Inhaled pretreatment of mouse lungs with immunomodulatory Pam2ODN results in lung epithelial cell epigenetic reprogramming that is associated with attenuation of house dust mite extract (HDM)‐induced cDC2s and moDCs expansion in the lung, causing tolerance against HDM sensitization and restricting Th2‐cell‐induced airway eosinophilic allergic ...
Mbaya Ntita +7 more
wiley +1 more source
Background: Thymoquinone, the major constituent of Nigella sativa seeds, is a biologically active compound, which possesses several pharmacological effects. Objective: The aim of the present study was to evaluate the anticonvulsant effect of thymoquinone
S Parvardeh +3 more
doaj
The Evaluation of the effects of cytotoxic, anti-proliferative and anti-migrative effects of the thymoquinone on PC3 prostate cancer cell line [PDF]
Background & Objective: Herbal medicine and their composition are widely used for different therapeutic purposes. Therefore, this study was designed to evaluate of the anti-proliferation and anti-migration effects of Thymoquinone (TQ), an active part of ...
iraj Khodadadi, gholamreza Shafiee
doaj
Thymoquinone Loaded Topical Nanoemulgel for Wound Healing: Formulation Design and In-Vivo Evaluation
Thymoquinone is a natural bioactive with significant therapeutic activity against multiple ailments including wound healing. The poor aqueous solubility and low skin permeability limit its therapeutic efficacy.
Mohammed S. Algahtani +5 more
doaj +1 more source
Katalitička oksidacija i antioksidacijska svojstva eteričnih ulja timijana (Thymus vulgaris L.) [PDF]
The antioxidant properties of two chemotypes of thyme essential oils were examined in relation to their catalytic transformation. Catalytic oxidations were performed with potassium hydrogentrioxoperoxosulfate(VI) and the FeIII meso-tetraphenylporphyrin ...
Mila Jukić, Mladen Miloš
core +1 more source
Maternal supplementation of diabetic mice with thymoquinone protects their offspring from abnormal obesity and diabetes by modulating their lipid profile and free radical production and restoring lymphocyte proliferation via PI3K/AKT signaling [PDF]
BACKGROUND: Epidemiological studies have shown that the offspring of mothers who experience diabetes mellitus during pregnancy are seven times more likely to develop health complications than the offspring of mothers who do not suffer from diabetes ...
Danny M Rabah +5 more
core +1 more source
Thymus serpyllum (wild thyme) contains bioactive compounds such as carvacrol, thymol, β‐caryophyllene, γ‐terpinene, and α‐thujene, along with essential vitamins and minerals. These constituents exhibit antioxidant, antimicrobial, anti‐inflammatory, and antidiabetic activities.
Ahmad Mujtaba Noman +8 more
wiley +1 more source
Effects of thymoquinone supplementation on somatostatin secretion in pancreas tissue of rats [PDF]
In this study, it was aimed to investigate the effects of thymoquinone (TQ), which is the bioactive phytochemical constituent of the seeds oil of Nigella sativa, on somatostatin secretion in the rat pancreatic tissue by immunohistochemical method ...
BAKIR B +3 more
doaj +1 more source
Effect of Thymoquinone on Mouse Dendritic Cells [PDF]
Thymoquinone, a component of Nigella sativa is known to confer protection against tumour growth due to stimulation of tumour cell apoptosis. Moreover, thymoquinone has remarkable anti-inflammatory potency. Surprisingly, despite its powerful influence on inflammation and its immunomodulatory effects, little is known about its effect on dendritic cells ...
Nguyen Thi, Xuan +4 more
openaire +2 more sources
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali +4 more
wiley +1 more source

