Results 151 to 160 of about 33,800 (232)

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha   +2 more
wiley   +1 more source

Pretreatment With BTK Inhibitors Improved the Sensitivity of DLBCL Cells to CAR‐T Cells in a Coculture System by Downregulating the Polarisation of M2 Macrophages

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT The tumour microenvironment (TME) of relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) patients is associated with resistance of DLBCL cells to CD19 CAR‐T cells. How to improve TME in DLBCL and improve the efficacy of CAR‐T cell therapy remains to be further explored.
Yao Qi   +6 more
wiley   +1 more source

Evidence that S‐phase kinase associated protein 2 (SKP2) is ubiquitinated and degraded via a Rho‐related BTB domain containing 1 (RhoBTB1) and Cullin‐3 mechanism in placenta

open access: yesPhysiological Reports, Volume 14, Issue 15, August 2026.
Graphical representation of mechanism by which RhoBTB1 regulates SKP2. Abstract Rho related BTB domain containing 1 (RhoBTB1) is highly expressed in placenta and functions to deliver protein targets to the Cullin‐3 (CUL3) E3 ubiquitin ligase where they are targeted for ubiquitination and degradation.
Alina L. Tvina   +11 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) for chickens for fattening and chickens reared for laying (Huvepharma N.V.)

open access: yesEFSA Journal, Volume 24, Issue 8, August 2026.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) as a coccidiostat for chickens for fattening and chickens reared for laying.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +28 more
wiley   +1 more source

Sema3E‐plexinD1 Axis Is a Modulator of Foxp3+ Regulatory T‐Cells in House Dust Mite Model of Asthma

open access: yesThe FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Airway epithelial‐derived Sema3E enhances both the number and proliferation of Foxp3+ regulatory T (Treg) cells in an acute model of asthma. Mechanistically, deletion of PlexinD1, the receptor for Sema3E, specifically in Foxp3+ cells was associated with a breakdown in immune regulation in this model.
Mojdeh Matloubi   +6 more
wiley   +1 more source

Regulatory T cells in primary sjögren disease: regulatory mechanisms and therapeutic prospects. [PDF]

open access: yesFront Immunol
Chengzhi W   +5 more
europepmc   +1 more source

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