Results 61 to 70 of about 5,666,574 (155)

Exploring the Therapeutic Mechanism of Xiehuo Pingtu San in Treating Thyroid Eye Disease Based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Background Xiehuo Pingtu San (XHPTS) has been shown to be safe and effective in treating thyroid eye disease (TED), yet its underlying mechanisms remain unclear. This study aimed to elucidate the active ingredients of XHPTS and their therapeutic mechanisms in TED through network pharmacology, molecular docking, and molecular dynamics simulations ...
Ping Wang, Ruiyan Liu, Xin Shang, Yu Fu, Ying Wang, Shuxun Yan, Suraiya Saleem   +6 more
wiley   +1 more source

Thyroid Eye Disease Following SARS-CoV-2 Vaccination: Experience of a Case Series

Vaccines
Background: Thyroid eye disease (TED), or Graves’ orbitopathy, is the most common extra-thyroidal manifestation of Graves’ disease, but it has only rarely been reported after SARS-CoV-2 vaccination.
Alin Abreu Lomba, María Elena Tello-Cajiao, Mónica Morales, Alexander Martínez, Mauricio Andrés Salazar Moreno, David Alexander Vernaza Trujillo, Alice Gaibor-Pazmiño, Juan S. Izquierdo-Condoy   +7 more
doaj   +1 more source

Early Low‐Dose Rituximab for Mild‐to‐Moderate Thyroid Eye Disease: A Preliminary Evaluation of Efficacy and Safety

International Journal of Endocrinology, Volume 2026, Issue 1, 2026.
Background Thyroid eye disease (TED) is an autoimmune inflammatory condition linked to thyroid dysfunction, which can result in disfigurement and potential vision loss. Recently, immunomodulatory therapies such as rituximab have demonstrated potential benefit in managing TED.
Ming Lu, Luqiang Wang, Xuelian Zhang, Suraiya Saleem   +3 more
wiley   +1 more source

Effect and Durability of Teprotumumab on Optic Neuropathy Secondary to Thyroid Eye Disease (TED CON)

, 2021
To describe the durability of visual improvement in patients with thyroid eye disease (TED)-related compressive optic neuropathy (CON) treated with ...
Connie Sears; Julia Kang; Yao Wang; Andrea Kossler; Roger Turbin; Prem Subramanian; Raymond Douglas; Kimberly Cockerham
core  

A comparison between bilateral and unilateral thyroid eye disease

, 2023
Purpose To compare characteristics of unilateral vs. bilateral thyroid eye disease (TED). Methods This retrospective analytical cross-sectional study was conducted on patients with TED who were evaluated at an academic referral center over a 6-year ...
Mohsen Pourazizi, Pourazizi, M., Iman Mohammadbeigy, Mohammadbeigy, I., Maryam Abbasi, Eshraghi, B., Abbasi, M., Bahram Eshraghi   +7 more
core   +1 more source

International Symposium for Thyroid Eye Disease (June 2016, London)

Клиническая и экспериментальная тиреоидология, 2017
In June 2016, an International Symposium dedicated to the cutting edge research and achievements in Thyroid Eye Disease (TED) diagnosis and treatment was held in London. The symposium was organized by the International Thyroid Eye Disease (ITEDs). It was
Natalia Y. Sviridenko, Marina S. Sheremeta, Yaroslav O. Grusha   +2 more
doaj   +1 more source

Exploring the Potential Roles of Oxidative Stress–Related Genes in Thyroid Eye Disease and Graves’ Disease

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Purpose To reveal the significance of oxidative stress–related genes in the pathogenesis of thyroid eye disease (TED) and Graves’ disease (GD) using a bioinformatics approach. Methods Utilizing datasets from the GEO database, we used the “limma” package to detect differentially expressed genes (DEGs). Oxidative stress–related DEGs related to TED and GD
Weili Zhang, Qinying Huang, Jinying Li, Srijoni Sengupta   +3 more
wiley   +1 more source

Severe thyroid eye disease associated with primary hypothyroidism and thyroid-associated dermopathy

Four unusual cases of patients are described with severe thyroid eye disease (TED) who presented with primary hypothyroidism and thyroid- associated dermopathy (TAD). All four patients had moderate or severe TED and elevated circulating thyrotropin (TSH)
Gleeson H, Fleck B, Dickinson J, Kelly W, Toft A, Kendall-Taylor P, Perros P   +6 more
core   +5 more sources

Selenium supplementation in thyroid eye disease: an updated review from a clinical ophthalmic perspective

, 2023
Thyroid eye disease (TED) consists of a spectrum of autoimmune orbital pathology that threatens patients\u27 quality of life and vision. Research suggests that oxidative stress plays a role in both the thyroid gland and orbit.
Mansour, Tamer N, Maliakkal Hernandez, Janice, Foos, William   +2 more
core   +1 more source

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng, Jinwei Cheng, Guiling Liang, Xiaorui Wang, Yanwen Ge, Jiapei Liu, Luwei Cai, Hui Ying, Fenfen Wang, Jing Hu, Yufan Wang, Philipp E. Scherer, Ben Zhou, Mengle Shao, Fang Zhang   +14 more
wiley   +1 more source