Results 241 to 250 of about 60,531 (292)

Facially-selective thymine thymine photodimerization in TTT triads

Photochemical & Photobiological Sciences, 2012
Irradiation of alkane-linked DNA hairpins possessing TTT steps with flanking purine bases yields products identified as the cis-syn (2 + 2) dimers formed between the central thymine and its 3'- and 5'-neighbors. Selective formation of the 3'-dimer is attributed to ground state conformational effects and electron transfer quenching by purine bases.
Prakash P, Neelakandan, Zhengzheng, Pan, Mahesh, Hariharan, Frederick D, Lewis   +3 more
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Electronic Structure of Thymine

The Journal of Chemical Physics, 1970
The electronic structures of the ground and low-lying excited states of thymine and the anions 1-HT− and 3-HT−, derived by removing a proton from nitrogen atom N3 and N1, respectively, have been described by all-electron all-integral LCAO–SCF calculations using Gaussian basis functions.
L C, Snyder, R G, Shulman, D B, Neumann
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Radioimmunoassay of a Thymine Glycol

Radiation Research, 1982
A sensitive and specific radioimmunoassay for 5,6-dihydroxy-5,6-dihydrothymine (thymine glycol) was developed. As little as 4 femtomoles of thymine glycol can be detected in ${\rm O}_{{\rm s}}{\rm O}_{4}\text{-treated}$ DNA. Unmodified DNA cross-reacts only at the highest concentrations.
G J, West, I W, West, J F, Ward
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Reduction of thymine by leukocytes

Biochemical Genetics, 1968
The maximal activity of the dihydrothymine dehydrogenase of fractions of human blood was found in leukocytes, especially in the supernatant after centrifugation of homogenates at 100,000 × g in the course of isolation of the cell components. The dihydrothymine dehydrogenase from human and pig leukocytes was purified tenfold with a yield of activity of ...
H W, Goedde, R, Hoffbauer, K G, Blume
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Photochemistry of thymine dimers

Journal of Molecular Biology, 1962
The extinction coefficient and the quantum yield of photodissociation of a thymine dimer obtained by irradiating thymine in frozen solution have been measured for the range 225 to 289 mμ. The dinucleotides di(thymidine-5′-phosphate) (pTpT), cyclic dithymidylic acid Download : Download full-size image and thymidylyl-(5′−3′)-thymidine ...
H E, JOHNS, S A, RAPAPORT, M, DELBRUECK
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PHOTOSENSITIZED DIMERIZATION OF THYMINE

Photochemistry and Photobiology, 1970
Abstract— In contrast with previous reports from other laboratories, four isomeric dimers were isolated from the photochemical reaction of thymine sensitized by either acetone or propiophenone. Product analyses, made by use of nuclear magnetic resonance spectroscopy, showed that the distribution of dimers is dependent on the character of the solvent ...
B H, Jennings, S C, Pastra, J L, Wellington   +2 more
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PROPERTIES OF THYMINE DIMERS

Photochemistry and Photobiology, 1969
Abstract— The photochemical and chemical properties of the four dimers of thymine have been studied. The extinction coefficients, reversal cross‐sections and quantum yields for reversal are presented as a function of wavelength in the range 200–289 nm.
M A, Herbert, J C, LeBlanc, D, Weinblum, H E, Johns   +3 more
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The permanganate oxidation of thymine

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1970
Abstract 1. Mild permanganate oxidation of thymine yielded cis-thymine glycol (cis-5,6-dihydroxy-5,6-dihydrothymine) and 5-hydroxy-5-methylbarbituric acid. Under certain reaction conditions, only these two compounds were the products of the reaction. 2.
S, Iida, H, Hayatsu
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Conical Intersections in Thymine

The Journal of Physical Chemistry A, 2006
The mechanisms which are responsible for the radiationless deactivation of the npi* and pipi* excited singlet states of thymine have been investigated with multireference ab initio methods (the complete-active-space self-consistent-field (CASSCF) method and second-order perturbation theory with respect to the CASSCF reference (CASPT2)) as well as with ...
Serhiy, Perun, Andrzej L, Sobolewski, Wolfgang, Domcke   +2 more
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Determination of laser-induced thymine–thymine dimer in DNA by LC

Journal of Pharmaceutical and Biomedical Analysis, 2002
A new simple and selective high-performance liquid chromatography (HPLC) method has been developed for the determination of thymine-thymine (T-T) dimer in deoxyribonucleic acid (DNA) for the study of relationship between the yield of T-T dimer and laser irradiation conditions. The HPLC method is not disturbed by other hydrolysate formed in DNA with the
Lingxia, Zhang, Yuzhu, Hu
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