Results 61 to 70 of about 305,149 (190)

Identification of Potential Key Genes for the Comorbidity of Myasthenia Gravis With Thymoma by Integrated Bioinformatics Analysis and Machine Learning

Bioinformatics and Biology Insights
Background: Thymoma is a key risk factor for myasthenia gravis (MG). The purpose of our study was to investigate the potential key genes responsible for MG patients with thymoma.
Hui Liu, Geyu Liu, Rongjing Guo, Shuang Li, Ting Chang   +4 more
doaj   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

JEADV Clinical Practice, EarlyView.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri, Marta Dechant, Tilo Biedermann   +2 more
wiley   +1 more source

Whole‐Genome Bisulfite Sequencing Identifies Blood‐Based DNA Methylation Biomarker for Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Functional DNA methylation abnormalities are a hallmark of human cancers and may be a promising biomarker for their early diagnosis. Moreover, the largest methylation differences can improve the sensitivity of noninvasive diagnoses of solid tumors.
Junsheng Zhao, Sijia Shen, Junjie Zhang, Ying Xu, Jing Peng, Hainv Gao, Lanjuan Li   +6 more
wiley   +1 more source

Experience Using Efgartigimod to Treat Juvenile Myasthenia Gravis in China: A Multicenter Retrospective Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Current therapeutic management of juvenile myasthenia gravis (JMG) predominantly relies on conventional immunosuppressive therapies and expert consensus extrapolated from adult data, creating a critical gap in high‐quality, pediatric‐specific clinical evidence.
Jing Lin, Guoyan Qi, Susan Luo, Qilong Jiang, Bitao Bu, Min Liu, Yuzhen Wei, Meigui Han, Junhong Yang, Zhilan Zhao, Lili Zhang, Yifan Zhang, Haoyou Xu, Xingjie Hao, Zhijun Li   +14 more
wiley   +1 more source

Increased Prevalence of Extrathymic Neoplasms in Myasthenia Gravis Patients‐A Population‐Based, Matched Case–Control Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Myasthenia gravis (MG) is associated with thymic neoplasms. However, an increased prevalence of extrathymic neoplasms has also been reported. This study aimed to evaluate the rates of malignancy in MG patients while accounting for risk factors such as disease characteristics and immunomodulatory treatments.
Keshet Pardo, Tasneem Kab, Mark A. Hellmann, Itay Lotan, Tzippy Shochat, Nadav Loebl, Bar Yacobi, Yitzhak Friedman, Leor Perl, Nitai Shimon, Yiska Loewenberg Weisband, Liya Bieber, Eitan Auriel, Adi Wilf‐Yarkoni   +13 more
wiley   +1 more source

The Effect of Thymectomy on the Incidence of Extrathymic Cancers and Autoimmune Diseases in Patients With Non‐Thymomatous Myasthenia Gravis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Thymectomy is associated with positive effects on myasthenia gravis (MG), but there is conflicting evidence regarding potential deleterious long‐term outcomes, such as increased cancer and autoimmune disease risk. We aimed to assess these outcomes in thymectomized versus non‐thymectomized MG patients.
Mohamed Khateb, Adnan Almasri, Carolina Barnett‐Tapia, Vera Bril   +3 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Evaluation of safety and efficacy of an ophytrium and seboliance‐containing mousse with or without shampoo in cats with keratinisation disorders

Journal of Small Animal Practice, EarlyView.
Objectives This study aimed to assess the effectiveness of a protocol involving the application of topical products (DOUXO® S3 SEB Shampoo and Mousse; Ceva Santé Animale) containing ophytrium for managing feline keratinisation disorders. Materials and Methods Nineteen client‐owned cats with a history of keratinisation disorders exhibited greasy or dry ...
C. Noli, H. Dropsy, A. Cozar, X. De Jaeger, R. Kesteman, A. Beck, R. Cristante, M. Debraine, F. Leymarios, A. Puozzo‐Barichard, M. Gatellet   +10 more
wiley   +1 more source

Association Between Oral Lichen Planus and Non‐Oral Cancers: A Multicentre Case–Control SIPMO Study

Oral Diseases, EarlyView.
ABSTRACT Objectives This multicentre case–control study aimed to investigate the potential association between oral lichen planus (OLP) and extraoral cancers. The secondary objective included the identification of risk factors for this association. Methods The study was conducted between January 2023 and June 2024 and included 21 Italian Oral Medicine ...
Gioele Gioco, Anna Schiavelli, Alessandra Majorana, Elena Bardellini, Silvio Abati, Andrea Sardella, Francesco Spadari, Matteo Pellegrini, Dorina Lauritano, Raffaele Borgia, Monica Pentenero, Samuele Sutera, Paolo Giacomo Arduino, Alessio Gambino, Roberto Broccoletti, Matteo Biasotto, Giulia Ottaviani, Lorenzo Azzi, Alessandro D'Aiuto, Davide Bartolomeo Gissi, Andrea Gabusi, Andrea Santarelli, Marco Mascitti, Paolo Vescovi, Gloria Bortolotti, Maddalena Manfredi, Marco Meleti, Grazia Zino, Umberto Romeo, Gianluca Tenore, Gianfranco Favia, Luisa Limongelli, Massimo Petruzzi, Francesca Dimilito, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Giuseppina Campisi, Vera Panzarella, Stefania Leuci, Rosario Serpico, Alberta Lucchese, Giuseppe Colella, Giacomo Oteri, Antonia Marcianò, Gaetano Isola, Alessandro Polizzi, Amerigo Giudice, Elena Calabria, Umberto Mariani, Daniela Adamo, Federica Canfora, Filippo Graziani, Marco Nisi, Michele Giuliani, Luisa Ritrovato, Federica De Micheli, Cosimo Rupe, Francesco Scilla, Romeo Patini, Massimo Cordaro, Michele Davide Mignogna, Carlo Lajolo, SIPMO (Italian Society of Oral Pathology and Medicine)   +62 more
wiley   +1 more source

Cystic cervical thymoma in a cat

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 12‐year‐old, female, neutered Persian cat was presented with a 4‐month history of a progressively enlarging, soft, fluctuating, ventral cervical mass that intermittently caused dysphagia and coughing. Repeated aspiration temporarily reduced the swelling.
Rachel L. Nixon, Andreu Masdefiol Garriga, Sophie Griffin, Dario Costanza, Kathryn M. Pratschke   +4 more
wiley   +1 more source