Results 41 to 50 of about 13,156 (231)

Development of Stable Liposomal Drug Delivery System of Thymoquinone and Its In Vitro Anticancer Studies Using Breast Cancer and Cervical Cancer Cell Lines

Molecules, 2022
Thymoquinone, a well-known phytoconstituent derived from the seeds of Nigella sativa, exhibits unique pharmacological activities However, despite the various medicinal properties of thymoquinone, its administration in vivo remains challenging due to poor
Mohammad Hossain Shariare, Md Asaduzzaman Khan, Abdullah Al-Masum, Junayet Hossain Khan, Jamal Uddin, Mohsin Kazi   +5 more
doaj   +1 more source

Thymoquinone is a natural antibiofilm and pathogenicity attenuating agent in Pseudomonas aeruginosa

Frontiers in Cellular and Infection Microbiology
Pseudomonas aeruginosa belongs to the critical pathogens that represent a global public health problem due to their high rate of resistance as listed by WHO. P.
Mohammed W. Al-Rabia, Hani Z. Asfour, Nabil A. Alhakamy, Nabil A. Alhakamy, Nabil A. Alhakamy, Wesam H. Abdulaal, Tarek S. Ibrahim, Hisham A. Abbas, Ibrahim M. Salem, Wael A. H. Hegazy, Wael A. H. Hegazy, Shaimaa I. Nazeih   +11 more
doaj   +1 more source

Therapeutic Effects of Thymoquinone in a Model of Neuropathic Pain

Current Therapeutic Research, 2014
Background: The goal of our study was to determine the therapeutic effects of thymoquinone in a dose-dependent manner in a model of neuropathic pain following an experimentally applied spinal cord injury (SCI).
Feyzi Çelik, MD, Cüneyt Göçmez, MD, Haktan Karaman, MD, Kağan Kamaşak, MD, İbrahim Kaplan, MD, Eşref Akıl, MD, Adnan Tufek, MD, Abdulmenap Guzel, MD, Ertuğrul Uzar, MD   +8 more
doaj   +1 more source

PENGARUH PEMBERIAN TERAPI MINYAK Nigella sativa DAN KOMBINASINYA DENGAN SEFTRIAKSON TERHADAP JUMLAH KUMAN Methicillin Resistant Staphylococcus aureus (MRSA) PADA KULTUR LIMPA MENCIT BALB/c [PDF]

, 2015
Background Methicillin Resistant Staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus which is resistant to metichilin and another antibiotics. Researchs are being developed to find new therapies for MRSA infection.
Dharmana, Edi, Hadi, Purnomo, VALENCIA, LOVENIA   +2 more
core   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Phytochemistry, pharmacology, and therapeutic uses of black seed (Nigella sativa) [PDF]

, 2016
Black seed (Nigella sativa) is an annual flowering plant from Ranunculaceae family, native to southwest Asia. This plant has many food and medicinal uses.
Asadi-Samani, Majid., Ashtary-Larky, Damoon., Hasanzadeh Noohi, Zahra., Kooti, Wesam., Sharafi-Ahvazi, Naim.   +4 more
core   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Chemical composition of Nigella sativa Linn : Part 2 Recent advances [PDF]

, 2016
The black cumin or Nigella sativa L. seeds have many acclaimed medicinal properties such as bronchodilatory, hypotensive, antibacterial, antifungal, analgesic, anti-inflammatory and immunopotentiating.
Afzal, M, Khan, Akram
core   +1 more source

Influence of nanohydroxyapatite mouthwash on the growth of Candida albicans biofilm on milled denture surfaces: An in vitro study

Journal of Prosthodontics, EarlyView.
Abstract Purpose There is a need for effective solutions for the persistent prevalence of denture stomatitis (DS) in denture‐wearing populations. This study assessed the impact of nanohydroxyapatite (nanoHAP) nanoparticles on Candida albicans biofilm formation on milled polymethylmethacrylate (PMMA) denture bases.
Cynthia U. Udeh, Bennett T. Amaechi, Parveez A. Abdul‐Azees, Amos C. Obiefuna, Chun‐Yen Lin, Nahid IftiKhar, Sunil Mankar, Temitope O. Omosebi, Tejal Gohil   +8 more
wiley   +1 more source

Black Cumin Seed Oilas Hepatoprotector in Decreasing SGPT and SGOT Activity and Increasing P53 Gene Expression in Sprague Dawley Rats Induced by Alloxan [PDF]

, 2015
The objective of this research was to determine the effect of BCSO on SGPT/SGOT levels and p53 expression in rats induced by alloxan. This study applied a post test only control group design. A total of 42 SD rats were divided into 6 groups.
Akrom, A. (Akrom), Darmawan, E. (Endang), Yuhelvia, L. (Liesma)   +2 more
core