Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Ectopic parathyroid adenoma posterior to the trachea in the superior mediastinum causing refractory primary hyperparathyroidism: a case report. [PDF]
Yang L +5 more
europepmc +1 more source
ABSTRACT The tumour microenvironment (TME) of relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) patients is associated with resistance of DLBCL cells to CD19 CAR‐T cells. How to improve TME in DLBCL and improve the efficacy of CAR‐T cell therapy remains to be further explored.
Yao Qi +6 more
wiley +1 more source
Emerging concepts in salivary tumor pathology: lessons learned from overlaps with non-salivary organs. [PDF]
Agaimy A, Ihrler S.
europepmc +1 more source
Graphical representation of mechanism by which RhoBTB1 regulates SKP2. Abstract Rho related BTB domain containing 1 (RhoBTB1) is highly expressed in placenta and functions to deliver protein targets to the Cullin‐3 (CUL3) E3 ubiquitin ligase where they are targeted for ubiquitination and degradation.
Alina L. Tvina +11 more
wiley +1 more source
Thymus-like phenotype in benign lymphoepithelial neoplasms of salivary glands: clinicopathological and molecular characterization and reappraisal of relationship to non-sebaceous lymphadenoma. [PDF]
Agaimy A +5 more
europepmc +1 more source
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) as a coccidiostat for chickens for fattening and chickens reared for laying.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +28 more
wiley +1 more source
Sema3E‐plexinD1 Axis Is a Modulator of Foxp3+ Regulatory T‐Cells in House Dust Mite Model of Asthma
Airway epithelial‐derived Sema3E enhances both the number and proliferation of Foxp3+ regulatory T (Treg) cells in an acute model of asthma. Mechanistically, deletion of PlexinD1, the receptor for Sema3E, specifically in Foxp3+ cells was associated with a breakdown in immune regulation in this model.
Mojdeh Matloubi +6 more
wiley +1 more source
The relationships between diabetic male infertility, diabetic cognitive impairment, and the neuroendocrine-immune network: A review. [PDF]
Cao SM +6 more
europepmc +1 more source
Regulatory T cells in primary sjögren disease: regulatory mechanisms and therapeutic prospects. [PDF]
Chengzhi W +5 more
europepmc +1 more source

