Results 121 to 130 of about 45,884 (303)
Involution and neoplasms of the thymus.
In vivo (Athens, Greece), 2000 Mammalian ontogenesis and postnatal histogenesis involves the dynamic and appropriate interaction of two growth related phenomena: progression and regression. The thymus gland is the organ of the mammalian body that exhibits the most profound involution during normal postnatal histogenesis.
H E, Kaiser +3 more
openaire +1 more source
Food Safety and Health, EarlyView.Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie +3 more
wiley +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Mass Spectrometry Reviews, EarlyView.Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery
Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá +4 more
wiley +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
The Journal of Dermatology, EarlyView.ABSTRACT Atopic dermatitis (AD) essentially exhibits dysbiosis of skin fungal microbiome, mycobiome, characterized by depletion of Malassezia. The effects of recent systemic therapies for AD on skin mycobiome were not understood enough. We examined changes of skin mycobiome before and after systemic treatments with anti‐IL‐4Rα antibody (dupilumab: DUP)
Yuta Koike +5 more
wiley +1 more source
Evaluation of clinical, morphological and pathohistological characteristics of thymomas: Our ten year experience [PDF]
Archive of Oncology, 2017 Background. Thymomas are rare neoplasms arising from tissue elements of the thymus. The objective of the study was to analyse clinical characteristics of patients with thymoma, as well as morphological and patohistological features of neoplasms. Methods:
Lovrenski Aleksandra +5 more
doaj
The Journal of Dermatology, EarlyView.ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley +1 more source
Andrology, EarlyView.Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source