Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles [PDF]
Notch is a highly conserved transmembrane protein that is involved in cell fate decisions and is found in organisms ranging from Drosophila to humans. A human homologue of Notch, TAN1, was initially identified at the chromosomal breakpoint of a subset of
Aster, Jon C. +6 more
core
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages [PDF]
Genetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)‐induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy.
Barleon +47 more
core +1 more source
Birth season and environmental influences on blood leucocyte and lymphocyte subpopulations in rural Gambian infants. [PDF]
BACKGROUND: In rural Gambia, birth season predicts infection-related adult mortality, providing evidence that seasonal factors in early life may programme immune development.
Collinson, Andrew C +4 more
core +3 more sources
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development. [PDF]
BACKGROUND: We present the genome sequence of the tammar wallaby, Macropus eugenii, which is a member of the kangaroo family and the first representative of the iconic hopping mammals that symbolize Australia to be sequenced.
Al Nadaf, Shafagh +103 more
core +13 more sources
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan +7 more
wiley +1 more source
Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad +8 more
wiley +1 more source
Humphrey Center News: Fall 1989 v. 4, no. 2 [PDF]
Newsletter of the Hubert H.
Anthony, Richard P. +1 more
core
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
core +2 more sources
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source

