Results 11 to 20 of about 13,156 (231)

Is thymoquinone an antioxidant? [PDF]

BMC Pharmacology, 2010
BackgroundThymoquinone is one of the active ingredients of blackcumin (Nigella sativaL.) essential oil possessing anti-inflammatory, antineoplastic, neuro- and hepatoprotec-tive properties. Some of these properties were attributedto an antioxidant activity of thymoquinone, which seemsto be unlikely from its structure. Because the lipophilicthymoquinone
Katrin Staniek, Lars Gille
core   +3 more sources

Antibacterial activity of thymoquinone derivative

BMC Research Notes, 2023
AbstractNatural products such as terpenoidal compounds have been extremely tested against pathogenic bacteria. Researches are frequently carried out to find out new natural, semisynthetic and synthetic antibacterial agents due to problems of resistance.
Mohammad Yasin, Haroon M. Haniffa, M. Iqbal Choudhary   +2 more
openaire   +4 more sources

Thymoquinone effect on the Dictyostelium discoideum model correlates with functional roles for glutathione S-transferases in eukaryotic proliferation, chemotaxis, and development.

PLoS ONE, 2023
An increasing body of literature demonstrates the therapeutic relevance of polyphenols in eukaryotic cell and animal model studies. The phase II glutathione S-transferases (GST) show differential responses to thymoquinone, a major bioactive polyphenol ...
Nida Alsaffar, Yayin Fang, Eric Walters
doaj   +3 more sources

The effect of ultrasound pretreatment on some selected physicochemical properties of black cumin (Nigella Sativa) [PDF]

, 2018
Background In the present study, the effects of ultrasound pretreatment parameters including irradiation time and power on the quantity of the extracted phenolic compounds quantity as well as on some selected physicochemical properties ...
A Jiménez, AM Goula, AOAC, AOCS, AR Jambrak, AS Oktay, B Khadhraoui, BJ Arends, E Halawani, EA Decker, F Chemat, F Chemat, F Chemat, F Yamaguchi, H Bakhshabadi, H Haron, HRH Takruri, IUPAC, JA Carcel, JL Luque-Garcia, JY Lin, L Han, L Zhang, M Corrales, M Ghavami, M Jacotet-Navarro, M Kebriti, M Pinelo, M Toma, M Vintoru, M Virot, PN Giannelos, S Abdullah, S Machmudah, S Samaram, S Zhao, S Zomorrodi, SK Tiruppur Venkatachallam, SR Shirsath, SU Kadam, TJ Mason, W Lingyun, ZS Zhang   +42 more
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Thymoquinone improves folliculogenesis, sexual hormones, gene expression of apoptotic markers and antioxidant enzymes in polycystic ovary syndrome rat model

Veterinary Medicine and Science, 2023
Background Nowadays, polycystic ovary syndrome (PCOS) is a prevalent cause of infertility affecting women of reproductive age around the world. Thymoquinone is a natural antioxidant, derived from Nigella sativa.
Sanaz Alaee, Maryam Mirani, Zahra Derakhshan, Farhad Koohpeyma, Azizollah Bakhtari   +4 more
doaj   +1 more source

Black Cumin Seed Oil Increase Leucocyte and CD4Thelper Number in Sprague-dawley Rats Induced with Dimethylbenzanthracene [PDF]

, 2019
Cigarette smoke contains 7, 12 dimethylbenzanthracene (DMBA). Metabolic of DMBA is immunosuppressive. Black cumin seed oil (BCSO) is an immunomodulation.
Akrom, A. (Akrom), Hidayati, T. (Titiek), Indrayanti, I. (Indrayanti), Sagiran, S. (Sagiran)   +3 more
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Thymoquinone Inhibits Escherichia coli ATP Synthase and Cell Growth. [PDF]

PLoS ONE, 2015
We examined the thymoquinone induced inhibition of purified F1 or membrane bound F1FO E. coli ATP synthase. Both purified F1 and membrane bound F1FO were completely inhibited by thymoquinone with no residual ATPase activity. The process of inhibition was
Zulfiqar Ahmad, Thomas F Laughlin, Ismail O Kady   +2 more
doaj   +1 more source

Thymoquinone Modulates Local MMP-9, IL-10, and IgG in Sciatic Nerve Crush Injury Animal Model

Indonesian Biomedical Journal, 2022
BACKGROUND: Interleukin (IL)-10 is involved in Wallerian degeneration after peripheral nerve crush injury. Oral thymoquinone was previously observed to decrease local immunoglobulin-G (IgG) in a crush-injured rat model. No study has evaluated the pathway
Valentinus Besin, Abdul Hafid Bajamal, I Ketut Sudiana, Mangestuti Agil, Jusak Nugraha, Mohammad Hasan Machfoed, Paulus Budiono Notopuro, Naesilla Naesilla   +7 more
doaj   +1 more source

Black Cumin Seed Oil Antidiabetogenic by Increasing Pancreatic P53 Expression [PDF]

, 2018
Black cumin seed oil (BCSO) contains many thymoquinone and unsaturated fatty acids that act as antioxidants. Thymoquinone was thought to inhibit pancreatic damage and prevent hyperglycemia by involving p53. The study aimed to determine the BCSO effect on
Akrom, A. (Akrom), Darmawan, E. (Endang), Hidayati, T. (Titiek), Nurfadjrin, R. (Rizma)   +3 more
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Renoprotective effect of thymoquinone against rhabdomyolysis-induced acute kidney injury in the rat model [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Rhabdomyolysis leads to the release of myoglobin, sarcoplasmic proteins, and electrolytes into the blood circulation causing acute kidney injury (AKI). Thymoquinone, a natural compound found in Nigella sativa seeds, has antioxidant and anti-
Arezoo Hosseini, Soghra Mehri, Tahereh Aminifard, Mahboobeh Ghasemzadeh Rahbardar, Sadaf Nouripor, Abolfazl Khajavirad, Amirhossein Jafarian, Hossein Hosseinzadeh   +7 more
doaj   +1 more source