Results 161 to 170 of about 74,896 (329)

Enhanced Selectivity by Planar Hyper‐Coordinate Transition Metals for Biosensing

open access: yesAdvanced Theory and Simulations, Volume 9, Issue 1, January 2026.
This study proposed a possible route to enhance selectivity via the emerging 2D materials with planar hyper‐coordinate transition metals, which suppressed the multienzyme‐like activity of transition metals. And we verified our strategy using density functional theory calculations of biomolecule adsorption on planar hyper‐coordinate ScCN3B6 and non ...
Zihan Zhang, Rajeev Ahuja, Wei Luo
wiley   +1 more source

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu   +20 more
wiley   +1 more source

Studies on ultrasound-induced reactions in aqueous thymine solutions.

open access: bronze, 1984
Keisuke Makino   +3 more
openalex   +2 more sources

DNA methylation patterns of candidate genes regulated by thymine DNA glycosylase in patients with TP53 germline mutations [PDF]

open access: gold, 2015
Marcos Fraga Fortes   +5 more
openalex   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

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