Results 21 to 30 of about 46,331 (223)
Structure and mechanism of human DNA polymerase η [PDF]
, 2010 The variant form of the human syndrome xeroderma pigmentosum (XPV) is caused by a deficiency in DNA polymerase eta (Pol eta), a DNA polymerase that enables replication through ultraviolet-induced pyrimidine dimers.
A Alt +66 more
core +2 more sources
Frontiers in Pharmacology, 2023 Background: Baicalein is an active ingredient extracted from the root of S. baicalensis Georgi, which exhibits cardiovascular protection, anti-inflammatory, and anti-microbial properties.
Jing Shi +10 more
doaj +1 more source
Small-angle polarimetry as a technique for identification of nucleotide sequences in bioinformatics [PDF]
Известия Саратовского университета. Новая серия: Физика, 2023 Background and Objectives: The method of identification of symbolic sequences associated with the genetic structure of biological objects using the principles of small-angle polarimetry is considered.
Zimnyakov, Dmitry Aleksandrovich +4 more
doaj +1 more source
Frontiers in Chemistry, 2022 . DNA is often referred to as the “molecule of life” since it contains the genetic blueprint for all forms of life on this planet. The core building blocks composing DNA are deoxynucleotides. While the deoxyribose sugar and phosphate group are ubiquitous,
Anthony Berdis
doaj +1 more source
Double-headed nucleotides introducing thymine nucleobases in the major groove of nucleic acid duplexes [PDF]
Organic & Biomolecular Chemistry, 2015 Four double-headed nucleotides are synthesized via Sonogashira and Suzuki couplings and introduced into nucleic acid duplexes.
Jensen, Michael Dalager +4 more
openaire +4 more sources
A modular self-assembled sensing system for heavy metal ions with tunable sensitivity and selectivity [PDF]
, 2017 Here we describe a self-assembled sensing system composed of three separate modules: gold nano particles, a reporter element, and a recognition element. The gold nanoparticles serve as a multivalent platform for the interaction with both the reporter and
Maiti, Subhabrata, Prins, Leonard J.
core +1 more source
Novel gene rearrangement pattern in mitochondrial genome of Ooencyrtus plautus Huang & Noyes, 1994: new gene order in Encyrtidae (Hymenoptera, Chalcidoidea) [PDF]
ZooKeys, 2022 Studies of mitochondrial genomes have a wide range of applications in phylogeny, population genetics, and evolutionary biology. In this study, we sequenced and analyzed the mitochondrial genome of Ooencyrtus plautus Huang & Noyes, 1994 ...
Zhi-Ping Xing +4 more
doaj +3 more sources
TRPV4 mRNA is elevated in the caudate nucleus with NPH but not in Alzheimer’s disease
Frontiers in Genetics, 2022 Symptoms of normal pressure hydrocephalus (NPH) and Alzheimer’s disease (AD) are somewhat similar, and it is common to misdiagnose these two conditions. Although there are fluid markers detectable in humans with NPH and AD, determining which biomarker is
Hunter White +8 more
doaj +1 more source
Folic Acid Effect on Arginase Activity in Human Colostrum and Mature Milk
Pteridines, 2012 Folic acid, or folates are available from a large variety of sources, such as green leafy vegetables (spinach, beans) and liver. The importance of folates is based on their requirement as coenzymes in the transfer and utilization of one-carbon units in a
Bjelakovic Ljiljana +7 more
doaj +1 more source
Scientific Reports, 2021 In response to UV irradiation, translesion DNA synthesis (TLS) utilizes specialized DNA polymerases to bypass replication-blocking lesions. In a well-established polymerase switch model, Polη is thought to be a preferred TLS polymerase to insert correct ...
Tonghui Bi +3 more
doaj +1 more source