Results 21 to 30 of about 13,156 (231)
Protective effect of thymoquinone, the active constituent of Nigella sativa fixed oil, against ethanol toxicity in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Long term consumption of ethanol may induce damage to many organs. Ethanol induces its noxious effects through reactive oxygen species production, and lipid peroxidation and apoptosis induction in different tissues and cell types.
Sayed Masoud Hosseini +5 more
doaj +1 more source
Thymoquinone Protects Against Cardiac Hypertrophy via PPAR-γ/PI3K/Akt Pathway. [PDF]
J Cell Mol MedABSTRACT Thymoquinone (TQ), the principal active constituent of Nigella stativa, has demonstrated numerous biological properties and therapeutic effects on various diseases. However, its therapeutic potential against cardiac hypertrophy remains uncertain.
Qiu RB +10 more
europepmc +2 more sources
AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia [PDF]
, 2017 Thymoquinone is a known inhibitor of neuroinflammation. However, the mechanism(s) involved in its action remain largely unknown. In this study, we investigated the roles of cellular reactive oxygen species (ROS), 5′ AMP-activated protein kinase (AMPK ...
El-Bakoush, Abdelmeneim +4 more
core +1 more source
International Journal of Molecular Sciences, 2022 Cancer is a life-threatening and multifaceted disease. Pioneering research works in the past three decades have mechanistically disentangled intertwined signaling networks which play contributory roles in carcinogenesis and metastasis. Phenomenal strides have been made in leveraging our scientific knowledge altogether to a new level of maturity ...
Ammad Ahmad Farooqi +2 more
openaire +2 more sources
Therapeutic perspective of thymoquinone: A mechanistic treatise [PDF]
Food Science & Nutrition, 2021 AbstractThe higher utilization of fruits and vegetables is well known to cure human maladies due to the presence of bioactive components. Among these compounds, thymoquinone, a monoterpene and significant constituent in the essential oil of Nigella sativa L., has attained attention by the researchers due to their pharmacologies perspectives such as ...
Masood Sadiq Butt +13 more
openaire +2 more sources
High pressure vapour-liquid equilibrium of volatiles in supercritical carbon dioxide [PDF]
, 2013 Binary vapour-liquid equilibrium of thymoquinone and carbon dioxide at the isothermal conditions was carried out at temperature 323.15 K and pressures from 6 to 10 MPa.
Gurgenova, Karina +2 more
core +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2022 Medicinal plants and their ingredients have beneficial effects on human health. Nigella sativa is a herbal plant with multiple biological and pharmacological activities.
Akbar Anaeigoudari
doaj +1 more source
Thymoquinone played a protective role against tartrazine-induced hepatotoxicity [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): The current study, the first of its kind in the literature, aimed to observe the toxic effects of Tartrazine, a commonly used dyestuff in industries and foods, on the liver, and investigate whether this toxicity could be eliminated with ...
Nursena Demircigil +5 more
doaj +1 more source
Scolicidal effects of black cumin seed (Nigella sativa) essential oil on hydatid cysts [PDF]
, 2014 : Surgery remains the preferred treatment for hydatid cyst (cystic echinococcosis, CE). Various scolicidal agents have been used for inactivation of protoscolices during surgery, but most of them are associated with adverse side effects.
Ezatpour, Behrouz. +5 more
core +1 more source
Thymoquinone and its therapeutic potentials
Pharmacological Research, 2015 Herbal medicine has attracted great attention in the recent years and is increasingly used as alternatives to chemical drugs. Several lines of evidence support the positive impact of medicinal plants in the prevention and cure of a wide range of diseases. Thymoquinone (TQ) is the most abundant constituent of the volatile oil of Nigella sativa seeds and
Sara, Darakhshan +3 more
openaire +2 more sources