A data-driven approach for the discovery of biomarkers associated with thyroid eye disease
Background Thyroid eye disease (TED) is the most common autoimmune disease and usually occurs in patients with hyperthyroidism. In this disease, eye-related tissue, such as eye muscles, eyelids, tear glands, etc., become inflated, which causes the eyes ...
Huihui Zou +3 more
doaj +1 more source
Lateral and superior orbital wall autodecompression in a patient with thyroid eye disease
Orbital autodecompression was reported previously in thyroid eye disease (TED). The reports principally focused on spontaneous orbital wall fractures or medial and inferior orbital wall expansion. This report introduces a 66-year-old man, a known case of
Behzad Khademi, Elham Sadeghi
doaj +1 more source
Tear film break-up patterns in thyroid eye disease
Evaluation of tear film break-up pattern (TFBUP) is the main diagnostic method for tear film-oriented therapy (TFOT) of dry eye. This prospective, observational study examined TFBUPs in 154 eyes/sides from 78 patients with thyroid eye disease (TED) who ...
Yasuhiro Takahashi +4 more
doaj +1 more source
Risk of Refractive Prediction Error After Cataract Surgery in Patients with Thyroid Eye Disease
Anne Strong Caldwell,1 Jennifer L Patnaik,1 Melisa Ackerman,1 Karen L Christopher,1 Anne M Lynch,1 Jasleen K Singh2 1Department of Ophthalmology, University of Colorado School of Medicine, Aurora, CO, USA; 2Department of Ophthalmology, Children’s ...
Strong Caldwell A +5 more
doaj
Prevalence of Thyroid Eye Disease Among Thyroid Disorder Patients [PDF]
Aim: To assess the prevalence of Thyroid Eye Disease among thyroid disorder patients. Introduction: Thyroid Eye Disease (TED) is a debilitating autoimmune disorder seen in hyperthyroid, hypothyroid and euthyroid patients.
Veeramani , Panimalar A +2 more
core +1 more source
Abstract Background Teprotumumab, an FDA-approved insulin-like growth factor-1 receptor inhibitor for TED, improves proptosis, diplopia, inflammation, and quality of life. In the pooled phase 2 and 3 trial analysis, 8/84 (10%) teprotumumab-treated patients reported hyperglycemia adverse events (AEs ...
Smith, Terry J +6 more
openaire +1 more source
A ‘Real Life’ Service Evaluation Model for Multidisciplinary Thyroid Eye Services
Background/AimsThere is no universal consensus on the practical implementation and evaluation of the Amsterdam Declaration on Graves Orbitopathy in a Multidisciplinary Thyroid Eye Disease (MDTED) pathway.
Soma Farag +13 more
doaj +1 more source
Prognostic indicators for the development of strabismus among patients with graves’ ophthalmopathy
Objective: Thyroid eye disease (TED), an autoimmune inflammatory process involving the orbital tissues around the eye, is the most common extra-thyroidal manifestation of Graves’ disease (GD). Due to changes in the patient’s appearance, TED is a socially
Tiffany Y. Lin +4 more
doaj +1 more source
The Role of the Immune Response in the Pathogenesis of Thyroid Eye Disease: A Reassessment. [PDF]
Although thyroid eye disease is a common complication of Graves' disease, the pathogenesis of the orbital disease is poorly understood. Most authorities implicate the immune response as an important causal factor.
James T Rosenbaum +28 more
doaj +1 more source
The role of pain in Graves' orbitopathy: Associations with clinical activity and quality of life
Abstract Purpose Pain is included in the clinical activity score (CAS) as an indicator of inflammatory activity in Graves' orbitopathy (GO), yet its clinical relevance has not been systematically evaluated. We therefore investigated the relationship between pain, other inflammatory signs and quality of life (QoL), and assessed the effect of intravenous
Gijsbert J. Hötte +7 more
wiley +1 more source

