dis, 2019
Zhang Q, Qin Y, Zhao J, Tang Y, Hu X, Zhong W, Li M, Zong S, Li M, Tao H, Zhang Z, Chen S, Chen S, Liu H, Yang L, Zhou H, Liu Y, Sun T, Yang C.   +18 more
europepmc   +1 more source

Thymidine Phosphorylase Expression and Microvascular Density Correlation Analysis in Canine Mammary Tumor: Possible Prognostic Factor in Breast Cancer. [PDF]

Front Vet Sci, 2019
Zizzo N, Passantino G, D'alessio RM, Tinelli A, Lopresti G, Patruno R, Tricarico D, Maqoud F, Scala R, Zito FA, Ranieri G.   +10 more
europepmc   +1 more source

The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells. [PDF]

Gastric Cancer, 2019
Mori R, Yoshida K, Futamura M, Suetsugu T, Shizu K, Tanahashi T, Tanaka Y, Matsuhashi N, Yamaguchi K.   +8 more
europepmc   +1 more source

Choice of Capecitabine or S1 in Combination with Oxaliplatin based on Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase Expression Status in Patients with Advanced Gastric Cancer. [PDF]

J Gastric Cancer, 2019
Xu R, He X, Wufuli R, Su Y, Ma L, Chen R, Han Z, Wang F, Liu J.   +8 more
europepmc   +1 more source

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Catabolism of thymidine in human blood platelets purification and properties of thymidine phosphorylase

Nucleic Acids and Protein Synthesis, 1981
A pyrimidine nucleoside phosphorylase was partially purified from human blood platelets. The purified enzyme, as well as crude enzyme preparations, catalyses the phosphorolysis of thymidine and deoxyuridine, but not of uridine, and is able to catalyse direct pentosyl transfer from these deoxyribonucleosides to uracil or thymine; this enzyme has the ...
G Razaka, C Desgranges
exaly   +3 more sources