Results 211 to 220 of about 304,787 (301)

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

Immunology, Volume 177, Issue 4, Page 784-797, April 2026.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si, Gaochen Zhu, Qianling Jiang, Xin Ma, Guan Yang   +4 more
wiley   +1 more source

Lymphoid Organ Architecture and Hematopoiesis Disruption in Spinal Muscular Atrophy: Therapeutic Rescue by SMN Restoration. [PDF]

Int J Mol Sci
Guillamón P, Lindner G, Guillen J, Gatius A, Gras S, Martínez-España L, Piedrafita L, Panosa A, Tapia O, Mora C, Esquerda JE, Tizzano EF, Tarabal O, Calderó J.   +13 more
europepmc   +1 more source

Characterization of a prokaryotic topoisomerase I activity in chloroplast extracts of maize [PDF]

, 1983
Siedlecki, Janusz, Weissbach, Arthur, Zimmermann, Wolfgang   +2 more
core  

Looking for Greener Pastures: In Vitro Screening of Phytogenics for the Control of Sparicotyle chrysophrii in Gilthead Sea Bream

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT The gill parasite Sparicotyle chrysophrii poses a significant threat to gilthead sea bream (Sparus aurata) aquaculture in the Mediterranean, causing considerable mortality and economic losses. As traditional chemotherapeutic treatments, like formalin, face growing regulatory restrictions, there is an urgent need for alternative control ...
Teresa Pirollo, Ana León, Monica Caffara, Alice Caneschi, Itziar Estensoro, Jinni Gu, Maurizio Scozzoli, Ariadna Sitjà‐Bobadilla, Oswaldo Palenzuela   +8 more
wiley   +1 more source

Targeting the LPI/GPR55 Axis in MAFLD and MASH: Novel Insights, Therapeutic Strategies and Future Directions

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD), recently redefined from non‐alcoholic fatty liver disease (NAFLD), highlights the central role of metabolic dysfunction in its pathophysiology. The L‐α‐lysophosphatidylinositol/G protein‐coupled receptor 55 (LPI/GPR55) axis, an element of the endocannabinoidome, has emerged as a key
Jerome Lian, Ricky R Lareu, Mohan Patil, Marco Falasca   +3 more
wiley   +1 more source

Regional and Sex‐Dependent Immune Profiling Across the Colon in A Mouse Model of Ulcerative Colitis

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
At baseline, males have higher IL‐10, TH17 cytokines, and higher macrophages, neutrophils, and CD8+ cells in the medial and distal colon. Whereas females displayed increasing macrophages, lower TNF‐α, and higher IL‐1β, IL‐17A, and dendritic cells in the cecum and proximal colon.
Diane M. Tshikudi, Fola Olayinka‐Adefemi, Fazia Ait Zenati, Christine Zhang, Aaron J. Marshall, Charles N. Berstein, Jean‐Eric Ghia   +6 more
wiley   +1 more source

<i>Thymus apulus</i> (<i>T.</i> sect. <i>Hyphodromi</i>, Lamiaceae), a New Species from Southern Italy. [PDF]

Plants (Basel)
Bartolucci F, Conti F.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, Volume 20, Issue 3, Page 753-778, March 2026.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Aging and Thymosin Alpha-1. [PDF]

Int J Mol Sci
Simonova MA, Ivanov I, Shoshina NS, Komyakova AM, Makarov DA, Baranovskii DS, Klabukov ID, Telepenina KP, Atiakshin DA, Shegay PV, Kaprin AD, Stepanenko VN.   +11 more
europepmc   +1 more source