Results 31 to 40 of about 13,156 (231)

Role of L-arginine/NO/cGMP/KATP channel signaling pathway in the central and peripheral antinociceptive effect of thymoquinone in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
Objective(s): Growing evidence demonstrates that L-arginine/NO/cGMP/KATP channel pathway has a modulatory role in pain perception. Previous studies have shown that thymoquinone exerts antinociceptive effects; however, the mechanisms underlying ...
Siavash Parvardeh   +5 more
doaj   +1 more source

Unlocking the potential of PLGA/thymoquinone nanoparticles: a promising frontier in asthma therapeutics [PDF]

open access: yesNanomedicine Journal
Objective(s): To formulate mPEG-PLGA/Thymoquinone nanoparticles for enhanced biological uptake and therapeutic effectiveness of thymoquinone in asthmatic mice induced with ovalbumin (OVA) administration.Materials and Methods: mPEG-PLGA/thymoquinone ...
Mohsen Rahmanian   +4 more
doaj   +1 more source

Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats

open access: yesSaudi Pharmaceutical Journal, 2020
Thymoquinone is the most biologically active constituent of Nigella sativa (black seed). A monoterpene compound chemically known as 2-methyl-5-isopropyl-1, 4-quinone.
Ajaz Ahmad   +5 more
doaj   +1 more source

Antibacterial and resistance-modifying activities of thymoquinone against oral pathogens [PDF]

open access: yes, 2011
Background The presence of resistant bacteria in the oral cavity can be the major cause of dental antibiotic prophylaxis failure. Multidrug efflux has been described for many organisms, including bacteria and fungi as part of their drugs resistance ...
Bochra Kouidhi   +6 more
core   +2 more sources

The effects of thymoquinone against morphine-induced damages on male mice liver

open access: yesInternational Journal of Preventive Medicine, 2018
Background: Morphine is a pain medication .It is mostly processed in liver and reasons disturbing effects. It can increase the production of free radicals. Thymoquinone is a phytochemical compound found in the plant Nigella sativa.
Mohammad Reza Salahshoor   +4 more
doaj   +1 more source

Oxidation of monoterpenes catalysed by a water-soluble Mn(III) PEG-porphyrin in a biphasic medium [PDF]

open access: yes, 2018
It is well established that the transformation of abundant and cheap natural products, such as terpenoids, can produce other more valuable compounds.
Dehaen, Wim   +6 more
core   +2 more sources

Biological Potential of the Main Component, Thymoquinone, of Nigella sativa in Pulp Therapy—In Vitro Study

open access: yesLife, 2022
This work is designed to assess the antimicrobial efficacy, chelating efficacy, and dissolving capability of the bioactive agent of the Nigella sativa plant (thymoquinone). Four freeze-dried microorganisms were studied.
Rana A. Alamoudi   +2 more
doaj   +1 more source

Intestinal, Airway, and Cardiovascular Relaxant Activities of Thymoquinone [PDF]

open access: yes, 2012
Thymoquinone (TQ) is a bioactive component found in many medicinal herbs. In this study, we report the smooth and cardiac muscle relaxant activities of this compound.
Ghayur, Muhammad Nabeel   +2 more
core   +3 more sources

In vitro AND in silico EVALUATION OF THYMOQUINONE AS POTENTIAL ANTICANCER AGENT IN HUMAN ACUTE MYELOID LEUKEMIA HL-60 CELLS

open access: yesTrakya University Journal of Natural Sciences, 2022
This study aims to explore the cytotoxic, apoptotic and autophagic effects of thymoquinone on human acute myeloid leukemia. The cytotoxic effects of thymoquinone were determined with 3-(4, 5-dimethylthiazol-2-yl)-2 and 5-diphenyltetrazolium bromide (MTT)
Neslihan Tekin Karacaer
doaj   +1 more source

Antidotal effects of thymoquinone against neurotoxic agents [PDF]

open access: yesInterdisciplinary Toxicology, 2018
Abstract Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this
Sanati, Ali Rajabpour   +2 more
openaire   +2 more sources

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