Results 31 to 40 of about 97,265 (298)

A case of ulcerative colitis associated with teprotumumab treatment for thyroid eye disease

open access: yesAmerican Journal of Ophthalmology Case Reports, 2021
Purpose: To present a case of ulcerative colitis associated with teprotumumab treatment for thyroid eye disease. Observations: A 46-year-old Indian female was treated with teprotumumab (Tepezza) for severe thyroid eye disease within 9 months of diagnosis.
Myra B. Safo, Rona Z. Silkiss
doaj   +1 more source

A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]

open access: yes, 1994
Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Bahn, Rebecca S.   +3 more
core   +1 more source

Effects of teprotumumab on patients with long-standing, active thyroid eye disease

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: Describe five cases of long-standing, active thyroid eye disease that responded to treatment with teprotumumab. Observations: Five patients with a greater than 9-month-history of thyroid eye disease, including two patients who had previously ...
Kyle B. Vinson, MD, Maria Kirzhner, MD
doaj   +1 more source

Unilateral proptosis in a patient with thyroid eye disease: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Unilateral proptosis is an abnormality in which one eye sticks out forward more than the other. Bulging of the eye is commonly seen in Graves’ ophthalmopathy, but it’s mostly bilateral.
Himal Bikram Bhattarai   +9 more
doaj   +1 more source

Thyroid eye disease: Etiopathogenesis and management

open access: yesTNOA Journal of Ophthalmic Science and Research, 2022
Thyroid eye disease has been a well-recognized clinical entity related to thyroid gland dysfunction for more than a century. However, the last couple of decades devoted to specific clinical research regarding this entity has significantly contributed to ...
G Seethapathy, V G Madanagopalan
doaj   +1 more source

Significant Role of Thyroid Stimulating Hormone in the Clinical Activity Score of Thyroid Eye Disease at a Tertiary Hospital in Surabaya, Indonesia

open access: yesFolia Medica Indonesiana
Highlights: 1. This study, conducted at a tertiary hospital, was the first to analyze the correlation between thyroid status and clinical activity score in thyroid eye disease. 2.
Hasna Shahida Amatlulloh   +4 more
doaj   +1 more source

How patients experience thyroid eye disease

open access: yesFrontiers in Endocrinology, 2023
ObjectiveTo determine the impact of thyroid eye disease (TED) on patients in various stages of the disease.BackgroundTED is a debilitating and potentially sight-threatening inflammatory autoimmune disease that is frequently misdiagnosed.
Terry J. Smith   +8 more
doaj   +1 more source

Jod-Basedow phenomenon: Reactivation of thyroid eye disease after contrast computed tomography

open access: yesAfrican Vision and Eye Health, 2018
To report a case of Jod-Basedow phenomenon, where a patient with quiescent thyroid eye disease became active after a contrast computed tomography (CT).
Roland Hollhumer, Francesca Indiveri
doaj   +1 more source

Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis [PDF]

open access: yes, 2006
Galectin (Gal)-1, an endogenous lectin found at sites of immune privilege, plays a critical role in the regulation of the immune response. Therapeutic administration of Gal-1 or its genetic delivery suppresses chronic inflammation in experimental models ...
Bianco, German Ariel   +6 more
core   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

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