Results 191 to 200 of about 409,890 (320)

Type 1 Diabetes: A Guide to Autoimmune Mechanisms for Clinicians

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S6, Page 40-56, August 2025.
Abstract Type 1 diabetes (T1D) results from the destruction of pancreatic beta cells by autoreactive T lymphocytes, leading to insulin deficiency and lifelong insulin dependence. It develops in genetically predisposed individuals, triggered by environmental or immunological factors.
François‐Xavier Mauvais   +1 more
wiley   +1 more source

Beyond the Surface: Investigating the Potential Mechanisms of Non‐Motor Symptoms in Myasthenia Gravis

open access: yesEuropean Journal of Neurology, Volume 32, Issue 8, August 2025.
We review the non‐motor symptoms of MG and their potential pathogenesis, hoping to contribute to personalized diagnosis and treatment. ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder affecting the neuromuscular junction (NMJ), driven by T cells, mediated by B cells, and dependent on autoantibodies.
Benqiao Wang   +3 more
wiley   +1 more source

Diagnostic challenges of FNA cytology of SETTLE: a case report and review of the literature. [PDF]

open access: yesDiagn Pathol
Ilori EO   +5 more
europepmc   +1 more source

Significance of stereologically spatiotemporal cells in molecular medicine

open access: yes
Clinical and Translational Discovery, Volume 5, Issue 4, August 2025.
Xuanqi Liu   +5 more
wiley   +1 more source

Redefining the Immunobiology of Organ Transplantation for New Clinical Horizons

open access: yesScandinavian Journal of Immunology, Volume 102, Issue 2, August 2025.
ABSTRACT Traditional organ transplantation relies on the Self–Non‐self (SNS) model of immunity, focusing on donor–recipient compatibility and aggressive immunosuppression to prevent acute rejection. Although effective early, this strategy does not prevent chronic rejection and cannot account for operational tolerance, failure of perfectly HLA‐matched ...
Masoud H. Manjili
wiley   +1 more source

Use and reporting of historical control data for regulatory studies

open access: yesEFSA Journal, Volume 23, Issue 8, August 2025.
Abstract The provision of historical control data (HCD) is a data requirement for pesticide active substances established by European legislation. HCD are data from studies conducted under the same or similar conditions as the toxicity study under assessment (index study). The collation, use and interpretation of HCD is currently not harmonised.
EFSA Panel on Plant Protection Products and their Residues (PPR)   +22 more
wiley   +1 more source

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