Results 131 to 140 of about 335,864 (307)

The predictive value of thyroid hormone sensitivity parameters for cervical lymph node metastasis in patients with differentiated thyroid cancer

Annals of Medicine
Objective To comprehensively investigate the predictive value of thyroid hormone sensitivity parameters for cervical lymph node metastasis in patients diagnosed with differentiated thyroid cancer (DTC) undergoing total thyroidectomy and neck lymph node ...
Jingcheng Bi, Tianqi Yao, Yu Yao, Zhengcai Zhu, Qiucheng Lei, Lianghe Jiao, Tao Li   +6 more
doaj   +1 more source

Fish and amphibians as test organisms for evaluation of effects caused by chemicals [PDF]

, 2007
A large number of chemicals can contaminate aquatic environments and therefore be exposed to fish and amphibians during their sensitive stages of development.
Carlsson, Gunnar
core  

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

A review of complex hormone regulation in thyroid cancer: novel insights beyond the hypothalamus–pituitary–thyroid axis

Frontiers in Endocrinology
Like the ovaries and prostate, the thyroid exhibits characteristic hormone secretion and regulation. Thyroid cancer (TC), especially differentiated thyroid carcinoma, has typical sex-specific and age-specific hormone-driven clinical features.
Liu-han Chen, Tao Xie, Qian Lei, Yan-rui Gu, Chuan-zheng Sun   +4 more
doaj   +1 more source

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Prevalence of endogenous normal thyroid function 3 years after hemithyroidectomy for differentiated thyroid cancer

European Thyroid Journal
Objective: To investigate the prevalence of endogenous normal thyroid function 3 years after hemithyroidectomy for low-risk differentiated thyroid cancer if a postoperative thyroid-stimulating hormone increase up to 4 mIU/L is accepted.
Tina Toft Kristensen, Christina Caroline Plaschke, Anne Fog Lomholt, Christoffer Holst Hahn, Irene Wessel, Mads Aage Toft Kristensen, Jens Bentzen, Christina Ellervik   +7 more
doaj   +1 more source

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition and Cancer Risk: Insights from a Large Propensity‐Matched Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon, Chen Gurevitz, Tzippy Shochat, Shiri Kushnir, Guy Witberg, Amos Levi, Dan Gilon, Ran Kornowski, Paaladinesh Thavendiranathan, Husam Abdel Qadir, Zaza Iakobishvili   +10 more
wiley   +1 more source

Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri, Islam R. Younis, Shadia I. Jalal, Theodore F. Logan, Rohan Maniar, Steven M. Bray, Sara K. Quinney, Zeruesenay Desta, Todd C. Skaar, James E. Tisdale, Tyler Shugg   +10 more
wiley   +1 more source

Correlation of Fine Needle Aspiration Cytology and Histopathology in Thyroid Nodules: A Six‐Year Study at a Tertiary Public Laboratory in the Western Cape Province, South Africa

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Fine‐needle aspiration cytology (FNAC) is the primary screening test for thyroid nodules. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) provides six diagnostic categories, each with an implied risk of malignancy (ROM). This study evaluated the performance of thyroid FNAC and the application of TBSRTC categories in
Raymond Chimatira, Brendon Price
wiley   +1 more source

Diagnostic Utility of Ki‐67 Index on Cell Block Material for Grading Medullary Thyroid Carcinoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction An international grading system for medullary thyroid carcinoma (IMTCGS) was established in 2022. High‐grade MTC is defined by the presence of one or more of the following features: mitotic index ≥ 5 per 2 mm2, Ki‐67 proliferative index ≥ 5%, or tumor necrosis.
Tieying Hou, Hector Mesa, Bianca Puello, Brent Molden   +3 more
wiley   +1 more source