Results 251 to 260 of about 60,531 (292)

Context-Dependent Photodimerization in Isolated Thymine−Thymine Steps in DNA

Journal of the American Chemical Society, 2008
The effect of 280 nm irradiation on a family of synthetic DNA hairpins possessing an alkane linker connecting a six-base pair stem having a single T-T step located at different positions within the hairpin has been investigated. A single adduct assigned to the product of 2+2 dimerization is obtained except in the case of a T-T step located adjacent to ...
Mahesh, Hariharan, Frederick D, Lewis
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Selectivity for thymine over 5-bromouracil by a thymine-requiring bacterium

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966
Abstract The relative incorporation of thymine and its analogue, 5-bromouracil, into the DNA of a thymine-requiring bacterium was studied under a variety of conditions. Exponentially growing cultures of Escherichia coli strain TAU-bar were transferred to media containing defined amounts of thymine and 5-bromouracil.
P, Hackett, P, Hanawalt
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Interconversion of thymine and thymidine in a thymine requiring strain of Bacillus subtilis

Biochemical and Biophysical Research Communications, 1975
In a B. subtilis Thy− strain, thymidine is rapidly converted into thymine and, at the steady state, the pool size of thymidine is very small as compared to that of thymine. Consequently when such strain is used for pulse incorporation experiments with labelled thymidine paradoxical results are obtained.
MASTROMEI, GIORGIO, S. RIVA
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THE ISOLATION OF THYMOPOIETIN (THYMIN)*

Annals of the New York Academy of Sciences, 1975
The isolation from bovine thymus of two closely related polypeptides, thymopoietin I and II, is described. These are considered to be thymic hormones, which physiologically induce the differentation of prothymocytes to thymocytes within the thymus.
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Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase ζ

Science, 1996
The REV3 and REV7 genes of the yeast Saccharomyces cerevisiae are required for DNA damage-induced mutagenesis. The Rev3 and Rev7 proteins were shown to form a complex with DNA polymerase activity. This polymerase replicated past a thymine-thymine cis-syn
J R, Nelson, C W, Lawrence, D C, Hinkle
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DNA base stacking: The stacked uracil/uracil and thymine/thymine minima

Journal of Computational Chemistry, 2012
AbstractThe potential energy surfaces of stacked uracil dimer (U/U) and stacked thymine dimer (T/T) have been explored at the counterpoise (CP)‐corrected M06‐2X/6‐31+G(d) level of theory, in the gas phase and in solution (with water and, for U/U, 1,4‐dioxane as the solvents) modeled by a continuum solvent using the polarizable continuum model ...
Ruairidh S. Hunter, Tanja Van Mourik
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On the nature of thymine photoproduct

Biochimica et Biophysica Acta, 1961
Abstract Frozen aqueous solutions of thymine and N,N′-dimethylthymine have been irradiated at 2537 A to yield two dimers from N,N′-dimethylthymine and a single dimer from thymine. In all cases irradiation of the dimer in liquid aqueous solution at 2537 A causes reversion to the monomer.
D L, WULFF, G, FRAENKEL
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ESR Study of the Thymine Anion Radical in a Single Crystal of Thymine Monohydrate

International Journal of Radiation Biology, 1990
ESR spectroscopy was used to study free radicals in an irradiated single crystal of thymine monohydrate at 77 K. At low microwave power (20 microW), a broad doublet is found to be super-imposed on the well known resonance patterns of the 5-yl and 7-yl radicals. The doublet spectrum has been analysed as a difference spectrum.
Kabiljo, Zvjezdana, Sanković, Krešimir, Herak, Janko   +2 more
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Quantitative extraction of thymine-thymine dimer from a large excess of thymine by preparative liquid chromatography

Journal of Chromatography A, 1989
Abstract Extremely small amounts of thymine-thymine dimer can be extracted from thymine solutions using overloaded elution and shaving a narrow fraction at the front of the overloaded, later eluting thymine band. A two- or three-step procedure, involving the concentration and reinjection of the collected fraction, permits the preparation of solutions
A.M. Katti, R. Ramsey, G. Guiochon
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Thymine starvation by inhibition of uptake and synthesis of thymine-compounds in Tetrahymena

Experimental Cell Research, 1968
Abstract In Tetrahymena populations, which are heat-synchronized in a proteosepeptone, liver medium, addition after the heat-shocks of a folic acid analogue, 0.05 mM methotrexate (M), plus 5 mM uridine (U), inhibit the second synchronous division in most cells. This inhibition can be specifically overcome with thymidine.
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