Results 81 to 90 of about 9,080 (213)

Skeletal Muscle Relaxant Effects of Thymoquinone, the Major Constituent of Nigella sativa

Journal of Medicinal Plants, 2015
Background: It has been shown that Nigella sativa seeds has several pharmacological activities such as sedative effects, decrease in locomotor activity and muscle relaxation.
S Parvardeh, M Moghimi
doaj  

ANTIHYPERGLYCEMIC EFFECTS OF THYMOQUINONE IN DIABETIC RATS

Basrah Journal of Veterinary Research, 2014
To investigate the antihyperglycemic potent of thymoquinone (TQ), this study has been conducted in streptozotocin-induced diabetic male rats.Diabetes was induced by single injection with streptozotocin (60 mg/kg b.w., i.p.). Rat ≥ 200 mg/dl of blood glucose was used as diabetic.Sixty five adult male rats (aged 56 days and weighted 138±8.8g) were ...
Jabbar A.A. Al-Sa, Hashim M.A. Kareem, aidi, Wijdan T.M. Al-Tameemi   +3 more
openaire   +2 more sources

Acrylamide‐Induced Developmental and Molecular Toxicity in Drosophila melanogaster: The Role of Vanillic Acid in CncC/Keap1 Modulation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Vanillic acid, a dietary phenolic, dose‐dependently protects Drosophila melanogaster from acrylamide‐induced oxidative damage, DNA strand breaks, and developmental toxicity by modulating CncC/Keap1 redox signaling—establishing vanillic acid as a candidate natural protective agent against a major environmental contaminant.
Fahriye Zemheri‐Navruz, Sinan Ince, Gamze Ataman   +2 more
wiley   +1 more source

Effects of Low Doses of Exogenous Thymoquinone on Sperm Motility and Viability of Normozoospermic Men

مجله دانشکده پزشکی اصفهان, 2014
Background: Sperm motility is a highly complex molecular process which is the result of transverse waves exist along its flagellum. Thymoquinone (TQ) is the most abundant active component isolated from black seed (Nigella Sativa). It was revealed that in-
Khatereh Fazelian, Gholamreza Dashti, Farhad Golshan Iranpour, Shekofeh Baghazadeh   +3 more
doaj  

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

The Combination of 3-Hydrazinoquinoxaline-2-Thiol with Thymoquinone Demonstrates Synergistic Activity Against Different Candida Strains [PDF]

Mohammed A Bazuhair,1,2 Mohammed Alsieni,1 Hani Abdullah,3 Jawahir A Mokhtar,3– 5 Dalya Attallah,4 Turki S Abujamel,5,6 Khalil K Alkuwaity,5,6 Hanouf A Niyazi,3 Hatoon A Niyazi,3 Hind AbdulMajed,3 Noha Juma,3 Mohammed W Al-Rabia,3 Abdelbagi Alfadil,2,3 ...
Al-Rabia MW, Bazuhair MA, Juma N, AbdulMajed H, Alkuwaity KK, Abdullah H, Alfadil A, Niyazi HA, Alsieni M, Mokhtar JA, Abujamel TS, Attallah D, Ibrahem K   +12 more
core  

Apoptotic effect of thymoquinone on OVCAR3 cells via the P53 and CASP3 activation [PDF]

Acta Cirúrgica Brasileira
Purpose: The limitations in cancer treatment and the inadequacy of classical methods have made it necessary to discover therapeutics in cancer treatment.
Özge Karaosmanoğlu, Zeynep Kamalak, İlhan Özdemir, Şamil Öztürk, Mehmet Cudi Tuncer   +4 more
doaj   +1 more source

Dual‐Drug‐Loaded Liposomes: Design Strategies, Mechanistic Insights, and Therapeutic Applications in Cancer

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Dual‐drug‐loaded liposomes enable the simultaneous delivery of hydrophilic and hydrophobic therapeutics to tumors, enhancing anticancer efficacy and overcoming multidrug resistance. Through rational formulation design and surface functionalization, these systems improve tumor targeting, modulate efflux mechanisms and EMT, and achieve synergistic ...
Neelam Sinha, Rohan Chand Sahu, Rohit Patil, Dinesh Kumar, Ashish Kumar Agrawal   +4 more
wiley   +1 more source

A Raman Spectroscopic Study of Thymoquinone Antitumor Action

, 2020
Fluorescence assay and Raman spectroscopy were used to study the mechanisms of action of 2-isopropyl-5-methyl-1,4-benzoquinone (thymoquinone) on HEp-2 human larynx carcinoma cells.
Martinovich, G. G., Vcherashniaya, A. V., Shadyro, O. I., Martinovich, I. V., Cherenkevich, S. N.   +4 more
core   +1 more source

The use of thymoquinone in nephrotoxicity related to acetaminophen

International Journal of Surgery, 2015
We aimed to investigate efficacy of intraperitoneally administered Thymoquinone (TQ) in acetaminophen (APAP) induced renal toxicity.Forty Wistar Albino rats were randomly divided into 4 groups of ten rats each. Control group was untreated group while rats in TQ group were treated with single dose TQ.
Aycan, İlker Öngüç, Tokgöz, Orhan, Tüfek, Adnan, Alabalık, Ulaş, Evliyaoğlu, Osman, Turgut, Hüseyin, Çelik, Feyzi, Güzel, Abdulmenap   +7 more
openaire   +2 more sources