Results 61 to 70 of about 327,270 (275)

Long-term disease-free survival of patients with radically resected thymomas: relevance of cell-cycle protein expression [PDF]

, 2005
BACKGROUND. Despite radical Surgical resection, thymomas often recur. The objective of the current retrospective Study was to investigate the prognostic relevance of the expression of cell-cycle proteins in these neoplasms to formulate a possible ...
Ambrogi, V, Baldi, A, Mineo, D, Mineo, T
core   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Imaging Thymoma [PDF]

Journal of Thoracic Oncology, 2010
Thymoma is a rare tumor, although it is the most common primary neoplasm of the anterior mediastinum. In the majority of thymoma patients, imaging is requested for investigation of symptoms related to their tumor, although an increasing number of asymptomatic patients are discovered incidentally due to the increased utilization of computed tomography ...
openaire   +2 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

The role of regulatory B cell/T follicular helper cell balance in thymoma and thymoma-associated myasthenia gravis

Scientific Reports
Thymoma is often associated with myasthenia gravis (MG). Abnormal lymphocyte differentiation often occurs in the thymoma tumor microenvironment (TME), leading to thymoma-associated autoimmune diseases.
Peng Zhang, Yuxin Liu, ZiYou Tao, Xinyu Zhang, Yuanguo Wang, Hui Zhang, Jian Li, Zhaoyu Yang, Kai Xiong, Shuning Duan, Zeyang Zhang, Yan Wang, Huan Wang   +12 more
doaj   +1 more source

Genome-wide genetic aberrations of thymoma using cDNA microarray based comparative genomic hybridization

BMC Genomics, 2007
Background Thymoma is a heterogeneous group of tumors in biology and clinical behavior. Even though thymoma is divided into five subgroups following the World Health Organization classification, the nature of the disease is mixed within the subgroups ...
Park Chan, Seo Min, Kim Sang, Jeung Hei, Yang Woo, Lee Gui, Chung Hyun, Rha Sun   +7 more
doaj   +1 more source

Cloning of terminal transferase cDNA by antibody screening [PDF]

, 1984
A cDNA library was prepared from a terminal deoxynucleotidyltransferase-containing thymoma in the phage vector λgt11. By screening plaques with anti-terminal transferase antibody, positive clones were identified of which some had β-galactosidase-cDNA ...
Baltimore, David, Landau, Nathaniel R., Silverstone, Allen E., St. John, Thomas P., Weissman, Irving L., Wolf, Susan C.   +5 more
core  

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

An unusual location of micronodular thymoma with lymphoid stroma: A posterior mediastinal mass invading into pleura

Human Pathology Reports, 2023
Micronodular thymoma with lymphoid stroma (MNTL) is a rare type of thymoma that is often found alongside Type A thymoma. Here, we present a case of MNTL diagnosed in an 82 year-old-female who had a thymus excision seven years prior.
Utku Ekin, Ahmad M. Alkhatatneh, Lan Wang, Mourad Ismail   +3 more
doaj   +1 more source

EZH2 and POU2F3 Can Aid in the Distinction of Thymic Carcinoma from Thymoma [PDF]

, 2023
Julia Naso, Julie A. Vrana, Justin W. Koepplin, Julian R. Molina, Anja C. Roden   +4 more
openalex   +1 more source