Results 11 to 20 of about 9,080 (213)
The Diepoxides of Thymoquinone
Australian Journal of Chemistry, 1989 Structures for the cis and trans diepoxides of thymoquinone are assigned from n.m.r. and X-ray crystallographic studies.
Carman M.R. +4 more
core +5 more sources
Antibacterial activity of thymoquinone derivative [PDF]
BMC Research Notes, 2023 AbstractNatural products such as terpenoidal compounds have been extremely tested against pathogenic bacteria. Researches are frequently carried out to find out new natural, semisynthetic and synthetic antibacterial agents due to problems of resistance.
Mohammad Yasin +2 more
openaire +5 more sources
Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth. [PDF]
PLoS ONE, 2015 We examined the thymoquinone induced inhibition of purified F1 or membrane bound F1FO E. coli ATP synthase. Both purified F1 and membrane bound F1FO were completely inhibited by thymoquinone with no residual ATPase activity. The process of inhibition was
Zulfiqar Ahmad +2 more
doaj +3 more sources
International Journal of Molecular Sciences, 2022 Cancer is a life-threatening and multifaceted disease. Pioneering research works in the past three decades have mechanistically disentangled intertwined signaling networks which play contributory roles in carcinogenesis and metastasis. Phenomenal strides have been made in leveraging our scientific knowledge altogether to a new level of maturity ...
Ammad Ahmad Farooqi +2 more
openaire +3 more sources
Thymoquinone attenuates doxorubicin‐cardiotoxicity in rats
Journal of Biochemical and Molecular Toxicology, 2020 AbstractContrary to the fact that doxorubicin is a powerful chemotherapeutic agent for the treatment of neoplastic diseases, cardiotoxicity is too important to be ignored. Thymoquinone serves as a powerful free radical scavenger. In the study, the effects of thymoquinone against doxorubicin‐cardiotoxicity will be evaluated. Forty rats were divided into
Derya Karabulut +4 more
openaire +4 more sources
Thymoquinone played a protective role against tartrazine-induced hepatotoxicity [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): The current study, the first of its kind in the literature, aimed to observe the toxic effects of Tartrazine, a commonly used dyestuff in industries and foods, on the liver, and investigate whether this toxicity could be eliminated with ...
Nursena Demircigil +5 more
doaj +2 more sources
Therapeutic Effects of Thymoquinone in a Model of Neuropathic Pain [PDF]
Current Therapeutic Research, 2014 Background: The goal of our study was to determine the therapeutic effects of thymoquinone in a dose-dependent manner in a model of neuropathic pain following an experimentally applied spinal cord injury (SCI).
Feyzi Çelik, MD +8 more
doaj +2 more sources
Effects of thymoquinone on isolated and cellular proteasomes [PDF]
The FEBS Journal, 2010 Thymoquinone, a naturally derived agent, has been shown to possess antioxidant, antiproliferative and proapoptotic activities. In the present study, we explored thymoquinone effects on the proteasomal complex, the major system involved in the removal of damaged, oxidized and misfolded proteins.
CECARINI, Valentina +9 more
core +4 more sources
Attenuation of morphine tolerance and dependence by thymoquinone in mice [PDF]
Avicenna Journal of Phytomedicine, 2016 Objectives: Dependence and tolerance are major restricting factors in the clinical use of opioid analgesics. In the present study, the effects of thymoquinone, the major constituent of Nigella sativa seeds, on morphine dependence and tolerance were ...
Hossein Hosseinzadeh +4 more
doaj +1 more source
Investigation of Thymoquinone as an Inhibitor of CYP2C8/EET Axis. [PDF]
ChembiochemCytochrome P450 2C8 (CYP2C8) is known to cause drug interactions via pharmacokinetic alterations of drugs, but it’s also explicitly crucial for endogenous metabolism, like the generation of epoxyeicosatrienoic acids (EETs) from arachidonic acid.
Dhiman S +9 more
europepmc +2 more sources