Teprotumumab for non-inflammatory thyroid eye disease (TED): evidence for increased IGF-1R expression. [PDF]
Teprotumumab, a blocking antibody to the insulin like growth factor 1 receptor (IGF-1R) has been shown to significantly reduce proptosis in recent phase 2 and 3 trials in patients with inflammatory thyroid eye disease (TED). Herein, we investigate the impact of teprotumumab on patients with non-inflammatory TED.
Ugradar S +5 more
europepmc +3 more sources
The “Quiet TED”—A Special Subgroup of Thyroid Eye Disease
Purpose: Thyroid eye disease (TED) or Graves’ orbitopathy starts with an active inflammatory stage (active disease) followed by resolution of inflammation and progression to a fibrotic, inactive stage. In our practice, we have encountered cases that have not had active disease despite presence of fibrotic sequelae and disease ...
Nicole M, Iñiguez-Ariza +3 more
openaire +3 more sources
Impacts of Thyroid Eye Disease (TED), Beyond the Signs and Symptoms: Results from the ElevaTED Patient Survey. [PDF]
Thyroid eye disease (TED) can be visually debilitating and cosmetically disfiguring. Symptoms vary in severity and can lead to drastically impaired quality of life (QoL), ability to work, and mental health. The ElevaTED survey was developed to characterize impacts of TED on QoL, mental health, activities of daily living, sleep, work, and treatment ...
Abrams JG +6 more
europepmc +3 more sources
Comment on ‘Acute thyroid eye disease (TED): Principles of medical and surgical management’ [PDF]
Comment on ‘Acute thyroid eye disease (TED): Principles of medical and surgical management’
A S, Litwin, R, Malhotra
openaire +2 more sources
Thyroid-Associated Ophthalmopathy in Iranian Patients [PDF]
We determined the frequency of clinical thyroid ophthalmopathy in Iranian patients. This crosssectional study was performed at the Endocrinology Institute of Tehran University of Medical Sciences.
Mohsen Bahmani Kashkouli +6 more
doaj +1 more source
Unmasking Orbital Myopathy: When Enlarged Extraocular Muscles Indicate More Than Thyroid Eye Disease: Report of Two Cases. [PDF]
Introduction Orbital myopathy is a condition involving the extraocular muscles, and establishment of a differential diagnosis is crucial to determine its etiology. However, the broad spectrum of the etiologies and the overlap in their clinical and radiological findings often make the diagnosis challenging.
Shinohara D, Abumanhal M, Takahashi Y.
europepmc +2 more sources
THRYOID EYE DISEASE (TED) - A Current Understanding [PDF]
Thyroid Eye Disease (TED) provides a clinical meeting place for physician, ophthalmologist and immunologist. Some past difficulties in understanding this disease may have reflected too narrow specialization. In this presentation only three eponymous terms will be used --Graves' Disease, Plummer's Disease and Hashimoto's Disease.
openaire +2 more sources
Thyroid eye disease (TED) refers to the ocular symptoms and signs caused by an autoimmune pathology affecting the thyroid gland and the orbit. It is most commonly seen in patients with Graves' disease and rarely with Hashimoto's thyroiditis (HT).
Manju Meena, Arcot S Karthikeyan
doaj +1 more source
Glabellar Rhytids in Thyroid Eye Disease: Severity and Their Impact on Emotional Perception [PDF]
ABSTRACT Purpose To quantify glabellar rhytid severity in patients with Thyroid Eye Disease (TED) compared to age‐and sex‐matched controls and to evaluate its impact on external emotional perception. Methods A matched case–control study was performed comparing patients with TED of at least 6 months duration to controls (healthy individuals with no ...
Kaur M, Rivera N, Lazarus S, Wester S.
europepmc +2 more sources
An algorithmic approach in the diagnosis and management of thyroid eye disease
Thyroid eye disease (TED) or Graves ophthalmopathy is commonly associated with thyroid dysfunction and often causes a debilitating effect on the individual.
Akshay G Nair, Savari T Desai
doaj +1 more source

