Results 171 to 180 of about 262,172 (291)

Thymic hyperplasia in patients with acromegaly: imaging-based assessment and clinical implications. [PDF]

open access: yesArch Endocrinol Metab
Koylu NY   +6 more
europepmc   +1 more source

Nicotinamide Metabolism Constrains Memory CD8+ T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

open access: yesAdvanced Science, Volume 13, Issue 57, 14 October 2026.
ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang   +13 more
wiley   +1 more source

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

open access: yesAdvanced Science, Volume 13, Issue 58, 19 October 2026.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li   +11 more
wiley   +1 more source

Incidence of Ectopic Parathyroid Glands in Primary, Secondary, and Tertiary Hyperparathyroidism. [PDF]

open access: yesJ Surg Res
Nathani S   +7 more
europepmc   +1 more source

Anti‐Inflammatory Effects of Vicatia thibetica De Boiss. in Rheumatoid Arthritis and Associated Multi‐Pathway Modulation In Vivo

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Vicatia thibetica de Boiss. (VTDB) extracts and fractions were screened for anti‐rheumatoid arthritis activity via UHPLC‐MS, network pharmacology, and CIA rat models. VTDB‐nBuOH stood out, regulating PI3K/Akt, JAK2/STAT3, macrophage polarization, and gut microbiota to relieve joint inflammation, with proteomics verifying its multi‐pathway regulatory ...
Mo‐Zi‐Li Adu   +9 more
wiley   +1 more source

UPLC‐Q‐TOF‐MS/MS Profiling and Synergistic Anti‐HCC Activity of Gallic Acid From Compound Muji Granules Combined With hUC‐MSC‐Exos

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang   +12 more
wiley   +1 more source

Anterior Mediastinal Mature Teratoma Presenting With Mediastinal Mass Syndrome in a Six‐Month‐Old Infant: Diagnostic Pitfalls and Anesthetic Challenges

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT An anterior mediastinal mass in infants can present with life‐threatening complications due to airway and vascular compression. We report a six‐month‐old infant with a mature teratoma presenting as mediastinal mass syndrome, highlighting the diagnostic challenges and anesthetic risks involved.
Ghamar Taj Khanbabaee   +6 more
wiley   +1 more source

Long‐Term Ocular Outcomes of Dupilumab in Atopic Dermatitis: Results From the BioDay Registry

open access: yesClinical and Translational Allergy, Volume 16, Issue 10, October 2026.
ABSTRACT Background Dupilumab‐associated ocular surface disease (DAOSD) is the most reported side effect in dupilumab‐treated atopic dermatitis (AD) patients. We investigated the effect of long‐term dupilumab treatment on ocular surface disease (OSD), conjunctival goblet cells (GCs), and tear fluid dupilumab levels and proteins.
Nienke Veldhuis   +12 more
wiley   +1 more source

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