Results 51 to 60 of about 46,331 (223)

Raman depolarization ratios in RNA and DNA are sensitive for sugar-base coupling [PDF]

open access: yes, 1995
Polarized and depolarized Raman spectra are obtained for a number of synthetic polynucleotides containing adenine, uracil, and thymine bases. The depolarization ratios are determined by two methods: (1) by dividing the -spectrum by the -spectrum and (2 ...
Benevides   +17 more
core   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Dependence of nucleotide physical properties on their placement in codons and determinative degree

open access: yes, 2007
Various physical properties such as dipole moment, heat of formation and energy of the most stable formation of nucleotides and bases were calculated by PM3 (modified neglect of diatomic overlap, parametric method number 3) and AM1 (Austin model 1 ...
Berezhnoy, A. Yu., Duplij, Steven
core   +1 more source

Biosynthetic potentials of metabolites and their hierarchical organization [PDF]

open access: yes, 2008
Peer reviewedPublisher ...
Ebenhoeh, Oliver   +2 more
core   +4 more sources

NMR and Solvent Effect Study on the Thymine-Adenine-Thymine Sequence: A Theoretical Investigation on chemical behavior of Nucleotides in solution

open access: yesEgyptian Journal of Biochemistry and Molecular Biology, 2008
In our current research, we have taken into account nuclear shielding parameters of Thymine-Adenine-Thymine (TAT) sequence using GIAO and Self-Consistent Reaction Field (SCRF) method at the level of HF/ 3-21G theory both in the gas phase and in different solvents such as water, ethanol, methanol, nitromethane and DMSO.
Monajjemi, M   +5 more
openaire   +2 more sources

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

open access: yesAdvanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung   +4 more
wiley   +1 more source

Genetic code on the dyadic plane

open access: yes, 2007
We introduce the simple parametrization for the space of codons (triples of nucleotides) by 8\times 8 table. This table (which we call the dyadic plane) possesses the natural 2-adic ultrametric.
A.Yu. Khrennikov   +16 more
core   +1 more source

Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions. [PDF]

open access: yes, 2014
Endogenous metabolism, environmental exposure, and treatment with some chemotherapeutic agents can all give rise to DNA alkylation, which can occur on the phosphate backbone as well as the ring nitrogen or exocyclic nitrogen and oxygen atoms of ...
Cai, Qian   +3 more
core   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

open access: yesAdvanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang   +12 more
wiley   +1 more source

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