Results 51 to 60 of about 9,080 (213)

The Evaluation of the effects of cytotoxic, anti-proliferative and anti-migrative effects of the thymoquinone on PC3 prostate cancer cell line [PDF]

Journal of Advanced Biomedical Sciences, 2019
Background & Objective: Herbal medicine and their composition are widely used for different therapeutic purposes. Therefore, this study was designed to evaluate of the anti-proliferation and anti-migration effects of Thymoquinone (TQ), an active part of ...
iraj Khodadadi, gholamreza Shafiee
doaj  

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Neohesperidin Alleviates Ferroptosis in Doxorubicin‐Induced Cardiotoxicity via Mettl3‐m6A‐Nrf2 Signaling

Phytotherapy Research, EarlyView.
Neohesperidin alleviates doxorubicin‐induced cardiotoxicity by inhibiting METTL3‐mediated m6A modification of Nrf2 mRNA, thereby regulating Nrf2 and suppressing ferroptosis. ABSTRACT Doxorubicin (DOX) has antitumor efficacy, but its clinical application is restricted by multiple side effects, especially cardiotoxicity.
Ruijia Wen, Xin Dong, Haowen Zhuang, Yusheng Huang, Mengyuan Wang, Zhongzheng Zhang, Jinhong Chen, Wei Wang, Chun Li, Junyan Wang   +9 more
wiley   +1 more source

Effects of thymoquinone in prevention of experimental contrast-induced nephropathy in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): This study aimed to show the effects of thymoquinone, which is known for its antioxidant, anti-inflammatory, and renal protective effects in contrast-induced nephropathy.Materials and Methods: This is an experimental study in rats. 7 groups
Ulaş Serkan Topaloğlu, Murat Hayri Sipahioğlu, İnayet Güntürk, Hülya Akgün, Muhammet Ensar Doğan, Gökhan Sönmez, Ferhan Elmalı, Cevat Yazıcı   +7 more
doaj   +1 more source

Thymoquinone Loaded Topical Nanoemulgel for Wound Healing: Formulation Design and In-Vivo Evaluation

Molecules, 2021
Thymoquinone is a natural bioactive with significant therapeutic activity against multiple ailments including wound healing. The poor aqueous solubility and low skin permeability limit its therapeutic efficacy.
Mohammed S. Algahtani, Mohammad Zaki Ahmad, Ibrahim Ahmed Shaikh, Basel A. Abdel-Wahab, Ihab Hamed Nourein, Javed Ahmad   +5 more
doaj   +1 more source

Effect of Thymoquinone on Mouse Dendritic Cells [PDF]

Cellular Physiology and Biochemistry, 2010
Thymoquinone, a component of Nigella sativa is known to confer protection against tumour growth due to stimulation of tumour cell apoptosis. Moreover, thymoquinone has remarkable anti-inflammatory potency. Surprisingly, despite its powerful influence on inflammation and its immunomodulatory effects, little is known about its effect on dendritic cells ...
Nguyen Thi, Xuan, Ekaterina, Shumilina, Syed M, Qadri, Friedrich, Götz, Florian, Lang   +4 more
openaire   +2 more sources

Influence of nanohydroxyapatite mouthwash on the growth of Candida albicans biofilm on milled denture surfaces: An in vitro study

Journal of Prosthodontics, EarlyView.
Abstract Purpose There is a need for effective solutions for the persistent prevalence of denture stomatitis (DS) in denture‐wearing populations. This study assessed the impact of nanohydroxyapatite (nanoHAP) nanoparticles on Candida albicans biofilm formation on milled polymethylmethacrylate (PMMA) denture bases.
Cynthia U. Udeh, Bennett T. Amaechi, Parveez A. Abdul‐Azees, Amos C. Obiefuna, Chun‐Yen Lin, Nahid IftiKhar, Sunil Mankar, Temitope O. Omosebi, Tejal Gohil   +8 more
wiley   +1 more source

Protective effects of thymoquinone against methotrexate-induced testicular injury

, 2010
Thymoquinone is the major active component derived from Nigella sativa. Methotrexate is a folic acid antagonist widely used in clinic. Aim of this study was to investigate the possible protective role of thymoquinone on testicular toxicity of ...
Ahmet Gokce, Zafer Yonden, Suleyman Oktar, Oktar, Suleyman, Gökçe, Ahmet, Koc, Ahmet, Ahmet Koc, Yonden, Zafer   +7 more
core   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

Study on the anticonvulsant activity of thymoquinone, the major constituent of Nigella sativa L. seeds, through intracerebroventricular injection

Journal of Medicinal Plants, 2005
Background: Thymoquinone, the major constituent of Nigella sativa seeds, is a biologically active compound, which possesses several pharmacological effects. Objective: The aim of the present study was to evaluate the anticonvulsant effect of thymoquinone
S Parvardeh, M Nassiri-Asl, MT Mansouri, H Hosseinzadeh   +3 more
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