Results 1 to 10 of about 5,681 (117)
Pharmaceutics, 2022 Thymoquinone has been proved to be effective against neoplasms, including skin cancer. Its high lipophilicity, however, may limit its potential use as a drug.
Patrycja Kłos +2 more
exaly +3 more sources
Combining glycine with thymoquinone offers a promising strategy for diabetes treatment [PDF]
Scientific ReportsDiabetes is increasing globally, and current treatments are frequently associated with high costs and harmful side effects. Researchers are exploring safer, natural alternatives as thymoquinone and glycine. Glycine, the simplest proteinogenic amino acid,
Nourhan N. Bash +3 more
doaj +2 more sources
The healing effects of thymoquinone on experimentally induced traumatic tendinopathy in rabbits
Journal of Orthopaedic Surgery and Research, 2023 Objectives Thymoquinone is a major bioactive compound present in the black seeds of the Nigella sativa. Tendon injuries are almost 50% of all musculoskeletal injuries. The recovery of tendon after surgery has become a significant challenge in orthopedics.
Alireza Soltanfar +4 more
doaj +1 more source
Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells. [PDF]
PLoS ONE, 2010 A major concern of cancer chemotherapy is the side effects caused by the non-specific targeting of both normal and cancerous cells by therapeutic drugs. Much emphasis has been placed on discovering new compounds that target tumour cells more efficiently ...
Resham Lal Gurung +9 more
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Anti-microsporidial effect of thymoquinone on Encephalitozoon intestinalis infection in vitro
Asian Pacific Journal of Tropical Biomedicine, 2020 Objective: To evaluate the anti-microsporidial effects of the active component of Nigella sativa seeds, thymoquinone, against Encephalitozoon intestinalis using an in vitro model.
Ulfet Cetinkaya +2 more
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An Evaluation of the Protective Effects of Thymoquinone on Amikacin-Induced Ototoxicity in Rats [PDF]
Clinical and Experimental Otorhinolaryngology, 2015 ObjectivesIn this study we investigated the probable protective effects of thymoquinone on amikacin-induced ototoxicity in rats.MethodsThirty-two healthy rats were divided into four groups (amikacin, amikacin+thymoquinone, thymoquinone, and no treatment).
Fadlullah Aksoy +6 more
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Effect of Thymoquinone against Aluminum Chloride-Induced Alzheimer-Like Model in Rats [PDF]
Benha Veterinary Medical Journal, 2023 Alzheimer's disease is a progressive neurodegenerative disorder characterized by oxidative stress, neuroinflammation and synaptic dysfunction, which result in part from the abnormal accumulation of senile plaques and neurofibrillary tangles outside and ...
Ahmed elsayed
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Life, 2022 This study investigated the effect of thymoquinone on seeds germination and young seedlings of lentils under cadmium (Cd) stress (300 µM). Three different concentrations (10 µM, 1 µM, and 0.1 µM) of thymoquinone were applied.
Reda Ben Mrid +8 more
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Open Life Sciences, 2023 Thymoquinone is a valuable metabolite derived from the Nigella sativa L. seeds and has a variety of therapeutic properties. Thymoquinone was estimated using n-hexane:ethyl acetate (8:2, v/v) green solvent system and computed at a wavelength of 254 nm ...
Ravi Y. +7 more
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PLoS ONE, 2023 An increasing body of literature demonstrates the therapeutic relevance of polyphenols in eukaryotic cell and animal model studies. The phase II glutathione S-transferases (GST) show differential responses to thymoquinone, a major bioactive polyphenol ...
Nida Alsaffar, Yayin Fang, Eric Walters
doaj +3 more sources