Results 171 to 180 of about 409,890 (320)

A Data‐Driven Epigenetic Characterization of Morning Fatigue Severity in Oncology Patients Receiving Chemotherapy: Associations With Epigenetic Age Acceleration, Blood Cell Types, and Expression‐Associated Methylation

open access: yesCancer Medicine, Volume 14, Issue 15, August 2025.
Fatigue is commonly associated with cancer and its treatments and has a negative impact on patients' ability to tolerate treatments and on their quality of life. This epigenetic characterization of morning fatigue in patients receiving chemotherapy finds biological aging, gene regulatory, and inflammatory processes associated with morning fatigue ...
Caroline Le   +21 more
wiley   +1 more source

Brain metastases from a thymoma: Case report for a rare secondary localization

open access: yesRadiology Case Reports
Thymomas are benign epithelial neoplasms originating from the thymus gland and are among the most common primary mediastinal tumors. Malignancy is typically determined by evidence of pathological invasion beyond the capsule, with local invasion being the
Ghassen Gader   +6 more
doaj  

Dose Selection for DuoBody®‐CD40x4‐1BB (GEN1042/BNT312) Using a mPBPK/RO Model Leveraging Preclinical and Clinical Data

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 418-427, August 2025.
Optimizing target engagement for bispecific antibodies (bsAbs) is challenging, as bsAbs bind to two different targets in vivo to form a trimolecular complex (trimer), and likely display a bell‐shaped concentration–response curve. bsAbs trimer formation is expected to be related to efficacy and safety, and determining the dose level at which it is ...
Gaurav Bajaj   +16 more
wiley   +1 more source

Hepatocellular carcinoma escapes immune surveillance through deceiving thymus into recalling peripheral activated CD8<sup>+</sup> T cells. [PDF]

open access: yesNeoplasia
Hu Q   +18 more
europepmc   +1 more source

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

open access: yesESC Heart Failure, Volume 12, Issue 4, Page 2404-2416, August 2025.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna   +4 more
wiley   +1 more source

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms: Systemic Therapy - Chemotherapy

open access: yesNeuroendocrinology, 2017
R. García-Carbonero   +15 more
semanticscholar   +1 more source

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