Results 71 to 80 of about 9,080 (213)

Ameliorative Effect of Thymoquinone and Thymoquinone Nanoparticles against Diazinon-Induced Hepatic Injury in Rats: A Possible Protection Mechanism

open access: yes, 2023
The health benefits of thymoquinone (TQ) have been a significant focus of numerous studies. However, more research is needed to ascertain whether its nano-form can effectively treat or prevent chronic diseases.
Badriyah S. Alotaibi   +6 more
core   +1 more source

Nanomedicine for the Treatment of Pediatric Type 2 Diabetes: Progress, Challenges, and Translational Perspectives

open access: yesAdvanced Therapeutics, Volume 9, Issue 9, September 2026.
Overview of pharmaceutical nanocarriers in diabetes, illustrating applications of nanotechnology including enhanced drug and targeted drug delivery and nanosensors for glucose monitoring and diagnosis. ABSTRACT Pediatric type 2 diabetes mellitus (T2DM) is rapidly emerging as a critical global health concern, driven largely by rising childhood obesity ...
Nnamdi Ikemefuna Okafor   +2 more
wiley   +1 more source

Effects of Thymoquinone on the Pharmacokinetics and Pharmacodynamics of Glibenclamide in a Rat Model

open access: yesNatural Product Communications, 2015
Glibenclamide and thymoquinone plasma concentrations were analysed using a sensitive RP-HPLC method, and non-compartmental model pharmacokinetic parameters were calculated.
Ajaz Ahmad   +5 more
doaj   +1 more source

Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro.

open access: yesPLoS ONE, 2014
BackgroundThymoquinone is an active ingredient isolated from Nigella sativa (Black Seed). This study aimed to evaluate the in vitro and in vivo anti-leukemic effects of thymoquinone on WEHI-3 cells.Methodology/principal findingsThe cytotoxic effect of ...
Landa Zeenelabdin Ali Salim   +9 more
doaj   +1 more source

Protective Effects of Thymoquinone on Endothelial Cell Dysfunction in Hypercholesterolemia [PDF]

open access: yes
Background: Increased reactive oxygen species (ROS) have been implicated as important mechanisms that contribute to endothelial dysfunction (ED). The administration of thymoquinone in animal models significantly inhibits ROS production.
Giftania Wardani
core   +2 more sources

Evaluation of the antifungal effect of thymoquinone on standard Candida strains and cytotoxicity on the fibroblastic cell line, in vitro study: Short Communication [PDF]

open access: yesمجله دانشگاه علوم پزشکی بیرجند
The present study aimed to assess the antifungal effect and compare different concentrations of thymoquinone on standard Candida strains, including Candida albicans, Candida glabrata, Candida parapsilopsis, and Candida tropicalis, and investigate the ...
Safiyeh Golzar Yadegary   +2 more
doaj  

Optimization of Microwave-assisted Extraction of Thymoquinone from Nigella sativa L. Seeds

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2016
The high potential of thymoquinone as an ingredient and/or additive in the food, pharmaceutical and cosmetic industries has been well established in previous studies.
Erkan Karacabey
doaj   +1 more source

Effects of thymoquinone supplementation on somatostatin secretion in pancreas tissue of rats [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2017
In this study, it was aimed to investigate the effects of thymoquinone (TQ), which is the bioactive phytochemical constituent of the seeds oil of Nigella sativa, on somatostatin secretion in the rat pancreatic tissue by immunohistochemical method ...
BAKIR B   +3 more
doaj   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi   +13 more
wiley   +1 more source

Effect of intraperitoneal thymoquinone on postoperative peritoneal adhesions

open access: yes, 2015
Background: To determine the effect of thymoquinone on adhesion formation in a rat caecotomy/suture model. Materials and Methods: Thirty wistar rats were randomized into three groups: The control group received saline and the thymoquinone group received ...
Arıkanoğlu, Zülfü   +5 more
core   +1 more source

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