Results 1 to 10 of about 335,864 (307)
Resistance to thyroid hormone beta (R243Q) with autoimmune primary hypothyroidism: report of a kindred [PDF]
Archives of Endocrinology and MetabolismThe syndrome of resistance to thyroid hormone beta (RTHβ) is characterized by impaired tissue responsiveness to thyroid hormone and manifests as non-suppressed thyrotropin despite elevated thyroid hormone levels.
Alpesh Goyal, Rahul Gupta, Rekha Singh
doaj +2 more sources
Functional role of THRAP3 in modulating thyroid hormone-mediated gene networks in C2C12 myotubes. [PDF]
PLoS ONEThyroid hormone (TH) secreted by the thyroid gland plays essential roles in regulating metabolism, development, and nervous system function. Thyroid hormone receptor-associated protein 3 (THRAP3) is a nuclear coactivator that interacts with the thyroid ...
Taku Fukushima +6 more
doaj +2 more sources
Investigating factors associated with thyroid hormone measurements during pregnancy [PDF]
European Thyroid JournalBackground: Accurate assessment of thyroid status is essential for maternal and fetal management during pregnancy. This study measured human chorionic gonadotropin (HCG), albumin, and thyroxine-binding globulin (TBG) levels during pregnancy to clarify ...
Miho Fukushita +13 more
doaj +2 more sources
Hashimoto’s thyroiditis and thyroid hormone sensitivity in euthyroid individuals: their association with carotid plaque in northeast China [PDF]
Frontiers in EndocrinologyBackgroundCarotid plaque is a hallmark of systemic atherosclerosis, which underlies the pathology of cardiovascular and cerebrovascular events. Both thyroid hormones and Hashimoto’s thyroiditis (HT) affect carotid plaque formation, but their impact on ...
Yanmeizhi Wu +5 more
doaj +2 more sources
Sex-specific associations between obstructive sleep apnea and thyroid hormone sensitivity in euthyroid adults [PDF]
Biology of Sex DifferencesBackground The relationship between obstructive sleep apnea (OSA) and thyroid hormone sensitivity remains unclear. Thyroid hormone sensitivity indices may reveal subclinical hypothalamic-pituitary-thyroid (HPT) axis dysregulation beyond conventional ...
Beini Zhou +5 more
doaj +2 more sources
Thyroid Hormone Transporters [PDF]
Biochemical Society Transactions, 2005 Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus
Friesema, Edith +3 more
+8 more sources
Main Factors Involved in Thyroid Hormone Action
Molecules, 2021 The thyroid hormone receptors are the mediators of a multitude of actions by the thyroid hormones in cells. Most thyroid hormone activities require interaction with nuclear receptors to bind DNA and regulate the expression of target genes. In addition to
Lorena Tedeschi +3 more
doaj +1 more source
Graves’ disease coexisted with resistance to thyroid hormone: a case report
Journal of Medical Case Reports, 2021 Background Resistance to thyroid hormone is a rare autosomal dominant disorder characterized by reduced responsiveness to thyroid hormone and can cause syndrome of inappropriate secretion of thyroid stimulating hormone.
Hiroshi Akahori, Rika Usuda
doaj +1 more source
European Thyroid Journal, 2023 Objective: Central sensitivity of thyroid hormone refers to the sensitivity of hypothalamic– pituitary–thyroid (HPT) axis to the change in circulating free thyroxine (fT4).
Ying Sun +6 more
doaj +1 more source
Therapeutic Advances in Endocrinology and Metabolism, 2021 Purpose: To investigate the effect of subclinical hypothyroidism on pregnancy outcomes of women early in their pregnancy with different thyroid-stimulating hormone levels and thyroid peroxidase antibody–negative status and to explore reasonable thyroid ...
Ping Zhu +5 more
doaj +1 more source