Results 31 to 40 of about 9,080 (213)
Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Rhabdomyolysis leads to the release of myoglobin, sarcoplasmic proteins, and electrolytes into the blood circulation causing acute kidney injury (AKI). Thymoquinone, a natural compound found in Nigella sativa seeds, has antioxidant and anti-
Arezoo Hosseini +7 more
doaj +1 more source
Protective effect of thymoquinone, the active constituent of Nigella sativa fixed oil, against ethanol toxicity in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Long term consumption of ethanol may induce damage to many organs. Ethanol induces its noxious effects through reactive oxygen species production, and lipid peroxidation and apoptosis induction in different tissues and cell types.
Sayed Masoud Hosseini +5 more
doaj +1 more source
Synthesis and Characterization of Iron oxide Nanoparticles with Thymoquinone [PDF]
, 2023 Nigella sativa is a medicinal plant used for its antimicrobial properties. Thymoquinone (TQ) being the lead component of this plant seeds, exerts antibacterial, antifungal and antioxidant activity.
Tarun, M +3 more
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Effects of Topical Thymoquinone in an Experimental Dry Eye Model [PDF]
, 2018 Objectives:To comparatively evaluate the effects of thymoquinone (TQ), the biologically active main component of volatile oil derived from Nigella sativa seeds, in an experimental dry eye model.Materials and Methods:A total of 36 BALB/c mice 10 weeks of ...
Tolga Kocatürk +17 more
core +1 more source
Saudi Pharmaceutical Journal, 2020 Thymoquinone is the most biologically active constituent of Nigella sativa (black seed). A monoterpene compound chemically known as 2-methyl-5-isopropyl-1, 4-quinone.
Ajaz Ahmad +5 more
doaj +1 more source
Role of L-arginine/NO/cGMP/KATP channel signaling pathway in the central and peripheral antinociceptive effect of thymoquinone in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Growing evidence demonstrates that L-arginine/NO/cGMP/KATP channel pathway has a modulatory role in pain perception. Previous studies have shown that thymoquinone exerts antinociceptive effects; however, the mechanisms underlying ...
Siavash Parvardeh +5 more
doaj +1 more source
Unlocking the potential of PLGA/thymoquinone nanoparticles: a promising frontier in asthma therapeutics [PDF]
Nanomedicine JournalObjective(s): To formulate mPEG-PLGA/Thymoquinone nanoparticles for enhanced biological uptake and therapeutic effectiveness of thymoquinone in asthmatic mice induced with ovalbumin (OVA) administration.Materials and Methods: mPEG-PLGA/thymoquinone ...
Mohsen Rahmanian +4 more
doaj +1 more source
Thymoquinone and its therapeutic potentials
Pharmacological Research, 2015 Herbal medicine has attracted great attention in the recent years and is increasingly used as alternatives to chemical drugs. Several lines of evidence support the positive impact of medicinal plants in the prevention and cure of a wide range of diseases. Thymoquinone (TQ) is the most abundant constituent of the volatile oil of Nigella sativa seeds and
Sara, Darakhshan +3 more
openaire +2 more sources
Asian Pacific Journal of Tropical Biomedicine, 2022 Medicinal plants and their ingredients have beneficial effects on human health. Nigella sativa is a herbal plant with multiple biological and pharmacological activities.
Akbar Anaeigoudari
doaj +1 more source
Trakya University Journal of Natural Sciences, 2022 This study aims to explore the cytotoxic, apoptotic and autophagic effects of thymoquinone on human acute myeloid leukemia. The cytotoxic effects of thymoquinone were determined with 3-(4, 5-dimethylthiazol-2-yl)-2 and 5-diphenyltetrazolium bromide (MTT)
Neslihan Tekin Karacaer
doaj +1 more source