Results 121 to 130 of about 61,133 (325)

Preclinical Toxicity Screening of Sodium Dodecanoyloxybenzenesulfonate (LOBS) as a New Alternative Biocide Using In Vitro and In Vivo Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Sodium hypochlorite is a well‐established biocide extensively used in both living and industrial environments; however, exposure to it or improper handling can harm the human body and the environment. Thus, safer alternatives to sodium hypochlorite are required.
Seung Eui Min   +3 more
wiley   +1 more source

The physiology of immunology [PDF]

open access: yes, 1992
October 21, 1992."This work was supported in part by grants from the USDA (92-37206-7777) and from the National Institutes of Health (AG06246)"--P. 3.Includes bibliographical references (pages 17-21)
Kelley, Keith W.
core  

Stratum Corneum Ceramide Abnormalities in Atopic Dermatitis: Pathophysiology and Implications for Disease Management

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley   +1 more source

Endocrine Disorders as a Contributory Factor to Neoplasia in SJL/J Mice [PDF]

open access: yes, 2017
We studied the endocrine status of SJL/J mice. Light and electron microscopy revealed that the adenohypophyses of both sexes became progressively infiltrated with an abnormal number of gonadotropinproducing cells that probably secreted large amounts of ...
Bianchi, E.   +5 more
core  

Influence of the thymus and pineal gland on immunity and aging

open access: diamond, 2022
Antoniya Hachmeriyan   +2 more
openalex   +2 more sources

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Undescended retropharyngeal parathyroid adenoma with adjacent thymic tissue in a 13-year-old boy with primary hyperparathyroidism. [PDF]

open access: yes, 2019
We describe a rare presentation of a symptomatic parathyroid adenoma located in an ectopic retropharyngeal position in a 13-year-old boy. Preoperative CT scan and MRI demonstrated the ectopic location of the parathyroid adenoma.
Bickler, Stephen W   +6 more
core  

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Ectopic thymus in the neonatal period: A case report

open access: yesRadiology Case Reports
The thymus, a vital immune organ in humans, plays a crucial role in the differentiation and development of T cells. Its normal development commences around the fourth week of gestation, originating from the ectoderm of the third branchial cleft and the ...
Junyan Wang, Hua Li, Xiaomei Xie
doaj   +1 more source

Pathophysiological aspects of the problem of prolonged hypokinesia [PDF]

open access: yes
The changes in man's acitivity due to modern life with automation and sedentary activities and man's exploration of space in a state of weightlessness have accentuated the importance of hypokinesia.
Kovalenko, Y. A.
core   +1 more source

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