Results 111 to 120 of about 46,331 (223)

TNF‑α Gene Polymorphisms as Determinants of Alloantibody Emergence in Hemophilia: A Systematic Review and Meta‐Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Inhibitor development remains one of the most serious complications of replacement therapy in patients with hemophilia. Tumour necrosis factor‐alpha (TNF‐α) is a key pro‐inflammatory cytokine, and its genetic variants have been implicated in immune‐related conditions.
Alessandra Faustino da Conceição Bezerra, Natã Abner Andrade Carito de Sousa, Suely Meireles Rezende, Renan Pedra de Souza   +3 more
wiley   +1 more source

Computer Program for Primer Design for Loop-Mediated Isothermal Amplification (LAMP)

Advanced Engineering Research
Introduction. To date, numerous methods of nucleic acid amplification have been proposed, and each method has a number of advantages and disadvantages. One of the most popular methods is Loop-mediated isothermal AMPlification (LAMP).
L. U. Akhmetzianov
doaj   +1 more source

Integrative taxonomy reveals four new species of the armoured catfish genus Pareiorhina (Siluriformes: Loricariidae) from the upper Paraná River basin, Brazil

Journal of Fish Biology, EarlyView.
Abstract Four new species of the small‐sized armoured catfish genus Pareiorhina are described from mountain ranges in the Grande River drainage, upper Paraná River basin, based on morphological and molecular species delimitation methods. Molecular analyses based on the cytochrome oxidase subunit I (COI) marker recovered Pareiorhina as polyphyletic ...
Pedro L. C. Uzeda, Luana J. Sartori, Axel M. Katz, Felipe P. Ottoni, Wilson J. E. M. Costa, Francisco Langeani, Valter M. Azevedo‐Santos   +6 more
wiley   +1 more source

Single molecule DNA sequencing via transverse electronic transport using a graphene nanopore: A tight-binding approach

, 2016
We report a tight-binding model study of two-terminal graphene nanopore based device, for sequential determination of DNA bases. Using Greens function approach we calculate conductance spectra, I-V response and also the changes in local density of states
Karmakar, S. N., Kundu, Sourav
core  

VERNALIZATION2 alters early tiller development in a facultative spring hexaploid bread wheat

New Phytologist, EarlyView.
Summary An extended period of cold exposure enables the process of vernalization in winter cereals and is important for the synchronised timing of the floral transition. The cereal‐specific floral repressor VERNALIZATION2 (VRN2) has an integral role in vernalization, yet this locus remains poorly characterised in facultative spring hexaploid wheat ...
Dominique Hirsz, Harry Taylor, India Lacey, Wenxue Wu, Adam Gauley, Laura Dixon   +5 more
wiley   +1 more source

Deletion mutants of bacteriophage phiX174 [PDF]

, 1972
Mutants of bacteriophage phiX174 have been isolated that are less dense than wild-type phiX particles in CsCl. When mutant viral (+) strand DNA and wild-type complementary (-) strand DNA are hybridized, the resulting duplex molecules have single-stranded
Benbow, Robert M., Sinsheimer, Robert L., Zuccarelli, Anthony J.   +2 more
core  

Identification of a Susceptibility Gene for Xanthomonas oryzae pv. oryzae in Vietnamese Elite Rice (Oryza sativa L.) Cultivar Bacthom 7

Plant Breeding, EarlyView.
ABSTRACT Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of bacterial leaf blight (BLB) disease in rice, exerting a detrimental impact on the yield of various rice cultivars in Vietnam, notably the Bacthom 7 (BT7) variety. Xoo possesses transcription activator‐like effectors (TALEs) which modulate the expression of host genes by specifically ...
Nguyen Duy Phuong, Dong Huy Gioi, Cao Le Quyen, Nguyen Xuan Hung, Ha Hai Yen, Bui Thi Thu Huong, Sebastien Cunnac, Tran Dang Xuan, Pham Xuan Hoi   +8 more
wiley   +1 more source

Balancing Innovation and Ethics

Voices in Bioethics
Photo by CDC on Unsplash ABSTRACT The growth of direct-to-consumer genetic testing promises insight into health risks and ancestral roots. This essay examines how at-home DNA kits empower users to detect potential genetic conditions early, create ...
Anisa Patel
doaj   +5 more sources

Spectroscopic analysis of bacterial photoreactivation

Photochemistry and Photobiology, Volume 101, Issue 2, Page 494-504, March/April 2025.
This study investigates the effectiveness of fluorescence and Raman spectroscopy in detecting bacterial photoreactivation. Fluorescence spectroscopy shows limitations, because the intense fluorescence of tryptophan and tyrosine masks fluorescence emitted by thymine molecules.
Keyvan Khosh Abady, Negar Karpourazar, Arjun Krishnamoorthi, Runze Li, Peter M. Rentzepis   +4 more
wiley   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

Photochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes, Fernanda M. Prado, Helena C. Junqueira, Marisa H. G. Medeiros, Graziella E Ronsein, Jean Cadet, Paolo Di Mascio   +6 more
wiley   +1 more source