Results 181 to 190 of about 45,884 (303)

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage

Aging Cell, Volume 25, Issue 2, February 2026.
Using in vitro DNA damage assays in human T cells, ex vivo profiling of aged immune subsets and a small placebo‐controlled in vivo study, authors show that low‐dose rapamycin, a potent life‐extending mTOR inhibitor, enhances resilience against DNA damage in the human immune system.
Loren Kell, Eleanor J. Jones, Nima Gharahdaghi, Daniel J. Wilkinson, Kenneth Smith, Philip J. Atherton, Anna K. Simon, Lynne S. Cox, Ghada Alsaleh   +8 more
wiley   +1 more source

Extended Thymectomy via Thoracoscopy and Cervical Incision in a Child with Anterior Mediastinal Mixed Germ Cell Tumor and Paraneoplastic Precocious Puberty. [PDF]

Surg Case Rep
Yamoto M, Sugai Y, Gohda Y, Miyake H, Nomura A, Fukumoto K, Sano S, Iwafuchi H, Watanabe K.   +8 more
europepmc   +1 more source

Aging Reshapes γ/δ T‐Cell Immunity Through a Type I Interferon–Foxo1 Axis

Aging Cell, Volume 25, Issue 2, February 2026.
Aging reshapes the peripheral γ/δ T‐cell compartment by promoting the expansion and enhanced IL‐17–driven activity of innate‐like γ/δ T cells in secondary lymphoid organs. This remodeling is controlled by type I interferon–dependent downregulation of Foxo1, linking aging to heightened pro‐inflammatory γ/δ T‐cell responses.
Aurélie Durand, Sarah Porte, Eryang Xing, Christian Wu, Agnès Le Bon, Cédric Auffray, Bruno Lucas, Bruno Martin   +7 more
wiley   +1 more source

Thymic Neuroendocrine Tumor Presenting With Cervical Lymphadenopathy: A Case Report and Diagnostic Challenge. [PDF]

Clin Case Rep
Xie X, Tang J, Wang W, Yang D, Qin K.
europepmc   +1 more source

1‐Year Clinical Outcome Post‐Myasthenic Crisis: A Multicenter Prospective Study in China

European Journal of Neurology, Volume 33, Issue 2, February 2026.
In this prospective cohort of 282 patients with myasthenic crisis (MC) episodes, all‐cause mortality was 15.16%. Among 247 patients who have completed 1‐year follow‐up, 79.76% achieved favorable outcomes with significant improvement in the MG‐activities of daily living (MG‐ADL) score.
Xiao Huan, Ran Chen, Lei Jin, Yuan Wang, Yafang Xu, Lei Yang, Caihua Xi, Jianming Zheng, Lijun Luo, Song Yang, Jianquan Shi, Yanping Liu, Zhe Ruan, Wanlong Wu, Wei Li, Yaoxian Yue, Yarong Li, Wenji Jia, Huahua Zhong, Chong Yan, Jie Song, Jianying Xi, Song Tan, Qilong Jiang, Zhangyu Zou, Chongbo Zhao, Sushan Luo, on behalf of the Chinese Myasthenia Gravis Collaborating Group (CMGCG), Yuzhou Guan, Yuwei Da, Huan Yang, Ting Chang, Yuge Wang, Bitao Bu, Hongyu Zhou, Chunsheng Yang, Hua Zhang, Hui Deng, Ruisheng Duan   +38 more
wiley   +1 more source

Primary poorly differentiated enteric-type adenocarcinoma of the thymus with characteristic intracytoplasmic vacuoles on cytology. [PDF]

Respir Med Case Rep
Tachibana M, Hirota T, Uehara M, Tsukamoto K, Ishikawa R, Tsuchida T.   +5 more
europepmc   +1 more source

PLoS One [PDF]

, 2012
Alles, J., Barth, S., Cogliatti, S., Dueck, A., Grasser, F., Imig, J., Meister, G., Motsch, N., Reineke, T., Renner, C., Tinguely, M., Zhu, J.   +11 more
core   +1 more source

Pathologic assessment of resected stage III non‐small cell lung cancer after neoadjuvant chemotherapy: identification of additional prognostic factors

Histopathology, Volume 88, Issue 3, Page 710-728, February 2026.
Multiple pathological variables are associated with prognosis in resected NSCLC at stage III undergoing neoadjuvant treatment, namely vascular, perineural and pleural infiltration, proliferation index, pathological response, fibrosis and presence of lymphocytes in the tumour bed.
Francesca Lunardi, Alessandra Ferro, Luca Vedovelli, Federica Pezzuto, Sofia‐Eleni Tzorakoleftheraki, Asuman Kilitci, Yuliia Kuzyk, Simone Zanella, Marco Schiavon, Federico Rea, Giulia Pasello, Fiorella Calabrese   +11 more
wiley   +1 more source

Identification of immune cells in benign and malignant thymus tumors: a Mendelian randomization study. [PDF]

Ann Med Surg (Lond)
Yan N, Wang S, Ruan L, Zhang Y, Zhang D, Hu S, Xiong W, Zhang W, Yao C, Wei Y.   +9 more
europepmc   +1 more source

HLA‐DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate‐Pulsing

HLA, Volume 107, Issue 2, February 2026.
ABSTRACT The anti‐tumour immune response plays a pivotal role in eliminating tumour cells, with the presence of tumour‐infiltrating lymphocytes (TILs) often correlated with improved patient outcomes. Among these, CD4+ T lymphocytes act as key orchestrators of the immune response, functioning as effector and regulatory cells, and are essential for ...
Gonzalo Lázaro, Juan A. Cedano, Maitane Faus, Carme Roura‐Mir, Laia Garrigós, José Pérez‐García, Javier Román‐García, Javier Cortés, Andrea Aran, Mercè Martí   +9 more
wiley   +1 more source