Results 171 to 180 of about 304,787 (301)

The NF‐κB transcription factor RelA directs mucosal‐associated invariant T‐cell development

Immunology &Cell Biology, EarlyView.
In this study, we found that the nuclear factor kappa light chain enhancer in activated B cells (NF‐κB) transcription factor RelA, and to a lesser extent NF‐κB1 and NF‐κB2, are key regulators of mucosal‐associated invariant T (MAIT)‐cell development and differentiation.
Thomas S Fulford, Hui‐Fern Koay, Raelene Grumont, Darryl N Johnson, Sebastian Scheer, Hendrik J Nel, Ranjeny Thomas, Jeffrey YW Mak, David P Fairlie, Charis E Teh, Daniel HD Gray, Vanessa L Bryant, Colby Zaph, Lorraine A O'Reilly, Steven Gerondakis, Dale I Godfrey   +15 more
wiley   +1 more source

Increased Levels of Inflammatory Proteins, Including TARC/CCL17, in Skin of AD Patients During JAK Inhibitor Treatment

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 260-263, March 2025.
Celeste M. Boesjes, Lian F. van der Gang, Daphne S. Bakker, C. F. den Hartog Jager, Marlies de Graaf, Marjolein S. de Bruin‐Weller, Femke van Wijk, Edward F. Knol   +7 more
wiley   +1 more source

Biomarkers for therapeutic response and adverse outcomes in atopic dermatitis: A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review assessed 52 biomarkers predicting systemic therapy response and adverse events in atopic dermatitis. Most studies focused on dupilumab, and findings were inconsistent. IgE and eosinophils were largely non‐predictive, though elevated eosinophils and LDH sometimes indicated poorer outcomes.
Eva Hilger, Kaitlyn Chan, Alphonsus Yip, Xingyue Maria Wang, Conor Broderick, Bernd Arents, Karin van Bart, Kilian Eyerich, Joseph Rastrick, Stephan Weidinger, Carsten Flohr, on behalf of the BIOMAP Consortium   +11 more
wiley   +1 more source

miR-194-5p-mediated suppression of protein tyrosine phosphatase non-receptor type 12 (PTPN12) expression in the thymus enhances immunologic functional restoration in aged mice. [PDF]

Eur J Med Res
Ai LY, Zhu MQ, Xu WM, Zou Y, Huang H, Chen K, Shuai X, Hu QH, Guo ZB.   +8 more
europepmc   +1 more source

Effects of Acupuncture as a Therapeutic Intervention Targeting Both Skin and Gastrointestinal Symptoms in Patients With Atopic Dermatitis: A Randomised Controlled Trial

Clinical &Experimental Allergy, EarlyView.
Jundong Kim, Yerin Seo, Mijung Yeom, Su‐Yang Park, Sujin Lee, Sora Ahn, Dae‐Hyun Hahm, Soon‐Kyeong Kwon, Kyuseok Kim, Hi‐Joon Park   +9 more
wiley   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Is Thymic Involution Truly a Deterioration or an Adaptation? [PDF]

Bull Math Biol
Iwasa Y, Hayashi R, Hara A, Matsuo K.
europepmc   +1 more source

Shrubs and trees as natural insect protection for grazing animals in Switzerland and the alpine region: A systematic review of in vitro, in vivo and clinical trials Sträucher und Bäume als natürlicher Insektenschutz für Weidetiere in der Schweiz und im Alpenraum: Eine systematische Literaturübersicht über in vitro‐, in vivo‐ und klinische Studien

Medical and Veterinary Entomology, EarlyView.
Biting or irritating insects are a threat to the health and welfare of grazing animals. This systematic review reveals that several shrubs and bushes growing in the alpine area have insecticidal, insect‐repellent and/or attractant properties. The alder Alnus glutinosa, juniper Juniperus communis, spruce Picea abies and walnut Juglans regia are ...
Theresa Schlittenlacher, Sofie Egli, Michael Walkenhorst, Veronika Maurer   +3 more
wiley   +1 more source

Single-cell transcriptomics reveals diversity and conservation of chicken lymphocytes. [PDF]

Poult Sci
Liu H, Tu J, He X, Ouyang Q, Zhang H.
europepmc   +1 more source

Prevention of Atopic Dermatitis in High‐Risk Infants: A Review of the Role of Lipid‐Based Barrier Repair Therapy

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan, Marty O. Visscher   +1 more
wiley   +1 more source