Results 61 to 70 of about 316,970 (234)
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Intrapericardial Thymoma Presented as Pericardial Tamponade with Post-Operative Myasthenia Gravis
Medicina, 2022 Background: Thymoma is an epithelial mass arising from the thymus. Most thymomas are located in the anterior mediastinum. Ectopic intrapericardial thymoma is very unusual; to date, only eight cases of pericardial thymoma have been reported. Among thymoma
Yueh-Hsun Tsai +3 more
doaj +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source
Evaluation of anterior mediastinal solid tumors by CT perfusion: a preliminary study
Diagnostic and Interventional Radiology, 2017 PURPOSE:We aimed to assess the role of computed tomography (CT) perfusion in differentiation of thymoma from thymic hyperplasia, lymphoma, thymic carcinoma, and lung cancer invading anterior mediastinum.METHODS:In this study, 25 patients with an anterior
Selim Bakan +9 more
doaj +1 more source
Long-term disease-free survival of patients with radically resected thymomas: relevance of cell-cycle protein expression [PDF]
, 2005 BACKGROUND. Despite radical Surgical resection, thymomas often recur. The objective of the current retrospective Study was to investigate the prognostic relevance of the expression of cell-cycle proteins in these neoplasms to formulate a possible ...
Ambrogi, V, Baldi, A, Mineo, D, Mineo, T
core +1 more source
Advanced Science, EarlyView.An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou +30 more
wiley +1 more source
Tumor Encasement of the Right Coronary Artery: Role of Anatomic and Functional Imaging in Diagnosis and Therapeutic Management [PDF]
, 2014 We presented two rare cases of mediastinal tumor encasing the right coronary artery (RCA), one with recurrent metastatic thymoma and another with primary poorly differentiated neoplasm. Different degrees and locations of RCA involvement were noted.
Chatzizisis, Ioannis +5 more
core +1 more source
Advanced Science, EarlyView.Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma +12 more
wiley +1 more source
Cloning of terminal transferase cDNA by antibody screening [PDF]
, 1984 A cDNA library was prepared from a terminal deoxynucleotidyltransferase-containing thymoma in the phage vector λgt11. By screening plaques with anti-terminal transferase antibody, positive clones were identified of which some had β-galactosidase-cDNA ...
Baltimore, David +5 more
core
Development of a competing risk nomogram for the prediction of cause-specific mortality in patients with thymoma: a population- based analysis [PDF]
, 2021 Tao Zhang +5 more
openalex +1 more source