Results 81 to 90 of about 13,156 (231)

Effect of Thymoquinone on Reproductive Parameter in Morphine-treated Male Mice

Advanced Biomedical Research, 2018
Background: Thymoquinone as the main active component of Nigella sativa might have a various pharmacological effects such as antiapoptotic and antioxidant.
Mohammad Reza Salahshoor, Mojdeh Haghjoo, Shiva Roshankhah, Fatemeh Makalani, Cyrus Jalili   +4 more
doaj   +1 more source

Extraction, Gene Regulation and Hypocholesterolemic Effects, and Antioxidative Activity of Thymoquinone Rich Fraction and Thymoquinone from Nigella Sativa (pdf incomplete) [PDF]

, 2009
Nigella sativa and its active constituent thymoquinone (TQ) have been used for various health benefits such as antitumor, antidiabetic, antihypertensive, antioxidatative and antibacterial.
Al-Naqeeb, Ghanya Naji
core  

Impact of Soybean Meal, Mustard Meal, Rapeseed Meal and Black Cumin on Production Performance, Egg Quality and Gut Microflora of Laying Hens

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The inclusion of novel protein sources such as mustard meal, rapeseed meal and black cumin in layer diets demonstrates promising results without compromising egg quality, improves body weight gain and reduced gut microflora and Escherichia coli. Overall, strategically integrating these alternative protein sources shows potential for cost savings ...
Md Abubakar Siddik, Mst Afroza Khatun, Sweety Rani Mondal, Shoriful Islam, Md. Azizul Haque, Khadiza Akter Brishty, Hemayet Hossain, Md. Mahfujur Rahman   +7 more
wiley   +1 more source

Skeletal Muscle Relaxant Effects of Thymoquinone, the Major Constituent of Nigella sativa

Journal of Medicinal Plants, 2015
Background: It has been shown that Nigella sativa seeds has several pharmacological activities such as sedative effects, decrease in locomotor activity and muscle relaxation.
S Parvardeh, M Moghimi
doaj  

Attenuation of morphine tolerance and dependence by thymoquinone in mice [PDF]

Avicenna Journal of Phytomedicine, 2016
Objectives: Dependence and tolerance are major restricting factors in the clinical use of opioid analgesics. In the present study, the effects of thymoquinone, the major constituent of Nigella sativa seeds, on morphine dependence and tolerance were ...
Hossein Hosseinzadeh, Siavash Parvardeh, Alireza Masoudi, Mahsa Moghimi, Fatemeh Mahboobifard   +4 more
doaj  

Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro.

PLoS ONE, 2014
BackgroundThymoquinone is an active ingredient isolated from Nigella sativa (Black Seed). This study aimed to evaluate the in vitro and in vivo anti-leukemic effects of thymoquinone on WEHI-3 cells.Methodology/principal findingsThe cytotoxic effect of ...
Landa Zeenelabdin Ali Salim, Rozana Othman, Mahmood Ameen Abdulla, Karim Al-Jashamy, Hapipah Mohd Ali, Pouya Hassandarvish, Firouzeh Dehghan, Mohamed Yousif Ibrahim, Fatima Abd Elmutaal Ahmed Omer, Syam Mohan   +9 more
doaj   +1 more source

Antiproliferative and Apoptosis-Inducing Activities of Thymoquinone in Lymphoblastic Leukemia Cell Line [PDF]

, 2016
Acute lymphoblastic leukemia is one of the malignant proliferations of lymphoid cells in the early stages of differentiation and accounts for about 80% of all cases of childhood leukemia.
Pourgheysari, Batoul., shirzad, Hedayatollah., Soltani, Amin., Sourani, Zahra.   +3 more
core   +1 more source

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

eFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

Apoptotic effect of thymoquinone on OVCAR3 cells via the P53 and CASP3 activation [PDF]

Acta Cirúrgica Brasileira
Purpose: The limitations in cancer treatment and the inadequacy of classical methods have made it necessary to discover therapeutics in cancer treatment.
Özge Karaosmanoğlu, Zeynep Kamalak, İlhan Özdemir, Şamil Öztürk, Mehmet Cudi Tuncer   +4 more
doaj   +1 more source

Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal, Muhammad Shahbaz, Asfa Perween, Muhammad Hammad ul Hassan, Hammad Naeem, Zubda Shahid, Muzzamal Hussain, Muhammad Imran, Suliman A. Alsagaby, Waleed Al Abdulmonem, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Tadesse FentaYehuala, Samy Selim, Ehab M. Mostafa   +14 more
wiley   +1 more source