Results 151 to 160 of about 583,270 (252)

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Thyroid Hormone Resistance in children

, 2003
Thyroid Hormone Resistance (RTH) is characterized by the diminished response of thyroid hormone-responsive tissues in varying degrees in association with elevated serum levels of total and free T4 and T3 and inappropriately normal or elevated TSH levels.
ERCAN, Oya, Laron, Z., Krassas, G., Ercal, D., Berberoglu, M.   +4 more
core  

Embodied attachments: IVF, the maternal body, and the making of embryo kinship

Feminist Anthropology, EarlyView.
Abstract Within the sphere of IVF (in vitro fertilization), there is increasing concern about the stockpiles of frozen embryos held in clinics across the country. This normative discourse tends to take the patient‐embryo relationship for granted, with salient political consequences for current embryo ‘personhood’ debates.
Manon Lefevre
wiley   +1 more source

LXRα and PPARα Mediated Hepatic Lipid Metabolic Disruption Induced by the UV Filter EHMC in 2D and 3D HepaRG Cell Models

Food Safety and Health, EarlyView.
Dietary UV filter EHMC induces hepatic steatosis in HepaRG cells at noncytotoxic concentrations. Mechanistically, EHMC binds nuclear receptors (LXRα, PPARα), upregulating SREBP‐1 to accelerate fatty acid synthesis. These findings highlight the potential metabolic toxicity of widespread EHMC exposure through food sources.
Shanglin Yang, Na Li, Yingnan Han, Mei Ma   +3 more
wiley   +1 more source

Potential of Seaweed to Improve the Quality and Shelf Life of Fish and Fishery Products

Food Safety and Health, EarlyView.
Growing global demand for safe fish preservation has increased interest in natural alternatives. Seaweed‐derived bioactive compounds possess antioxidant and antimicrobial properties that enhance fish quality, safety, and shelf life. These sustainable preservatives may reduce spoilage and synthetic preservative use, though further research ...
Ashika Banu Rodela, Md. Golam Rasul, Ilias Ebne Kabir, Jahid Hasan, Chunhong Yuan, Bhaskar Chandra Majumdar   +5 more
wiley   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

Head &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent, Adrien Nguyen Quoc, Christine Lefevre, Laura González‐Briceño, Caroline Thalassinos, Isabelle Flechtner, Dulanjalee Kariyawasam, Yamina Dassa, Magali Viaud, Dinane Samara‐Boustani, Graziella Pinto, Hervé Monpeyssen, Sabine Sarnacki, Vincent Couloigner, Michel Polak, Athanasia Stoupa   +15 more
wiley   +1 more source

Strain and Shear Wave Elastography in Thyroid Nodules: Tissue Stiffness as a Complementary Risk Marker for Differentiating Benign, Indeterminate, and Malignant Cytology

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the diagnostic performance of shear wave elastography (SWE) and strain elastography (SE) as complementary techniques to conventional B‐mode ultrasound for differentiating benign, indeterminate, and malignant thyroid nodules. Methods This prospective cross‐sectional study included 208 thyroid nodules evaluated using B‐mode
Kairo Alexandre Alves Silveira, Icleia Siqueira Barreto, Ilka Mara Borges Botelho, Elizabeth João Pavin, Ademar Yamanaka, Denise Engelbrecht Zantut‐Wittmann   +5 more
wiley   +1 more source

Development and Preliminary Validation of a Modified Thyroid Symptom Questionnaire (TSQ)

Head &Neck, EarlyView.
ABSTRACT Background This study aimed to modify and validate the Thyroidectomy Voice and Symptom Questionnaire (TVSQ) to serve as a symptom screening tool in benign thyroid disease. Methods A 32‐item modified TVSQ was developed and administered alongside a symptom checklist to outpatients; controls were recruited to determine discriminative validity ...
Vikash Yogaraj, Debra Phyland, Catherine Sinclair   +2 more
wiley   +1 more source

Surgery After Thermal Ablation of Thyroid Nodules: A Systematic Review of Surgical Risk, Strategy and Pathological Findings

Head &Neck, EarlyView.
ABSTRACT Background Thermal ablation is increasingly used for selected thyroid nodules, but some patients subsequently require thyroidectomy. The effect of prior ablation on surgical risk, operative strategy, and histopathology remains unclear. Methods PubMed/MEDLINE, EMBASE, and the Cochrane Library were searched from inception to May 2026 for studies
Francesco Brucchi, Federica Poli, Beatrice Sperotto, Carla Colombo, Laura Fugazzola, Gianlorenzo Dionigi   +5 more
wiley   +1 more source