Results 201 to 210 of about 67,295 (252)
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Thymocyte transformation enhanced
Nature Medicine, 2014A new study identifies recurrent somatic duplications of a NOTCH1-driven enhancer of MYC in human T cell leukemia. This enhancer is required for both normal and malignant T cell development.
Gayle P, Pouliot, Alejandro, Gutierrez
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Nature, 1963
FRAGRAEUS was not able to show plasmocytes in normal thymus1 ; nor did she find plasmocytes in thymus after antigen injections2. After removal of the thymus in adult rats the antibody production is unchanged3. In spite of these results which ascribe no important influence on antibody production by the thymus there are still several clinical signs which
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FRAGRAEUS was not able to show plasmocytes in normal thymus1 ; nor did she find plasmocytes in thymus after antigen injections2. After removal of the thymus in adult rats the antibody production is unchanged3. In spite of these results which ascribe no important influence on antibody production by the thymus there are still several clinical signs which
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Science, 2010
Cells that ensheath blood vessels promote exit of the developing T lymphocytes from the thymus.
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Cells that ensheath blood vessels promote exit of the developing T lymphocytes from the thymus.
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Positive Selection of Thymocytes
Annual Review of Immunology, 1995Differentiation of αβ T cell receptor (TCR)-expressing T cells involves an obligatory interaction with self-major histocompatibility complex (MHC) molecules in the thymus. This process, called positive selection, both rescues thymocytes from programmed cell death and induces their differentiation into mature T cells.
S C, Jameson, K A, Hogquist, M J, Bevan
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LDH analysis of human thymocytes and thymocyte subsets.
The Journal of Immunology, 1984Abstract The lactate dehydrogenase (LDH) isoenzyme pattern (expressed as the B:A subunit ratio) and two enzymes of the purine metabolism adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) (expressed as the ADA/PNP ratio) were studied in human prenatal thymocytes, in subsets of human infant thymocytes, and in peripheral T
J R, Plum +3 more
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Triiodothyronine Modulates Thymocyte Migration
Scandinavian Journal of Immunology, 2007AbstractTriiodothyronine (T3) exerts several effects on thymus physiology. In this sense, T3 is known to stimulate thymic microenvironmental cells to enhance the production of extracellular matrix (ECM) moieties, which are relevant in thymocyte migration.
M M, Ribeiro-Carvalho +5 more
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Thymocytes, macrophages, and erythrocytes
Journal of Allergy and Clinical Immunology, 1974Abstract Lymphocyte-macrophage and lymphocyte erythrocyte interactions were examined in the 4 homologous and 12 heterologous combinations of mice, rats, guinea pigs, and rabbits. There was a highly species-specific interaction between thymic lymphocytes (T cells) and homologous peritoneal macrophages.
L R, Lopez +3 more
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Specific Antigenicity of Thymocytes
Nature, 1967THYMOCYTES (thymic lymphocytes) are believed to differ from lymphoid cells of other organs. They show a different response to a variety of physical, chemical and biological stimuli1, such as irradiation2 and phytohaemagglutinin3, and it has been claimed that they have an epithelial rather than mesenchymal origin4.
Potworowski, E F, Nairn, R C
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Thymocyte progenitors in ageing
Immunology Letters, 1994The effect of ageing on thymocyte progenitors in the bone marrow was studied in an in vitro experimental model that permits T lymphocyte development. The model is based on co-culture of BM cells from young and old mice with lymphoid depleted fetal thymus explants.
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